Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Chest Pain: early-phase trial registry
3 of 23 indexed Chest Pain trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #724 of 28,707 conditions by registered trial count.
23 US clinical trials · 3 currently recruiting · #724 of 28,707 conditions by registered trial count
Chest Pain: 23 US clinical trials tracked, 3 recruiting.
Chest Pain is the subject of 23 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Wake Forest University Health Sciences, running 4 of these trials.
Enrollment posture brief
Registry condition chest-pain
OPEN 3 | RECR 13% | LATE 0 | EARLY 2 | RANK #724 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Primary Peritoneal Cavity Cancer (13% recruiting · 23 trials)
Chest Pain lists 3 open slots (13% of 23 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Chest Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Chest Pain is recruiting below its size-band peers.
3 of 23 indexed trials (13%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Chest Pain research.
Wake Forest University Health Sciences accounts for 4 of 23 trials (17.4%). 19 distinct sponsors appear on at least one study for this condition label.
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Typical Chest Pain enrolment sits around 360 participants.
Median target enrolment is 360 among the 23 trials that report a genuine target (sentinel values excluded). 7 of those (30.4%) plan for fewer than 100 participants.
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Chest Pain splits between interventional and observational designs.
14 interventional and 9 observational studies make up this index (60.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
23 total, page 1 of 1
Evaluation of Patients With Non-obstructive Coronary Arteries
Stanford University
NCT00823563
CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)
Wake Forest University Health Sciences
NCT05897632
Virtual Reality for Non-cardiac Chest Pain
Mayo Clinic
NCT06262126
Patient-centered Treatment of Anxiety After Low-Risk Chest Pain in the Emergency Room
Indiana University
NCT04811521
Intraoperative Echocardiography in Low-Risk CABG Surgery
University of Pennsylvania
NCT06154265
HEART Pathway Implementation
Wake Forest University Health Sciences
NCT02056964
ECG Methods for the Prompt Identification of Coronary Events
University of Pittsburgh
NCT04237688
Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree
CardioDx
NCT00500617
Coronary Computed Tomography for Systematic Triage of Acute Chest Pain Patients to Treatment (CT-STAT)
Corewell Health East
NCT00468325
Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES)
CardioDx
NCT01117506
PARA-HEART Pilot Implementation
Wake Forest University Health Sciences
NCT02709135
Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain
Montefiore Medical Center
NCT01384448
Emergency Department Cardiac Ultrasound
Hennepin Healthcare Research Institute
NCT02719509
MRI Evaluation of Chest Pain
National Heart, Lung, and Blood Institute (NHLBI)
NCT00001961
Evaluation of Synthesized 18-Lead ECG in the Emergency Department
Nihon Kohden
NCT03426436
At-Home Automated External Defibrillator (AED) Training Study
Public Health - Seattle and King County
NCT00219674
Understanding Pediatric Chest Pain and Other Symptoms
Emory University
NCT00166231
Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain
Wake Forest University Health Sciences
NCT00678639
Chest Pain Perception and Capsaicin Sensitivity
Bassett Healthcare
NCT02346903
Non-Interruptive Alerts for Improving Use of Clinical Decision Rules
University of Utah
NCT04702308
Comparing Sports Bra Design in Full Busted Women
University of Houston
NCT05456594
A Study of the Feasibility of Prehospital Remote Ischemic Conditioning
University of North Carolina, Chapel Hill
NCT03400579
Cardiac SPECT With Rotating Slant Hole Collimator
Johns Hopkins University
NCT00328315
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Chest Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Chest Pain trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Chest Pain page
23 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Chest Pain trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Wake Forest University Health Sciences sponsors the most Chest Pain trials on record, review their full trial history before evaluating a specific study. See Wake Forest University Health Sciences's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chest Pain condition card totals 23 registered trials; most-linked intervention Corus CAD (ASGES); top US site state North Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.