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NCT05117632 · ClinicalTrials.gov registry record · Phase 2

ALTO-100 in MDD and/or PTSD

A Phase 2 study of Major Depressive Disorder and Post Traumatic Stress Disorder, sponsored by Alto Neuroscience.

Completed
Registry status
Phase 2
Development phase
245
Enrollment target
20
Study locations

NCT05117632 is a Phase 2 study of Major Depressive Disorder and Post Traumatic Stress Disorder that has completed, run by Alto Neuroscience. The registered enrollment target is 245 participants, below the 376-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (35% lower). The trial reports 20 study locations across 13 states.

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The verdict

NCT05117632, a Phase 2 study of Major Depressive Disorder and Post Traumatic Stress Disorder, has completed, sponsored by Alto Neuroscience.

COMPLETED
Registry status
Phase 2
Development phase
245 participants
Enrollment target
20
Study locations

Study Summary

The goal of this study is to collect biologically based data for defining predictors and correlates of the effects of ALTO-100.

Interventions

  • DRUG ALTO-100 PO tablet

Study Locations (20)

California

  • Site 141 - Costa Mesa
  • Site 118 - Fresno
  • Site 116 - Martinez
  • Site 116 - Mather

Texas

  • Site 147 - Fort Worth
  • Site 148 - Fort Worth
  • Site 120 - Houston
  • Site 113 - Houston

Florida

  • Site 150 - Boca Raton
  • Site 112 - Doral

Arizona

  • Site 136 - Tempe

Arkansas

  • Site 139 - Little Rock

Illinois

  • Site 155 - Elgin

Indiana

  • Site 137 - Noblesville

Maryland

  • Site 151 - Baltimore

Trial Details

FieldValue
Enrollment Target 245 participants
Start Date 2021-12-20
Est. Completion 2022-12-09
Phase Phase 2

Sponsor

Alto Neuroscience

10 total trials

What the Registry Record Tells You About NCT05117632

The ClinicalTrials.gov registry entry for NCT05117632 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 245 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 376-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (35% lower). The listed sponsor is Alto Neuroscience, which has 10 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Major Depressive Disorder appearing as the primary indexed condition, and to 1 intervention - of which ALTO-100 PO tablet is the first listed.

NCT05117632 reports 20 study locations spanning 13 distinct geographic areas - top geographies include California, Texas, Florida.

Frequently Asked Questions

What is clinical trial NCT05117632 about?

NCT05117632 is a clinical study titled "ALTO-100 in MDD and/or PTSD". The goal of this study is to collect biologically based data for defining predictors and correlates of the effects of ALTO-100.

What is the current status of trial NCT05117632?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 245 participants. The study started on 2021-12-20. Estimated completion is 2022-12-09.

What conditions does trial NCT05117632 study?

This clinical trial studies the following conditions: Major Depressive Disorder, Post Traumatic Stress Disorder.

What interventions are being tested in trial NCT05117632?

The interventions under investigation include: ALTO-100 PO tablet (DRUG).

Who is sponsoring clinical trial NCT05117632?

This trial is sponsored by Alto Neuroscience, which has 10 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05117632 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.