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ClinicalTrials.gov 275 recruiting now early-phase tilt #4 of 28,963 conditions

Prostate Cancer: early-phase trial registry

275 of 749 indexed Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4 of 28,963 conditions by registered trial count.

749 US clinical trials · 275 currently recruiting · #4 of 28,963 conditions by registered trial count

Prostate Cancer: 749 US clinical trials tracked, 275 recruiting.

Prostate Cancer is the subject of 749 registered US clinical trials on ClinicalTrials.gov, 275 of them currently open to new participants. 75 are in Phase 3-4 (later-stage) and 344 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 53 of these trials.

Open enrollment, early-phase tilt

Prostate Cancer has 749 registered US clinical trials, 275 of them open to new participants right now, about 37% of the total.

275
recruiting participants now
37%
of trials open to enrollment
75
in Phase 3-4 (later-stage)
53
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #4 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Prostate Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostate Cancer recruits in line with its size-band peers.

    275 of 749 indexed trials (36.7%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostate Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 53 of 749 trials (7.1%). 283 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostate Cancer enrolment sits around 82 participants.

    Median target enrolment is 82 among the 736 trials that report a genuine target (sentinel values excluded). 389 of those (52.9%) plan for fewer than 100 participants.

  4. Prostate Cancer research is mostly interventional.

    628 interventional and 121 observational studies make up this index (83.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1156Phase 2188Phase 362Phase 413

Open and recent trials

749 total, page 4 of 15

RECRUITING NA 100 participants

Effect of Education on Treatment Decision Making for Patients With Prostate Cancer on Chronic Hormone Treatments

University of Chicago

NCT04705038

RECRUITING NA 100 participants

Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

Northwell Health

NCT05384535

RECRUITING Phase 2 100 participants

FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer

Cellvax Therapeutics

NCT06636682

RECRUITING 100 participants

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Washington University School of Medicine

NCT04354064

RECRUITING NA 100 participants

The CArdiovascular Risk Evaluation in Men With Prostate Cancer Study (CARE-PC) Pilot Feasibility Study

Vivek Narayan

NCT06064149

RECRUITING 100 participants

Prostate Assessment with Restriction Spectrum Imaging (RSI) MRI

University of California, San Diego

NCT04992728

RECRUITING 100 participants

Comprehensive Monitoring of Men With Prostate Cancer Cared for by "Active Surveillance

M.D. Anderson Cancer Center

NCT05840484

RECRUITING NA 100 participants

ASCVD Management Using CCTA in Prostate Cancer Patients on ADT

Indiana University

NCT05879913

RECRUITING NA 100 participants

The Florida ASCENT Study

University of Florida

NCT07042243

RECRUITING Early Phase 1 100 participants

Pragmatic Trial of Metformin for Glucose Intolerance or Increased BMI in Prostate Cancer Patients

University of Colorado, Denver

NCT05515978

RECRUITING Phase 2 100 participants

AMNIOX CORD Study - Radical Prostatectomy With and Without Cryopreserved Umbilical Cord Allograft

Hackensack Meridian Health

NCT04263025

RECRUITING Phase 1 100 participants

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Apollo Therapeutics

NCT06399757

RECRUITING Phase 2 99 participants

A Study of 2141-V11 in Combination With Standard Treatments in People With Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT06347705

RECRUITING NA 91 participants

Evaluation of Tumor Control Based on Serial Multiparametric MRI and Post-Treatment Biopsies For Patients Treated With Dose Intensification to the Dominant Intra-Prostatic Lesion (DIL) Using Ultra-Hypofractionated, MR-Guided Radiotherapy

NYU Langone Health

NCT06542757

RECRUITING Phase 1 91 participants

64Cu-GRIP B in Patients With Advanced Malignancies

Rahul Aggarwal

NCT05888532

RECRUITING NA 90 participants

Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT06138067

RECRUITING Phase 1 90 participants

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

Clasp Therapeutics

NCT06778863

RECRUITING Phase 2 90 participants

A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer

University of Chicago

NCT05726292

RECRUITING NA 90 participants

Understanding of Genetics by Men at Risk for Prostate Cancer

Mayo Clinic

NCT04550845

RECRUITING Phase 2 88 participants

High-Risk Metachronous Oligometastatic Prostate Cancer Trial

University of Maryland, Baltimore

NCT06212583

RECRUITING NA 86 participants

Jump: MR Simulation For Radiation Therapy Master Protocol

Brigham and Women's Hospital

NCT04545957

RECRUITING NA 85 participants

Culturally Adapting an Intervention to Increase Genetic Testing in African American Cancer Survivors

