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Radiation Therapy With or Without SU5416 in Treating Patients With Soft Tissue Sarcoma
NCT00023725 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as SU5416 may stop the growth of cancer by stopping blood flow to the tumor. It is not yet known if radiation therapy is more effective with or without SU5416 in treating soft tissue sarcoma. PURPOSE: Phase I/II trial to compare the effectiveness of radiation therapy with or without SU5416 in treating patients who have stage IB or stage IIA soft tissue sarcoma.
Conditions Studied
Interventions
- PROCEDURE conventional surgery
- RADIATION radiation therapy
- DRUG semaxanib
Study Locations (20)
California
- Mount Diablo Medical Center — Concord
- Cancer Center and Beckman Research Institute, City of Hope — Duarte
- California Cancer Center — Fresno
- Saint Agnes Cancer Center — Fresno
- Sutter Health West Cancer Research Group — Greenbrae
- Loma Linda University Medical Center — Loma Linda
- Veterans Affairs Medical Center - Long Beach — Long Beach
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles
- Jonsson Comprehensive Cancer Center, UCLA — Los Angeles
- CCOP - Bay Area Tumor Institute — Oakland
- Huntington Cancer Center — Pasadena
- Cancer Care Center — Pomona
- Radiation Oncology Center - Sacramento — Sacramento
Alabama
- University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham
- Huntsville Hospital System — Huntsville
- Comprehensive Cancer Institute of Huntsville — Huntsville
- MBCCOP - Gulf Coast — Mobile
- Alabama Oncology, LLC — Montgomery
- Radiation Oncology Associates of West Alabama — Tuscallosa
Arizona
- Foundation for Cancer Research and Education — Phoenix
Trial Details
| Field | Value |
|---|---|
| Start Date | 2001-08 |
| Est. Completion | 2003-10 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00023725
The ClinicalTrials.gov registry entry for NCT00023725 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is Radiation Therapy Oncology Group, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Sarcoma appearing as the primary indexed condition, and to 3 interventions — of which conventional surgery is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00023725 reports 20 study locations spanning 3 distinct geographic areas — top geographies include California, Alabama, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00023725 about?
NCT00023725 is a clinical study titled "Radiation Therapy With or Without SU5416 in Treating Patients With Soft Tissue Sarcoma". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as SU5416 may stop the growth of cancer by stopping blood flow to the tumor. It is not yet known if radiation therapy is more effective with or without SU5416 in treating soft tissue sarcoma. PURPOSE: Phase I/II ...
What is the current status of trial NCT00023725?
This trial is currently completed. It is a Phase 1 study. The study started on 2001-08. Estimated completion is 2003-10.
What conditions does trial NCT00023725 study?
This clinical trial studies the following conditions: Sarcoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00023725?
The interventions under investigation include: conventional surgery (PROCEDURE), radiation therapy (RADIATION), semaxanib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00023725?
This trial is sponsored by Radiation Therapy Oncology Group, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00023725 being conducted?
This trial has 20 study locations across Alabama, Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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