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NCT04346225 · ClinicalTrials.gov registry record · Phase 2
Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer
A Phase 2 study of Prostate Cancer and Advanced Prostate Carcinoma, sponsored by Ivan de Kouchkovsky, MD.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT04346225: Recruiting Phase 2 study of Prostate Cancer and Advanced Prostate Carcinoma, sponsored by Ivan de Kouchkovsky, MD.
NCT04346225 is a Phase 2 study of Prostate Cancer and Advanced Prostate Carcinoma that is actively recruiting participants, run by Ivan de Kouchkovsky, MD. The registered enrollment target is 75 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04346225, a Phase 2 study of Prostate Cancer and Advanced Prostate Carcinoma, is actively recruiting participants, sponsored by Ivan de Kouchkovsky, MD.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective imaging study evaluating the utility of baseline metabolic MR imaging as a diagnostic and response monitoring tool in patients with advanced prostate cancer. Preliminary pre-clinical and clinical data demonstrates the ability of HP C-13 pyruvate/metabolic MR imaging to detect high-grade prostate cancer, including cancer with neuroendocrine differentiation, as well as provide early evidence of metabolic response and resistance following application of systemic therapies for the treatment of advanced prostate cancer patients. In the proposed study, the investigators aim is to extend the initial clinical results and further develop HP C-13 MRI as an imaging modality in advanced prostate cancer.
Conditions Studied
Interventions
- PROCEDURE Magnetic Resonance Imaging (MRI)
- DRUG Hyperpolarized C13
Study Locations (1)
California
- University of California, San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2020-07-16 |
| Est. Completion | 2026-11-30 |
| Phase | Phase 2 |
What NCT04346225 shows while recruiting
NCT04346225 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (88% lower).
The record links to 2 conditions, with Prostate Cancer appearing as the primary indexed condition, and to 2 interventions - of which Magnetic Resonance Imaging (MRI) is the first listed.
NCT04346225 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04346225 about?
NCT04346225 is a clinical study titled "Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer". This is a prospective imaging study evaluating the utility of baseline metabolic MR imaging as a diagnostic and response monitoring tool in patients with advanced prostate cancer. Preliminary pre-clinical and clinical data demonstrates the ability of HP C-13 pyruvate/metabolic MR imaging to detect h...
What is the current status of trial NCT04346225?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 75 participants. The study started on 2020-07-16. Estimated completion is 2026-11-30.
What conditions does trial NCT04346225 study?
This clinical trial studies the following conditions: Prostate Cancer, Advanced Prostate Carcinoma.
What interventions are being tested in trial NCT04346225?
The interventions under investigation include: Magnetic Resonance Imaging (MRI) (PROCEDURE), Hyperpolarized C13 (DRUG).
Who is sponsoring clinical trial NCT04346225?
This trial is sponsored by Ivan de Kouchkovsky, MD, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04346225 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04346225's enrollment target sits among peer trials
75 392nd of 735 higher than 341 of 735 other Prostate Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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