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NCT05929911 · ClinicalTrials.gov registry record · NA

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

A NA study of HIV and Post Traumatic Stress Disorder, sponsored by Montefiore Medical Center.

Recruiting
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT05929911: Recruiting NA study of HIV and Post Traumatic Stress Disorder, sponsored by Montefiore Medical Center.

NCT05929911 is a NA study of HIV and Post Traumatic Stress Disorder that is actively recruiting participants, run by Montefiore Medical Center. The registered enrollment target is 20 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05929911, a NA study of HIV and Post Traumatic Stress Disorder, is actively recruiting participants, sponsored by Montefiore Medical Center.

RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

People living with HIV (PLWH) have a higher rate of post-traumatic stress disorder (PTSD) diagnosis than the general population. Comorbid PTSD is also associated with negative HIV-related health outcomes. Unfortunately, little outcome research has examined the usefulness of PTSD treatments for PTSD. This pilot study adapts for PLWH a non-exposure based psychotherapy for PTSD focused on reflecting on one's emotions and relationships and understanding and working through how trauma may have disrupted them. The study team is interested in better understanding the needs of PLWH with PTSD, learning whether PLWH with PTSD find this treatment acceptable and helpful, and beginning to understand the relationship between HIV-related health factors (e.g., inflammation and stress biology) and PTSD, and how these health factors may improve during treatment.

Primary Outcome

Lower scores denote less severe PTSD symptoms; a decline of at least 30% from an individual's baseline CAPS score is defined as a treatment response on the CAPS; diagnostic remission will be defined as achieving response plus failing to meet for DSM-5 defined PTSD per the CAPS after treatment.

Interventions

  • BEHAVIORAL Trauma-focused psychodynamic psychotherapy

Study Locations (1)

New York

  • Albert Einstein College of Medicine - The Bronx

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-04-26
Est. Completion 2026-04
Phase NA
Montefiore Medical Center

345 total trials

What NCT05929911 shows while recruiting

NCT05929911 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 440-participant average among 303 other HIV trials with a reported enrollment target (95% lower).

The record links to 2 conditions, with HIV appearing as the primary indexed condition, and to 1 intervention - of which Trauma-focused psychodynamic psychotherapy is the first listed.

NCT05929911 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT05929911 about?

NCT05929911 is a clinical study titled "Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD". People living with HIV (PLWH) have a higher rate of post-traumatic stress disorder (PTSD) diagnosis than the general population. Comorbid PTSD is also associated with negative HIV-related health outcomes. Unfortunately, little outcome research has examined the usefulness of PTSD treatments for PTSD....

What is the current status of trial NCT05929911?

This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2024-04-26. Estimated completion is 2026-04.

What conditions does trial NCT05929911 study?

This clinical trial studies the following conditions: HIV, Post Traumatic Stress Disorder.

What interventions are being tested in trial NCT05929911?

The interventions under investigation include: Trauma-focused psychodynamic psychotherapy (BEHAVIORAL).

Who is sponsoring clinical trial NCT05929911?

This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05929911 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05929911's enrollment target sits among peer trials

20 284th of 303 higher than 18 of 303 other HIV trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05929911, the US trial registry maintained by the National Library of Medicine. NCT05929911 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.