Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04755218 · ClinicalTrials.gov registry record
Labor Induction With Oral Versus Vaginal Misoprostol
A clinical trial of Pregnancy and Labor, Induced, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- 2,546
- Enrollment target
- 1
- Study location
NCT04755218: Completed study of Pregnancy and Labor, Induced, sponsored by University of Texas Southwestern Medical Center.
NCT04755218 is a study of Pregnancy and Labor, Induced that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 2,546 participants, above the 859-participant average among 191 other Pregnancy trials with a reported enrollment target (196% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04755218, a study of Pregnancy and Labor, Induced, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- 2,546 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will compare vaginal and oral misoprostol, to determine whether a vaginal misoprostol regimen achieves a higher vaginal delivery rate in a real-world, high-volume setting, and whether this regimen reduces time and oxytocin need on a high-volume Labor and Delivery unit at Parkland Hospital. Our primary hypothesis is that among women with singleton, term pregnancies, cervical dilation 2cm or less, and indicated labor induction, the rate of vaginal delivery is significantly increased when a standardized vaginal misoprostol regimen is used, compared with a standardized oral misoprostol regimen.
Primary Outcome
vaginal delivery at first induction
Conditions Studied
Study Locations (1)
Texas
- Parkland Health and Hospital Systems - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,546 participants |
| Start Date | 2021-05-24 |
| Est. Completion | 2023-07-07 |
What the finished NCT04755218 record still lists
NCT04755218 is an observational study that tracks outcomes without assigning an intervention. Its 2,546 participants enrollment target places it among the larger protocols in the corpus, above the 859-participant average among 191 other Pregnancy trials with a reported enrollment target (196% higher).
The record links to 2 conditions, with Pregnancy appearing as the primary indexed condition, and to 0 interventions.
NCT04755218 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04755218 about?
NCT04755218 is a clinical study titled "Labor Induction With Oral Versus Vaginal Misoprostol". This study will compare vaginal and oral misoprostol, to determine whether a vaginal misoprostol regimen achieves a higher vaginal delivery rate in a real-world, high-volume setting, and whether this regimen reduces time and oxytocin need on a high-volume Labor and Delivery unit at Parkland Hospital...
What is the current status of trial NCT04755218?
This trial is currently completed. The enrollment target is 2,546 participants. The study started on 2021-05-24. Estimated completion is 2023-07-07.
What conditions does trial NCT04755218 study?
This clinical trial studies the following conditions: Pregnancy, Labor, Induced.
Who is sponsoring clinical trial NCT04755218?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04755218 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pregnancy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04755218's enrollment target sits among peer trials
2,546 12th of 191 higher than 180 of 191 other Pregnancy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pregnancy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project
RECRUITING
-
CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes
RECRUITING · NA
-
Healthy Start: Exploring the Fuel-mediated Programming of Neonatal Growth
RECRUITING
-
Cocooned Moms Study
RECRUITING · NA
-
Retinal Vascular Changes During Pregnancy
RECRUITING
-
CGM for Management of Type 2 Diabetes in Pregnancy
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT05931276 · 2,540 participants · Phase 3
CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
- NCT00018057 · 2,530 participants · Phase 2
Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders
- NCT04142177 · 2,529 participants · NA
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response
- NCT06018285 · 2,572 participants · NA
Stepped Approach to Reducing Risk of Suicide in Primary Care
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI