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ClinicalTrials.gov 77 recruiting now official registry

Pregnancy clinical trials

77 of 194 indexed Pregnancy trials are currently recruiting.

194 US clinical trials · 77 currently recruiting

Pregnancy is the subject of 194 registered US clinical trials on ClinicalTrials.gov, 77 of them currently open to new participants. 11 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), running 8 of these trials.

The research picture

Pregnancy has 194 registered US clinical trials, 77 of them open to new participants right now, about 40% of the total.

77
recruiting participants now
40%
of trials open to enrollment
11
in Phase 3–4 (later-stage)
8
top sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Phase 18Phase 24Phase 39Phase 42

Active & Recent Trials

194 total, page 3 of 4

COMPLETED 4,673 participants

Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00342667

COMPLETED 2,546 participants

Labor Induction With Oral Versus Vaginal Misoprostol

University of Texas Southwestern Medical Center

NCT04755218

COMPLETED 2,502 participants

Noninvasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker

Sequenom

NCT00971334

COMPLETED Phase 1 2,210 participants

Parents Matter!: Interventions to Promote Effective Parent-Child Communication

Centers for Disease Control and Prevention

NCT00137943

COMPLETED 1,919 participants

Fetal Growth Evaluation by Three-Dimensional Ultrasound

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00340171

COMPLETED Phase 3 1,600 participants

A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00000751

COMPLETED 1,506 participants

Happy Mommy! Happy Baby! Study

University of Pennsylvania

NCT01700374

COMPLETED Phase 3 1,496 participants

The Safety and Effectiveness of Zidovudine in HIV-Infected Pregnant Women and Their Infants

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000960

COMPLETED 1,470 participants

Feasibility of Medical Abortion by Direct-to-Consumer Telemedicine

Gynuity Health Projects

NCT02513043

COMPLETED NA 1,450 participants

Louisville Teen Pregnancy Prevention Project

University of Louisville

NCT01411878

COMPLETED Phase 4 1,233 participants

Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women

Yale University

NCT00628771

COMPLETED 1,090 participants

Development of Standards for the New Ballard Maturation Score

NICHD Neonatal Research Network

NCT01203449

COMPLETED NA 1,072 participants

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

Johns Hopkins Bloomberg School of Public Health

NCT02904629

COMPLETED 918 participants

Clinical Evaluation of the ARIES Group B Streptococcus (GBS) Assay

Luminex Corporation

NCT02497430

COMPLETED 850 participants

The Effect of Fetal Gender on Maternal Substance Abuse Treatment

Johns Hopkins University

NCT00882648

COMPLETED NA 746 participants

Increasing Use of Publicly Reported Pediatric Quality Data

Baystate Medical Center

NCT01784575

COMPLETED 648 participants

Cervical Volume by Three-Dimensional Ultrasound as a Predictor of Preterm Delivery

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00342550

COMPLETED NA 600 participants

Study of Having a Female Friend as Labor Support

Saint Peters University Hospital

NCT00127361

COMPLETED NA 598 participants

Evaluation of the Effectiveness of the Teen Options to Prevent Pregnancy (T.O.P.P.) Program

Mathematica Policy Research

NCT01456793

COMPLETED NA 574 participants

Internet-Based Sexual Health Education for Middle School Native American Youth

The University of Texas Health Science Center, Houston

NCT01303575

COMPLETED 565 participants

Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD)

Stanford University

NCT01730170

COMPLETED 505 participants

Vulnerability of the Fetus/Infant to PAH, PM2.5 AND ETS.