Barbara Ann Karmanos Cancer Institute

NCT07436078

RECRUITING NA 84 participants

Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial

Palette Life Sciences

NCT06496256

RECRUITING Phase 1 82 participants

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

Blue Earth Therapeutics

NCT05413850

RECRUITING Early Phase 1 80 participants

Pilot Study of (MR) Imaging with Pyruvate (13C) to Detect High Grade Prostate Cancer

Ivan de Kouchkovsky, MD

NCT02526368

RECRUITING Phase 1 80 participants

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Angiex

NCT06440005

RECRUITING 80 participants

SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT06389097

RECRUITING NA 80 participants

Tumor Genomic Pre-test Counseling Tool for Black or African-American Men With Prostate Cancer

University of California, San Francisco

NCT06171139

RECRUITING Phase 1 80 participants

Two Fraction Prostate SBRT With DIL SIB

NYU Langone Health

NCT05864196

RECRUITING NA 80 participants

Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial

Dana-Farber Cancer Institute

NCT06040125

RECRUITING NA 78 participants

Feasibility of Timesaving When Using Histolog Confocal Laser Endomicroscopy for Margin Assessment in Prostatectomy Specimen

Icahn School of Medicine at Mount Sinai

NCT07141121

RECRUITING Phase 2 75 participants

Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer

Ivan de Kouchkovsky, MD

NCT04346225

RECRUITING NA 75 participants

Stratagen Quantitative Prostate MRI Platform Pilot Study

Stratagen Bio

NCT06985238

RECRUITING NA 74 participants

Impact of Multimodal Telerehabilitation in Rural Patients With Metastatic Prostate Cancer

University of Utah

NCT07032584

RECRUITING NA 70 participants

Utility of 18F-rhPSMA-7.3 in the Diagnosis of Prostate Cancer After Focal Gland Treatment

Hackensack Meridian Health

NCT07011342

RECRUITING NA 70 participants

Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

Proton Collaborative Group

NCT00969111

RECRUITING Phase 2 70 participants

4-aminopyridine Treatment for Nerve Injury

John Elfar

NCT03701581

RECRUITING Phase 2 68 participants

Phase II Trial of PSA Response-based Androgen Deprivation Therapy and Nodal Coverage for Prostate Cancer Early Salvage Radiotherapy (RANGER)

University of Texas Southwestern Medical Center

NCT07313241

RECRUITING Phase 2 68 participants

Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy

David Oh

NCT03821246

RECRUITING Phase 2 66 participants

A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer

Debiopharm International

NCT06395753

RECRUITING Phase 2 65 participants

Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

National Cancer Institute (NCI)

NCT06096870

RECRUITING Phase 2 64 participants

Pembro With Radiation With or Without Olaparib

Zin W Myint

NCT05568550

RECRUITING NA 62 participants

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy

Dana-Farber Cancer Institute

NCT05327465

RECRUITING Phase 2 60 participants

Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc

VA Office of Research and Development

NCT06084338

RECRUITING Phase 2 60 participants

Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance

University of California, San Francisco

NCT03933670

RECRUITING Phase 2 60 participants

Castrate Resistant Prostate Cancer Enhertu Therapy

Washington D.C. Veterans Affairs Medical Center

NCT06610825

RECRUITING NA 60 participants

Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life

University of Chicago

NCT06171269

RECRUITING Phase 2 60 participants

GU-01: Glycyrrhizin in Prostate Cancer

University of Illinois at Chicago

NCT06378346

RECRUITING Phase 2 60 participants

PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores

H. Lee Moffitt Cancer Center and Research Institute

NCT03495427

RECRUITING Phase 1 60 participants

Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer

University of Wisconsin, Madison

NCT04989946

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Phase Distribution

PhaseTrial count
Phase 1 156
Phase 2 188
Phase 3 62
Phase 4 13

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Prostate Cancer right now

275 recruiting of 749 indexed (37% open).

Phase mix: 75 late (III/IV) vs 344 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (53 trials), 9 others listed. 50 shown below, recruiting first. #4 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Prostate Cancer?

PlainTrial tracks 749 US clinical trials for Prostate Cancer, of which 275 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prostate Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.