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2026 data Public-data reference. official source

Chest Pain

Open-data reference.

23 US clinical trials · 3 currently recruiting

Active & Recent Trials

RECRUITING 2,000 participants

Evaluation of Patients With Non-obstructive Coronary Arteries

Stanford University

NCT00823563

RECRUITING NA 502 participants

CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)

Wake Forest University Health Sciences

NCT05897632

RECRUITING NA 10 participants

Virtual Reality for Non-cardiac Chest Pain

Mayo Clinic

NCT06262126

ACTIVE NOT RECRUITING NA 375 participants

Patient-centered Treatment of Anxiety After Low-Risk Chest Pain in the Emergency Room

Indiana University

NCT04811521

ACTIVE NOT RECRUITING NA 40 participants

Intraoperative Echocardiography in Low-Risk CABG Surgery

University of Pennsylvania

NCT06154265

COMPLETED 14,717 participants

HEART Pathway Implementation

Wake Forest University Health Sciences

NCT02056964

COMPLETED 6,000 participants

ECG Methods for the Prompt Identification of Coronary Events

University of Pittsburgh

NCT04237688

COMPLETED 4,350 participants

Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree

CardioDx

NCT00500617

COMPLETED NA 750 participants

Coronary Computed Tomography for Systematic Triage of Acute Chest Pain Patients to Treatment (CT-STAT)

Corewell Health East

NCT00468325

COMPLETED 581 participants

Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES)

CardioDx

NCT01117506

COMPLETED 511 participants

PARA-HEART Pilot Implementation

Wake Forest University Health Sciences

NCT02709135

COMPLETED NA 400 participants

Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain

Montefiore Medical Center

NCT01384448

COMPLETED 380 participants

Emergency Department Cardiac Ultrasound

Hennepin Healthcare Research Institute

NCT02719509

COMPLETED Phase 2 360 participants

MRI Evaluation of Chest Pain

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001961

COMPLETED NA 314 participants

Evaluation of Synthesized 18-Lead ECG in the Emergency Department

Nihon Kohden

NCT03426436

COMPLETED Phase 2 305 participants

At-Home Automated External Defibrillator (AED) Training Study

Public Health - Seattle and King County

NCT00219674

COMPLETED 156 participants

Understanding Pediatric Chest Pain and Other Symptoms

Emory University

NCT00166231

COMPLETED NA 110 participants

Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain

Wake Forest University Health Sciences

NCT00678639

COMPLETED NA 99 participants

Chest Pain Perception and Capsaicin Sensitivity

Bassett Healthcare

NCT02346903

COMPLETED NA 70 participants

Non-Interruptive Alerts for Improving Use of Clinical Decision Rules

University of Utah

NCT04702308

COMPLETED NA 33 participants

Comparing Sports Bra Design in Full Busted Women

University of Houston

NCT05456594

COMPLETED NA 10 participants

A Study of the Feasibility of Prehospital Remote Ischemic Conditioning

University of North Carolina, Chapel Hill

NCT03400579

COMPLETED 5 participants

Cardiac SPECT With Rotating Slant Hole Collimator

Johns Hopkins University

NCT00328315

Phase Distribution

PhaseTrial count
Phase 2 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chest Pain Trial Landscape

ClinicalTrials.gov lists 23 US studies indexed under Chest Pain, and 3 of those are currently open to recruitment — roughly 13% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Chest Pain shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Chest Pain is led by Wake Forest University Health Sciences with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 23 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chest Pain?

PlainTrial tracks 23 US clinical trials for Chest Pain, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chest Pain?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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