National Institute of Environmental Health Sciences (NIEHS)

NCT00044603

COMPLETED 500 participants

PLAC1 in Reproduction

University of South Florida

NCT01277848

COMPLETED 458 participants

Pregnancy Eating Attributes Study

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT02217462

COMPLETED NA 415 participants

Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT

Medical University of South Carolina

NCT04630249

COMPLETED 413 participants

Feasibility of Telemedicine Medical Abortion

Gynuity Health Projects

NCT04599725

COMPLETED NA 400 participants

Osteopathic Manipulative Medicine in Pregnancy: Physiologic and Clinical Effects

University of North Texas Health Science Center

NCT00426244

COMPLETED 376 participants

Pregnancy Exposure Registry for Tysabri®

Biogen

NCT00472992

COMPLETED Phase 1 351 participants

Safety and Effectiveness of Taking Choline Supplements During Pregnancy for Improving Infant Brain Development

University of Colorado, Denver

NCT00332124

COMPLETED NA 325 participants

Skin-to Skin Contact on Newborn Temperature

Rachel Baker

NCT02143193

COMPLETED 320 participants

Fetal Programming of Obesity

Arkansas Children's Hospital Research Institute

NCT01131117

COMPLETED NA 301 participants

Self-Retaining Retractor in Obese Patients Undergoing Cesarean Section

St. Louis University

NCT01826604

COMPLETED Phase 3 300 participants

Induction With Misoprostol: Oral Mucosa Versus Vaginal Epithelium (IMPROVE)

Indiana University

NCT02408315

COMPLETED Phase 3 292 participants

TIPPS: Thrombophilia in Pregnancy Prophylaxis Study

Ottawa Hospital Research Institute

NCT00967382

COMPLETED 287 participants

Immune Responses to the Flu Shot During Pregnancy

Lisa Christian

NCT02148874

COMPLETED NA 282 participants

Evaluating the Effects of Supplemental Vitamin C on Infant Lung Function in Pregnant Smoking Women

Oregon Health and Science University

NCT00632476

COMPLETED NA 281 participants

Maternal-Offspring Metabolics:Family Intervention Trial

Northwestern University

NCT01631747

COMPLETED 239 participants

The MOMENTUM Study (Monitoring Maternal Emergency Navigation and Triage on Mfangano

University of Minnesota

NCT03942536

COMPLETED NA 204 participants

Use of Peanut Labor Ball Following Epidural Anesthesia

TriHealth

NCT02190591

COMPLETED 204 participants

Clearblue Pregnancy Test - Lay User Study

SPD Development Company Limited

NCT04043169

COMPLETED NA 154 participants

Mobius® Post-cesarean Pain Randomized Control Trial

Abbey Hardy-Fairbanks

NCT00685932

COMPLETED NA 150 participants

A Comparison of Manual vs. Spontaneous Removal of the Placenta at Cesarean Section

University of Rochester

NCT00375986

COMPLETED 144 participants

The Cymbalta Pregnancy Registry

Eli Lilly and Company

NCT01074151

COMPLETED NA 142 participants

Healthy Motivations for Moms-to-be Study

University of South Carolina

NCT03063528

COMPLETED NA 136 participants

Incentives Targeting Gestational Weight Gain in Overweight/Obese Low Income Women

University of Vermont

NCT02233673

COMPLETED NA 130 participants

Oral Contraceptive Pills Compared to Vaginal Rings

University of California, San Francisco

NCT00357526

COMPLETED 130 participants

Identify Clinical Conditions That Increase Circulating DNA Levels

University of Florida

NCT01815996

COMPLETED NA 130 participants

Phone-Based Postpartum Continuing Care for Smoking Cessation

Battelle Memorial Institute

NCT01684592

COMPLETED NA 129 participants

Holistic Assessment of Tulsa Children's Health

University of Oklahoma

NCT04158089

COMPLETED 129 participants

A Study of HIV Levels During Pregnancy and After Childbirth

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00041964

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Reading the Pregnancy Trial Landscape

194 indexed Pregnancy studies · 77 recruiting (40%).

Phase mix: 11 late (III/IV) vs 12 early (I/II).

Top sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (8 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pregnancy?

PlainTrial tracks 194 US clinical trials for Pregnancy, of which 77 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pregnancy?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.