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ClinicalTrials.gov 306 recruiting now early-phase tilt #3 of 28,963 conditions

Obesity: early-phase trial registry

306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #3 of 28,963 conditions by registered trial count.

1,057 US clinical trials · 306 currently recruiting · #3 of 28,963 conditions by registered trial count

Obesity: 1,057 US clinical trials tracked, 306 recruiting.

Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.

Open enrollment, early-phase tilt

Obesity has 1,057 registered US clinical trials, 306 of them open to new participants right now, about 29% of the total.

306
recruiting participants now
29%
of trials open to enrollment
107
in Phase 3-4 (later-stage)
48
top sponsor: Eli Lilly and Company

Corpus placement: #3 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Obesity is recruiting below its size-band peers.

    306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Obesity trials is spread across many organizations.

    Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.

  3. Typical Obesity enrolment sits around 90 participants.

    Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.

  4. Obesity research is mostly interventional.

    894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 195Phase 2101Phase 369Phase 438

Open and recent trials

1,057 total, page 12 of 22

COMPLETED NA 373 participants

Study of an International Commercial Program on Weight Loss and Health Outcomes

University of North Carolina, Chapel Hill

NCT03571893

COMPLETED NA 364 participants

Evaluation of an Enhanced Delivery Model for Go NAPSACC

University of North Carolina, Chapel Hill

NCT03938103

COMPLETED NA 356 participants

New Moves - Obesity Prevention Among Adolescent Girls

University of Minnesota

NCT00250497

COMPLETED NA 346 participants

Using Partners to Enhance Long-Term Weight Loss

University of Wisconsin, Madison

NCT03801174

COMPLETED NA 344 participants

Weight Management Skills in African American Outpatients

University of Pennsylvania

NCT00146081

COMPLETED NA 342 participants

Food, Fun, & Fitness Internet Program for Girls: Outcome Evaluation

Baylor College of Medicine

NCT01481948

COMPLETED NA 339 participants

Heart-Healthy Lenoir Lifestyle Study

University of North Carolina, Chapel Hill

NCT01433484

COMPLETED NA 338 participants

Growing Resilience in Wind River Indian Reservation

University of Wyoming

NCT02672748

COMPLETED Phase 2 338 participants

A Study of LY3437943 in Participants Who Have Obesity or Are Overweight

Eli Lilly and Company

NCT04881760

COMPLETED Phase 2 335 participants

Effects of Co-administration of Canagliflozin 300 mg and Phentermine 15 mg With Placebo in the Treatment of Non-Diabetic Overweight and Obese Participants

Janssen Research & Development

NCT02243202

COMPLETED 314 participants

Black Family Eating Behaviors Study

National Human Genome Research Institute (NHGRI)

NCT02015078

COMPLETED NA 311 participants

Fast Food Photo Study 2

Carnegie Mellon University

NCT02452658

COMPLETED NA 309 participants

Fast Food Photo Study

Carnegie Mellon University

NCT02267954

COMPLETED Phase 4 307 participants

The Safety and Effectiveness of Low and High Carbohydrate Diets

Temple University

NCT00079547

COMPLETED 305 participants

Pediatric Behavioral Informatics to Prevent Cancer

University of Massachusetts, Boston

NCT01768533

COMPLETED NA 302 participants

Effectiveness of Patient-centered Community Health Worker Support to Help Patients Control Chronic Disease

University of Pennsylvania

NCT01900470

COMPLETED Phase 2 300 participants

Comparison of Popular Weight Loss Diets

National Center for Complementary and Integrative Health (NCCIH)

NCT00079573

COMPLETED NA 300 participants

Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients

Massachusetts General Hospital

NCT02551640

COMPLETED NA 300 participants

State-wide Health Approach to Increase Reach and Effectiveness: Study 3

The Miriam Hospital

NCT01760486

COMPLETED 300 participants

Fit Moms in Partners, Children, and Other Members

California Polytechnic State University-San Luis Obispo

NCT01921959

COMPLETED NA 300 participants

Fitness Training in Children

University of Wisconsin, Madison

NCT00205296

COMPLETED NA 300 participants

School-Based Intervention to Increase Physical Activity Among Adolescent Females

National Heart, Lung, and Blood Institute (NHLBI)

