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NCT00342667 · ClinicalTrials.gov registry record

Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes

A clinical trial of Pregnancy and Preterm Birth, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

Completed
Registry status
4,673
Enrollment target
5
Study locations

NCT00342667 is a study of Pregnancy and Preterm Birth that has completed, run by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The registered enrollment target is 4,673 participants, above the 848-participant average among 191 other Pregnancy trials with a reported enrollment target (451% higher). The trial reports 5 study locations across 3 states.

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The verdict

NCT00342667, a study of Pregnancy and Preterm Birth, has completed, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

COMPLETED
Registry status
4,673 participants
Enrollment target
5
Study locations

Study Summary

A major goal of modern perinatal and neonatal medicine is to reduce the rate of developmental disabilities, especially mental retardation. Cerebral palsy is frequently associated with neurologic abnormalities and mental retardation. Improvements in neonatal intensive care have resulted in improved survival of very low birthweight infants but also in an increased frequency of cerebral palsy. Prematurity is a leading risk factor for cerebral palsy. Two thirds of preterm neonates are born to mothers with preterm labor with intact membranes or preterm premature rupture of membranes. A growing body of evidence suggests that these conditions are heterogeneous. This is an observational cohort study designed to identify the mechanisms of disease in patients with preterm labor/contractions and preterm premature rupture of membranes and to describe the relationship between clinical, biochemical, histological, biophysical parameters and the development of infant neurological disorders.

Conditions Studied

Study Locations (5)

Other

  • Sotero del Rio Hospital - Puente Alto
  • Ben Gurion University /Soroka Medical Center - Beersheba
  • Seoul National University Hospital - Seoul

Maryland

  • National Institute of Child Health and Human Development (NICHD), 9000 Rockville - Bethesda

Michigan

  • Hutzel Women's Hospital - Detroit

Trial Details

FieldValue
Enrollment Target 4,673 participants
Start Date 1997-12-08
Est. Completion 2014-09-15

What the Registry Record Tells You About NCT00342667

The ClinicalTrials.gov registry entry for NCT00342667 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 4,673 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 848-participant average among 191 other Pregnancy trials with a reported enrollment target (451% higher). The listed sponsor is Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Pregnancy appearing as the primary indexed condition, and to 0 interventions.

NCT00342667 reports 5 study locations spanning 3 distinct geographic areas - top geographies include Other, Maryland, Michigan.

Frequently Asked Questions

What is clinical trial NCT00342667 about?

NCT00342667 is a clinical study titled "Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes". A major goal of modern perinatal and neonatal medicine is to reduce the rate of developmental disabilities, especially mental retardation. Cerebral palsy is frequently associated with neurologic abnormalities and mental retardation. Improvements in neonatal intensive care have resulted in improved s...

What is the current status of trial NCT00342667?

This trial is currently completed. The enrollment target is 4,673 participants. The study started on 1997-12-08. Estimated completion is 2014-09-15.

What conditions does trial NCT00342667 study?

This clinical trial studies the following conditions: Pregnancy, Preterm Birth.

Who is sponsoring clinical trial NCT00342667?

This trial is sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00342667 being conducted?

This trial has 5 study locations across Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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