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NCT06389097 · ClinicalTrials.gov registry record

SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization

A clinical trial of Prostate Cancer and Advanced Cancer, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Recruiting
Registry status
80
Enrollment target
1
Study location

NCT06389097 is a study of Prostate Cancer and Advanced Cancer that is actively recruiting participants, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 80 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06389097, a study of Prostate Cancer and Advanced Cancer, is actively recruiting participants, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

RECRUITING
Registry status
80 participants
Enrollment target
1
Study location

Study Summary

The investigators will study SPECT imaging of radiopharmaceutical therapies given as standard of care or as part of other compatible research protocols. The goal is to validate the quantitative SPECT image reconstruction methods developed in this proposal, and to investigate the relation between dosimetry calculated from SPECT images and the outcomes. Patients will be recruited for SPECT/CT imaging during treatment. This is an observational study no additional new drugs or activities will be administrated. The investigators will perform SPECT imaging on a total of 80 patients (\~20 each from year 2 to year 5). Each participant will be imaged 3 times after the first and last cycles of planned radiopharmaceutical therapy.

Interventions

  • RADIATION Radium-223
  • RADIATION 177Lu-DOTATATE
  • RADIATION 177Lu-PSMA-617

Study Locations (1)

Maryland

  • Johns Hopkins University - Baltimore

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2025-02-03
Est. Completion 2029-08

What the Registry Record Tells You About NCT06389097

The ClinicalTrials.gov registry entry for NCT06389097 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (87% lower). The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Prostate Cancer appearing as the primary indexed condition, and to 3 interventions - of which Radium-223 is the first listed.

NCT06389097 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT06389097 about?

NCT06389097 is a clinical study titled "SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization". The investigators will study SPECT imaging of radiopharmaceutical therapies given as standard of care or as part of other compatible research protocols. The goal is to validate the quantitative SPECT image reconstruction methods developed in this proposal, and to investigate the relation between dos...

What is the current status of trial NCT06389097?

This trial is currently recruiting. The enrollment target is 80 participants. The study started on 2025-02-03. Estimated completion is 2029-08.

What conditions does trial NCT06389097 study?

This clinical trial studies the following conditions: Prostate Cancer, Advanced Cancer.

What interventions are being tested in trial NCT06389097?

The interventions under investigation include: Radium-223 (RADIATION), 177Lu-DOTATATE (RADIATION), 177Lu-PSMA-617 (RADIATION).

Who is sponsoring clinical trial NCT06389097?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06389097 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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