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ClinicalTrials.gov 26 recruiting now full pipeline #93 of 28,707 conditions

Psoriasis: full-pipeline trial registry

26 of 127 indexed Psoriasis trials are currently recruiting.

Corpus placement: #93 of 28,707 conditions by registered trial count.

127 US clinical trials · 26 currently recruiting · #93 of 28,707 conditions by registered trial count

Psoriasis: 127 US clinical trials tracked, 26 recruiting.

Psoriasis is the subject of 127 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 50 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Bristol-Myers Squibb, running 8 of these trials.

Enrollment posture brief

Registry condition psoriasis

OPEN 26 | RECR 20% | LATE 50 | EARLY 36 | RANK #93 | SPON 8

Nearest open-share peer: Healthy (21% recruiting · 1,096 trials)

Head and Neck Squamous Cell 56.8%Sarcoma45%Solid Tumors33.9%Smoking21.8%Psoriasis (this)20%
Open-enrollment share among volume-matched conditions near Psoriasis

Psoriasis lists 26 open slots (20% of 127 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Psoriasis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Psoriasis is recruiting below its size-band peers.

    26 of 127 indexed trials (20.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Psoriasis trials is spread across many organizations.

    Bristol-Myers Squibb accounts for 8 of 127 trials (6.3%). 65 distinct sponsors appear on at least one study for this condition label.

  3. Typical Psoriasis enrolment sits around 84 participants.

    Median target enrolment is 84 among the 126 trials that report a genuine target (sentinel values excluded). 68 of those (54%) plan for fewer than 100 participants.

  4. Psoriasis research is mostly interventional.

    101 interventional and 26 observational studies make up this index (79.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 120Phase 216Phase 326Phase 424

Open and recent trials

127 total, page 2 of 3

COMPLETED Phase 3 480 participants

Long Term Study to Evaluate Safety and Efficacy of M518101 in Subjects With Plaque Psoriasis

Maruho North America

NCT01908595

COMPLETED Phase 2 426 participants

A Study to Assess the Efficacy and Safety of PPC-06 (Tepilamide Fumarate)

Dr. Reddy's Laboratories Limited

NCT03421197

COMPLETED 409 participants

Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index

Northwestern University

NCT00879944

COMPLETED Phase 3 394 participants

A Comparison of DFD01 Spray Versus Comp01 Lotion, Vehicle Spray and Vehicle Lotion in Subjects With Moderate Psoriasis

Primus Pharmaceuticals

NCT01947491

COMPLETED Phase 4 352 participants

Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy

AbbVie

NCT04908475

COMPLETED Phase 3 327 participants

Risankizumab Versus Secukinumab for Participants With Moderate to Severe Plaque Psoriasis

AbbVie

NCT03478787

COMPLETED Phase 3 303 participants

A Study of the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Moderate to Severe Plaque Psoriasis of the Scalp

Amgen

NCT03123471

COMPLETED NA 300 participants

Collaborative Connected Health (CCH) for PCORI

University of Southern California

NCT02358135

COMPLETED Phase 2 271 participants

A Phase 2b Study of Baricitinib in Participants With Moderate to Severe Psoriasis

Eli Lilly and Company

NCT01490632

COMPLETED Phase 2 268 participants

Study to Evaluate Effectiveness and Safety in Subjects With Moderate to Severe Psoriasis

Bristol-Myers Squibb

NCT02931838

COMPLETED Phase 3 250 participants

Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis

Amgen

NCT01690299

COMPLETED Phase 3 234 participants

An Efficacy and Safety Study of Two Dose Levels of Certolizumab Pegol (CZP) in Subjects With Plaque Psoriasis (PSO)

UCB Biopharma S.P.R.L.

NCT02326298

COMPLETED 232 participants

Measuring the Treatment Preferences of Participants in Japan With Moderate-to-Severe Psoriasis (PsO) Using Discrete Choice Experiment

Bristol-Myers Squibb

NCT05065762

COMPLETED Phase 3 227 participants

A Study to Evaluate the Efficacy and Safety of Two Dose Levels of Certolizumab Pegol (CZP) in Subjects With Plaque Psoriasis (PSO)

UCB Biopharma S.P.R.L.

NCT02326272

COMPLETED Phase 2 199 participants

A Dose Ranging Study of the Effect of Ruxolitinib Phosphate Cream When Applied to Participants With Plaque Psoriasis

Incyte Corporation

NCT00778700

COMPLETED Phase 4 180 participants

A Study to Evaluate the Effect of Deucravacitinib on Quality of Life in Participants With Plaque Psoriasis in a Community Setting

Bristol-Myers Squibb

NCT05701995

COMPLETED Phase 2 166 participants

BI 655066 Dose Ranging in Psoriasis, Active Comparator Ustekinumab

Boehringer Ingelheim

NCT02054481

COMPLETED Phase 3 160 participants

A Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis

Amgen

NCT04175613

COMPLETED Phase 3 152 participants

Open Label Study of Adalimumab in Subjects Who Have a Sub-optimal Response to Systemic Therapy or Phototherapy

Abbott

NCT00566722

COMPLETED Phase 2 152 participants

Study to Evaluate the Efficacy and Safety of JTE-451 in Subjects With Moderate to Severe Plaque Psoriasis

Akros Pharma

NCT03832738

COMPLETED Phase 2 142 participants

A Study in Participants With Moderate to Severe Psoriasis

Eli Lilly and Company

NCT01107457

COMPLETED Phase 3 139 participants

A Study of Subcutaneous Risankizumab Injection for Pediatric Participants With Moderate to Severe Plaque Psoriasis to Assess Change in Disease Symptoms

