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NCT00342667 · ClinicalTrials.gov registry record
Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes
A clinical trial of Pregnancy and Preterm Birth, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
- Completed
- Registry status
- 4,673
- Enrollment target
- 5
- Study locations
NCT00342667: Completed study of Pregnancy and Preterm Birth, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
NCT00342667 is a study of Pregnancy and Preterm Birth that has completed, run by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The registered enrollment target is 4,673 participants, above the 848-participant average among 191 other Pregnancy trials with a reported enrollment target (451% higher). The trial reports 5 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00342667, a study of Pregnancy and Preterm Birth, has completed, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
- COMPLETED
- Registry status
- 4,673 participants
- Enrollment target
- 5
- Study locations
Study Summary
A major goal of modern perinatal and neonatal medicine is to reduce the rate of developmental disabilities, especially mental retardation. Cerebral palsy is frequently associated with neurologic abnormalities and mental retardation. Improvements in neonatal intensive care have resulted in improved survival of very low birthweight infants but also in an increased frequency of cerebral palsy. Prematurity is a leading risk factor for cerebral palsy. Two thirds of preterm neonates are born to mothers with preterm labor with intact membranes or preterm premature rupture of membranes. A growing body of evidence suggests that these conditions are heterogeneous. This is an observational cohort study designed to identify the mechanisms of disease in patients with preterm labor/contractions and preterm premature rupture of membranes and to describe the relationship between clinical, biochemical, histological, biophysical parameters and the development of infant neurological disorders.
Primary Outcome
Establish the relationship between these pathologic sub- groups (i.e., intrauterine infection and non infection associated preterm labor /contractions and preterm PROM ) and short and long term neonatal outcome.
Conditions Studied
Study Locations (5)
Other
- Sotero del Rio Hospital - Puente Alto
- Ben Gurion University /Soroka Medical Center - Beersheba
- Seoul National University Hospital - Seoul
Maryland
- National Institute of Child Health and Human Development (NICHD), 9000 Rockville - Bethesda
Michigan
- Hutzel Women's Hospital - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4,673 participants |
| Start Date | 1997-12-08 |
| Est. Completion | 2014-09-15 |
Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)305 total trials
What the finished NCT00342667 record still lists
NCT00342667 is an observational study that tracks outcomes without assigning an intervention. Its 4,673 participants enrollment target places it among the larger protocols in the corpus, above the 848-participant average among 191 other Pregnancy trials with a reported enrollment target (451% higher).
The record links to 2 conditions, with Pregnancy appearing as the primary indexed condition, and to 0 interventions.
NCT00342667 lists 5 locations in 3 states (Other, Maryland, Michigan).
Frequently Asked Questions
What is clinical trial NCT00342667 about?
NCT00342667 is a clinical study titled "Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes". A major goal of modern perinatal and neonatal medicine is to reduce the rate of developmental disabilities, especially mental retardation. Cerebral palsy is frequently associated with neurologic abnormalities and mental retardation. Improvements in neonatal intensive care have resulted in improved s...
What is the current status of trial NCT00342667?
This trial is currently completed. The enrollment target is 4,673 participants. The study started on 1997-12-08. Estimated completion is 2014-09-15.
What conditions does trial NCT00342667 study?
This clinical trial studies the following conditions: Pregnancy, Preterm Birth.
Who is sponsoring clinical trial NCT00342667?
This trial is sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00342667 being conducted?
This trial has 5 study locations across Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pregnancy
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Where NCT00342667's enrollment target sits among peer trials
4,673 7th of 191 higher than 185 of 191 other Pregnancy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pregnancy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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