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NCT04864886 · ClinicalTrials.gov registry record
Metabolic Profiling of Immune Responses in Immune-mediated Diseases
A clinical trial of Atopic Dermatitis and Psoriasis, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Recruiting
- Registry status
- 300
- Enrollment target
- 1
- Study location
NCT04864886: Recruiting study of Atopic Dermatitis and Psoriasis, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT04864886 is a study of Atopic Dermatitis and Psoriasis that is actively recruiting participants, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 300 participants, below the 607-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04864886, a study of Atopic Dermatitis and Psoriasis, is actively recruiting participants, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: The immune system is the part of the body that fights infection. Some people have immune deficiencies that cause skin rashes, make them get sick often with infections, or make it difficult for their skin to heal. Researchers want to learn more to better treat conditions that affect immune response. Objective: To learn about how the immune system and skin healing are related to each other. Eligibility: People ages 18-75 with primary immune deficiency, eczema, or psoriasis. Healthy volunteers are also needed. Design: Participants will be screened with a medical and medicine history and a physical exam. They may take a pregnancy test. Participants will discuss the medicines or supplements they take as well as skin products they use, such as soaps and lotions. Participants will have up to 4 skin biopsies taken from the forearm. A needle will inject an anesthetic into the skin where the biopsy will be done. A sharp tool that looks like a tiny cookie cutter will be used to remove a round plug of skin a bit smaller than the tip of a pencil. Participants will give at least 1 blood sample. Participants may have optional skin swab collection. A cotton swab will be used to swab the skin on the arm. Participants may have optional skin tape collection. A sticky strip of tape will be placed on the arm and then removed. Participants may give leftover samples taken as part of their regular medical care. Participation will last for about 4 days. Participants will have 2 visits that each last about 1 hour. They may be asked to repeat the study in the future. ...
Primary Outcome
Determine whether there are abnormalities in specific tissue repair pathways, such as epithelial to mesenchymal transition (EMT) are associated with immune-mediated disorders.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2021-08-10 |
| Est. Completion | 2027-06-30 |
What NCT04864886 shows while recruiting
NCT04864886 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 607-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (51% lower).
The record links to 4 conditions, with Atopic Dermatitis appearing as the primary indexed condition, and to 0 interventions.
NCT04864886 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04864886 about?
NCT04864886 is a clinical study titled "Metabolic Profiling of Immune Responses in Immune-mediated Diseases". Background: The immune system is the part of the body that fights infection. Some people have immune deficiencies that cause skin rashes, make them get sick often with infections, or make it difficult for their skin to heal. Researchers want to learn more to better treat conditions that affect immu...
What is the current status of trial NCT04864886?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2021-08-10. Estimated completion is 2027-06-30.
What conditions does trial NCT04864886 study?
This clinical trial studies the following conditions: Atopic Dermatitis, Psoriasis, Primary Immunodeficiency, Immune-mediated Diseases.
Who is sponsoring clinical trial NCT04864886?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04864886 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04864886's enrollment target sits among peer trials
300 42nd of 150 higher than 108 of 150 other Atopic Dermatitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Atopic Dermatitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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