NCT00296101

COMPLETED Phase 1 292 participants

Barriers to Treatment in Obese Adolescents

Virginia Commonwealth University

NCT00167830

COMPLETED NA 292 participants

Making Calories Count: Information Format and Food Choice

University of Pennsylvania

NCT01346449

COMPLETED 290 participants

Role of Dietary Habits in Efficacy of Bariatric Surgery - Study A

Brigham and Women's Hospital

NCT03470558

COMPLETED NA 288 participants

Spatz Adjustable Balloon for Obesity (SABO)

Spatz FGIA

NCT02812160

COMPLETED NA 287 participants

A Randomized Trial of Recommendations for Exercise to Prevent Weight Regain

University of Kansas

NCT01664715

COMPLETED Phase 2 280 participants

The Effect of Betahistine on Body Weight in Obese Subjects

OBEcure

NCT00409305

COMPLETED NA 277 participants

Toddler Overweight Prevention Study Among Low-Income Families

University of Maryland, Baltimore

NCT02615158

COMPLETED NA 276 participants

Project Activate: Mindfulness and Acceptance Based Behavioral Treatment for Weight Loss

Drexel University

NCT04337619

COMPLETED NA 270 participants

Weight Watchers Online

The Miriam Hospital

NCT01888172

COMPLETED Phase 2 270 participants

Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women

National Heart, Lung, and Blood Institute (NHLBI)

NCT00666172

COMPLETED NA 270 participants

Diabetes CKD Lifestyle Technology Study

NYU Langone Health

NCT02266823

COMPLETED Phase 2 261 participants

Effects of Resistance and Aerobic Exercise on Cardiovascular Health

Duke University

NCT00275145

COMPLETED NA 261 participants

Think Health! A Personal Weight Management Program

University of Pennsylvania

NCT00959608

COMPLETED NA 259 participants

The Weigh Forward, Financial Incentives for Maintenance of Weight Loss

University of Pennsylvania

NCT02538783

COMPLETED Phase 2 258 participants

A Study to Examine the Safety, Tolerability, and Body Weight Effect of Pramlintide Alone and in Combination With Oral Antiobesity Agents in Overweight and Obese Subjects

AstraZeneca

NCT00402077

COMPLETED NA 254 participants

Veterans Walk for Health Study

US Department of Veterans Affairs

NCT00123435

COMPLETED NA 248 participants

Dissemination of the Look Ahead Weight Management Treatment in the Military

University of Tennessee

NCT02063178

COMPLETED NA 244 participants

Fruits and Vegetables Incentives Study

University of Pennsylvania

NCT04235413

COMPLETED NA 244 participants

Healthy Kids & Families: Overcoming Social, Environmental and Family Barriers to Childhood Obesity Prevention

University of Massachusetts, Worcester

NCT03028233

COMPLETED Phase 3 242 participants

Method-of-Use Study Assessing the Effect of Naltrexone Sustained Release (SR)/ Bupropion SR on Body Weight and Cardiovascular Risk Factors in Overweight and Obese Subjects

Orexigen Therapeutics

NCT01764386

COMPLETED NA 238 participants

Weight Loss Maintenance in Primary Care

Drexel University

NCT00455780

COMPLETED NA 234 participants

Framingham State Food Study

Boston Children's Hospital

NCT02068885

COMPLETED NA 234 participants

Peer Navigators to Address Obesity-Related Concerns for African Americans With Serious Mental Illness

Illinois Institute of Technology

NCT03382782

COMPLETED NA 233 participants

Ethnic Dance and Screen Time Reduction to Prevent Weight Gain in Latina Girls

Stanford University

NCT00476775

COMPLETED Phase 2 231 participants

Prevention of Overfeeding During Infancy

University of California, Davis

NCT01043978

COMPLETED NA 227 participants

UCSD Take Charge Study

University of California, San Diego

NCT01345500

COMPLETED NA 225 participants

Assessing the Effectiveness of a Weight Watchers-based Lifestyle Intervention for the Primary Prevention of Type 2 Diabetes

Indiana University

NCT02000024

COMPLETED 225 participants

A Study of the Function of Hormones Present In Taste Buds

National Institute on Aging (NIA)

NCT00233298

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Phase Distribution

PhaseTrial count
Phase 1 95
Phase 2 101
Phase 3 69
Phase 4 38

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Obesity right now

306 recruiting of 1,057 indexed (29% open).

Phase mix: 107 late (III/IV) vs 196 early (I/II) (early-phase heavy).

Top sponsor: Eli Lilly and Company (48 trials), 9 others listed. 50 shown below, recruiting first. #3 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Obesity?

PlainTrial tracks 1,057 US clinical trials for Obesity, of which 306 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Obesity?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.