Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Evaluate the Safety and Pharmacokinetics/Pharmacodynamics of HS-20118
NCT06846710 · View on ClinicalTrials.gov ↗
Study Summary
The study will be conducted in 2 parts (SAD for Part 1 and MAD for Part2). Part 1 is a single-center, randomized, double-blind, placebo-controlled, SAD study to evaluate the safety, tolerability, immunogenicity, and PK of HS-20118 after a single oral dose in healthy participants. Part 2 is a multi-center, randomized, double-blind, placebo-controlled, MAD study to evaluate the safety, tolerability, immunogenicity, PK, and PD of HS-20118 after multiple oral doses in patients with moderate to severe plaque psoriasis .
Conditions Studied
Interventions
- DRUG HS-20118
- OTHER HS-20118 placebo
Study Locations (9)
Florida
- Clinitiative - Floridian Clinical Research, LLC — Miami Lakes
- NuLine Clinical Trial Center (Network) — Pompano Beach
California
- Kinetic Clinical Research — Anaheim
Auckland
- Pacific Clinical Research Network (PCRN), Auckland — Takapuna
Christchurch
- Pacific Clinical Research Network (PCRN), Christchurch — Christchurch
Dunedin
- Momentum Clinical Research, Dunedin — Dunedin
Pukekohe
- Momentum Clinical Research, Pukekohe — Pukekohe
Upper Hutt
- Pacific Clinical Research Network (PCRN), Wellington — Upper Hutt
Wellington Region
- Momentum Clinical Research, Wellington — Mount Cook
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 132 participants |
| Start Date | 2025-05-02 |
| Est. Completion | 2027-02-28 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06846710
The ClinicalTrials.gov registry entry for NCT06846710 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 132 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jiangsu Hansoh Pharmaceutical Co., which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Psoriasis appearing as the primary indexed condition, and to 2 interventions — of which HS-20118 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06846710 reports 9 study locations spanning 8 distinct geographic areas — top geographies include Florida, California, Auckland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06846710 about?
NCT06846710 is a clinical study titled "Evaluate the Safety and Pharmacokinetics/Pharmacodynamics of HS-20118". The study will be conducted in 2 parts (SAD for Part 1 and MAD for Part2). Part 1 is a single-center, randomized, double-blind, placebo-controlled, SAD study to evaluate the safety, tolerability, immunogenicity, and PK of HS-20118 after a single oral dose in healthy participants. Part 2 is a multi-...
What is the current status of trial NCT06846710?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 132 participants. The study started on 2025-05-02. Estimated completion is 2027-02-28.
What conditions does trial NCT06846710 study?
This clinical trial studies the following conditions: Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06846710?
The interventions under investigation include: HS-20118 (DRUG), HS-20118 placebo (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06846710?
This trial is sponsored by Jiangsu Hansoh Pharmaceutical Co., which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06846710 being conducted?
This trial has 9 study locations across California, Florida, Auckland, Christchurch, Dunedin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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