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ClinicalTrials.gov 3 recruiting now early-phase tilt

Primary Peritoneal Cavity Cancer: early-phase trial registry

3 of 23 indexed Primary Peritoneal Cavity Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #724 of 28,707 conditions by registered trial count.

23 US clinical trials · 3 currently recruiting · #724 of 28,707 conditions by registered trial count

Primary Peritoneal Cavity Cancer: 23 US clinical trials tracked, 3 recruiting.

Primary Peritoneal Cavity Cancer is the subject of 23 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 8 of these trials.

Enrollment posture brief

Registry condition primary-peritoneal-cavity-cancer

OPEN 3 | RECR 13% | LATE 1 | EARLY 21 | RANK #724 | SPON 8

Nearest open-share peer: Chest Pain (13% recruiting · 23 trials)

Breast Cancer Stage II47.8%Advanced Non-Small-Cell Lung39.1%Anxiety Disorder30.4%Barrett's Esophagus26.1%Primary Peritoneal Cavit (th…13%
Open-enrollment share among volume-matched conditions near Primary Peritoneal Cavity Cancer

Primary Peritoneal Cavity Cancer lists 3 open slots (13% of 23 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Primary Peritoneal Cavity Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Primary Peritoneal Cavity Cancer is recruiting below its size-band peers.

    3 of 23 indexed trials (13%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Primary Peritoneal Cavity Cancer research.

    National Cancer Institute (NCI) accounts for 8 of 23 trials (34.8%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Primary Peritoneal Cavity Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 35 among the 16 trials that report a genuine target (sentinel values excluded). 12 of those (75%) plan for fewer than 100 participants.

  4. Primary Peritoneal Cavity Cancer research is mostly interventional.

    23 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 211Phase 31

Open and recent trials

23 total, page 1 of 1

RECRUITING Phase 1 319 participants

A Study of XMT-1660 in Participants With Solid Tumors

Mersana Therapeutics

NCT05377996

RECRUITING Phase 1 33 participants

Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

Masonic Cancer Center, University of Minnesota

NCT06342986

RECRUITING Phase 2 18 participants

Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT06617923

COMPLETED NA 375 participants

Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer

Wake Forest University Health Sciences

NCT01656044

COMPLETED Phase 3 324 participants

Paclitaxel and Cisplatin in Treating Patients With Stage III or Stage IV Ovarian Cancer or Primary Peritoneal Cancer

Gynecologic Oncology Group

NCT00002717

COMPLETED Phase 2 136 participants

Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix

Wake Forest University Health Sciences

NCT01580410

COMPLETED Phase 2 61 participants

Irofulven in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cancer

National Cancer Institute (NCI)

NCT00053365

COMPLETED Phase 2 60 participants

Temsirolimus in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

National Cancer Institute (NCI)

NCT00429793

COMPLETED Phase 2 48 participants

3-AP and Cisplatin in Treating Patients With Recurrent or Persistent Platinum-Resistant Ovarian Epithelial or Primary Peritoneal Cancer

National Cancer Institute (NCI)

NCT00081276

COMPLETED Phase 2 35 participants

Bevacizumab and Erlotinib in Treating Patients With Recurrent or Metastatic Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

National Cancer Institute (NCI)

NCT00126542

COMPLETED Phase 1 30 participants

Radiolabeled Monoclonal Antibody, Paclitaxel, and Interferon Alfa in Treating Patients With Recurrent Ovarian Cancer

National Cancer Institute (NCI)

NCT00002734

COMPLETED Phase 2 30 participants

Interleukin-12 in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer

National Cancer Institute (NCI)

NCT00016289

COMPLETED Phase 2 29 participants

Gemcitabine Hydrochloride and Tanespimycin in Treating Patients With Recurrent Advanced Ovarian Epithelial or Peritoneal Cavity Cancer

National Cancer Institute (NCI)

NCT00093496

COMPLETED Phase 2 29 participants

Belinostat and Carboplatin in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Carboplatin or Cisplatin

National Cancer Institute (NCI)

NCT00993616

COMPLETED Phase 1 24 participants

Topotecan Plus Etoposide in Treating Patients With Recurrent Ovarian, Peritoneal, or Fallopian Tube Cancer

Gynecologic Oncology Group

NCT00003967

COMPLETED Phase 1 3 participants

FT516 and IL2 With Enoblituzumab for Ovarian Cancer

Masonic Cancer Center, University of Minnesota

NCT04630769

COMPLETED Phase 1

Vaccine Therapy in Treating Patients With Ovarian, Fallopian Tube, or Peritoneal Cancer

Memorial Sloan Kettering Cancer Center

NCT00006041

COMPLETED Phase 1

Monoclonal Antibody Vaccine Therapy in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer

Memorial Sloan Kettering Cancer Center

NCT00058435

COMPLETED Phase 2

Hormone Therapy With Arzoxifene Hydrochloride in Treating Women With Metastatic Refractory Ovarian Cancer or Primary Peritoneal Cancer

Eli Lilly and Company

NCT00003670

COMPLETED Phase 1

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial or Primary Peritoneal Cancer

Gynecologic Oncology Group

NCT00005026

COMPLETED Phase 1

Combination Chemotherapy in Treating Patients With Previously Untreated, Newly Diagnosed Epithelial Tumors

Beth Israel Deaconess Medical Center

NCT00004082

COMPLETED Phase 1

CT-2103 in Treating Patients With Recurrent Ovarian Epithelial or Fallopian Tube Cancer or Primary Peritoneal Cancer

Memorial Sloan Kettering Cancer Center

NCT00017017

COMPLETED Phase 2

Laparoscopic Staging in Patients With Ovarian, Fallopian Tube, or Other Primary Abdominal Cancers

Gynecologic Oncology Group

NCT00002538

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 11
Phase 3 1

Named interventions

Most-linked intervention names on Primary Peritoneal Cavity Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

topotecan hydrochloride Drug
3 trials
paclitaxel Drug
3 trials
carboplatin Drug
3 trials
gemcitabine hydrochloride Drug
2 trials
cisplatin Drug
2 trials
laboratory biomarker analysis Other
2 trials
IP FT516 Drug
1 trials
hyperthermic intraperitoneal chemotherapy Drug
1 trials

US sites by state

Facility locations filed on Primary Peritoneal Cavity Cancer trials. A trial with sites in several states counts in each.

Pennsylvania 7 trials
Illinois 6 trials
Minnesota 5 trials
Maryland 5 trials
New York 4 trials
North Carolina 4 trials
Massachusetts 4 trials
California 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Primary Peritoneal Cavity Cancer page

23 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Primary Peritoneal Cavity Cancer condition card totals 23 registered trials; most-linked intervention topotecan hydrochloride; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.