AbbVie

NCT04435600

COMPLETED Phase 2 124 participants

A Study to Explore Efficacy and Safety of ASP015K in Subjects With Moderate to Severe Psoriasis

Astellas Pharma

NCT01096862

COMPLETED Phase 3 120 participants

Effects of Desoximetasone Spray 0.25% in Patients With Moderate to Severe Plaque Psoriasis

Sun Pharmaceutical Industries

NCT01206660

COMPLETED Phase 3 108 participants

A Study to Assess Usability of Risankizumab Autoinjector Combination Product in Participants With Moderate to Severe Plaque Psoriasis

AbbVie

NCT03875508

COMPLETED 103 participants

Serum, Cellular and Imaging Markers of Arthritis in Psoriasis Patients

University of Rochester

NCT02413801

COMPLETED Phase 2 99 participants

Randomized Study of PH-10 for Psoriasis

Provectus Pharmaceuticals

NCT01247818

COMPLETED Phase 1 94 participants

Topically Applied IDP-118 Lotion and HP Monad Lotion in Subjects With Moderate to Severe Plaque Psoriasis

Bausch Health Americas

NCT03058744

COMPLETED 86 participants

Genetic Analysis of Pediatric Psoriasis

Northwestern University

NCT03768284

COMPLETED NA 84 participants

Mind Matters: A High Touch, Low Cost Approach to Improving Mental Health Outcomes in Patients With Psoriatic Diseases

Elaine Husni

NCT05571696

COMPLETED Phase 3 78 participants

Efficacy and Safety Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis

Janssen Research & Development

NCT02905331

COMPLETED Phase 1 76 participants

Study Evaluating The Safety And Tolerability Of ILV-094 In Subjects With Psoriasis

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00563524

COMPLETED Phase 2 66 participants

A Study of R3421 in Patients With Moderate to Severe Chronic Plaque Psoriasis.

Hoffmann-La Roche

NCT00504270

COMPLETED Phase 2 64 participants

Evaluation of Clinical Outcomes in an Online Teledermatology Model for the Management of Psoriasis

University of California, Davis

NCT00971477

COMPLETED 64 participants

Prevalence of Sleep Disturbances in Psoriasis

Wake Forest University Health Sciences

NCT00895375

COMPLETED Phase 4 63 participants

Olux E Foam and Sorilux Foam Combination Therapy for the Maintenance of Treatment Response in Patients With Moderate Plaque Psoriasis

Leon Kircik, M.D.

NCT01745133

COMPLETED 62 participants

Characterization of Lipoprotein Composition and Function in Pediatric Psoriasis Before and After Treatment

Northwestern University

NCT03791216

COMPLETED Phase 4 60 participants

Study of the Efficacy of Cloderm® Cream in the Treatment of Moderate Plaque Psoriasis

Promius Pharma

NCT01714544

COMPLETED 59 participants

Sleep, Circadian Rhythm & Skin Health

University Hospitals Cleveland Medical Center

NCT02457000

COMPLETED Phase 1 59 participants

Multiple Dose Escalation Study In Medically Stable Subjects With Psoriasis

Pfizer

NCT01736696

COMPLETED Phase 1 54 participants

An Investigational Study of Cyclosporine on Experimental Medication BMS-986165 in Healthy Male Participants

Bristol-Myers Squibb

NCT03419910

COMPLETED Phase 1 54 participants

A Safety, Tolerability and Pharmacokinetics Study of Topical Ointment YR001 in Adult Healthy Volunteers

Hangzhou Yirui Pharmaceutical Technology Co.

NCT05718921

COMPLETED Phase 1 49 participants

A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation

Bristol-Myers Squibb

NCT03254784

COMPLETED Phase 4 43 participants

Vascular Inflammation in Psoriasis-Ustekinumab (VIP-U)

University of Pennsylvania

NCT02187172

COMPLETED Phase 2 42 participants

A Study of Safety, Tolerability and Pharmacokinetics of Apremilast (CC-10004) in Pediatric Subjects With Moderate to Severe Plaque Psoriasis

Amgen

NCT02576678

COMPLETED Phase 2 40 participants

Study of the Clinical Activity, Safety, and Tolerability of SRT2104 in Subjects With Moderate to Severe Plaque-Type Psoriasis

Sirtris, a GSK Company

NCT01154101

COMPLETED Phase 1 40 participants

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of AbGn-168 in Psoriasis

Boehringer Ingelheim

NCT00848055

COMPLETED Phase 1 40 participants

Single Ascending Dose Study of PRX003 in Healthy Subjects

Prothena Biosciences Limited

NCT02458677

COMPLETED Phase 4 36 participants

MIcrovascular dysfuNction In Moderate-severe Psoriasis

Marcelo F. Di Carli, MD, FACC

NCT04271540

COMPLETED Phase 4 36 participants

The Quality of Life Study in Psoriasis Patients After Ustekinumab Treatment

University of California, San Francisco

NCT01511315

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Phase Distribution

PhaseTrial count
Phase 1 20
Phase 2 16
Phase 3 26
Phase 4 24

Named interventions

Most-linked intervention names on Psoriasis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
13 trials
Ustekinumab Drug
7 trials
Apremilast Drug
6 trials
Placebo Other
6 trials
Guselkumab Drug
5 trials
Risankizumab Drug
4 trials
M518101 Drug
3 trials
Vehicle Drug
3 trials

US sites by state

Facility locations filed on Psoriasis trials. A trial with sites in several states counts in each.

California 63 trials
Florida 40 trials
New York 31 trials
Illinois 26 trials
Texas 25 trials
Indiana 25 trials
Georgia 22 trials
North Carolina 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Psoriasis page

127 registered trials, 26 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Psoriasis condition card totals 127 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.