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Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,707 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,707 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Enrollment posture brief
Registry condition obesity
OPEN 306 | RECR 29% | LATE 107 | EARLY 196 | RANK #3 | SPON 48
Volume-matched condition peers
Nearest open-share peer: Metastatic Pancreatic Adenocarcinoma (29% recruiting · 38 trials)
Obesity lists 306 open slots (29% of 1,057 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
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Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
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Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 12 of 22
Study of an International Commercial Program on Weight Loss and Health Outcomes
University of North Carolina, Chapel Hill
NCT03571893
Evaluation of an Enhanced Delivery Model for Go NAPSACC
University of North Carolina, Chapel Hill
NCT03938103
New Moves - Obesity Prevention Among Adolescent Girls
University of Minnesota
NCT00250497
Using Partners to Enhance Long-Term Weight Loss
University of Wisconsin, Madison
NCT03801174
Weight Management Skills in African American Outpatients
University of Pennsylvania
NCT00146081
Food, Fun, & Fitness Internet Program for Girls: Outcome Evaluation
Baylor College of Medicine
NCT01481948
Heart-Healthy Lenoir Lifestyle Study
University of North Carolina, Chapel Hill
NCT01433484
Growing Resilience in Wind River Indian Reservation
University of Wyoming
NCT02672748
A Study of LY3437943 in Participants Who Have Obesity or Are Overweight
Eli Lilly and Company
NCT04881760
Effects of Co-administration of Canagliflozin 300 mg and Phentermine 15 mg With Placebo in the Treatment of Non-Diabetic Overweight and Obese Participants
Janssen Research & Development
NCT02243202
Black Family Eating Behaviors Study
National Human Genome Research Institute (NHGRI)
NCT02015078
Fast Food Photo Study 2
Carnegie Mellon University
NCT02452658
Fast Food Photo Study
Carnegie Mellon University
NCT02267954
The Safety and Effectiveness of Low and High Carbohydrate Diets
Temple University
NCT00079547
Pediatric Behavioral Informatics to Prevent Cancer
University of Massachusetts, Boston
NCT01768533
Effectiveness of Patient-centered Community Health Worker Support to Help Patients Control Chronic Disease
University of Pennsylvania
NCT01900470
Comparison of Popular Weight Loss Diets
National Center for Complementary and Integrative Health (NCCIH)
NCT00079573
Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients
Massachusetts General Hospital
NCT02551640
State-wide Health Approach to Increase Reach and Effectiveness: Study 3
The Miriam Hospital
NCT01760486
Fit Moms in Partners, Children, and Other Members
California Polytechnic State University-San Luis Obispo
NCT01921959
Fitness Training in Children
University of Wisconsin, Madison
NCT00205296
School-Based Intervention to Increase Physical Activity Among Adolescent Females
National Heart, Lung, and Blood Institute (NHLBI)
NCT00296101
Barriers to Treatment in Obese Adolescents
Virginia Commonwealth University
NCT00167830
Making Calories Count: Information Format and Food Choice
University of Pennsylvania
NCT01346449
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study A
Brigham and Women's Hospital
NCT03470558
Spatz Adjustable Balloon for Obesity (SABO)
Spatz FGIA
NCT02812160
A Randomized Trial of Recommendations for Exercise to Prevent Weight Regain
University of Kansas
NCT01664715
The Effect of Betahistine on Body Weight in Obese Subjects
OBEcure
NCT00409305
Toddler Overweight Prevention Study Among Low-Income Families
University of Maryland, Baltimore
NCT02615158
Project Activate: Mindfulness and Acceptance Based Behavioral Treatment for Weight Loss
Drexel University
NCT04337619
Weight Watchers Online
The Miriam Hospital
NCT01888172
Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women
National Heart, Lung, and Blood Institute (NHLBI)
NCT00666172
Diabetes CKD Lifestyle Technology Study
NYU Langone Health
NCT02266823
Effects of Resistance and Aerobic Exercise on Cardiovascular Health
Duke University
NCT00275145
Think Health! A Personal Weight Management Program
University of Pennsylvania
NCT00959608
The Weigh Forward, Financial Incentives for Maintenance of Weight Loss
University of Pennsylvania
NCT02538783
A Study to Examine the Safety, Tolerability, and Body Weight Effect of Pramlintide Alone and in Combination With Oral Antiobesity Agents in Overweight and Obese Subjects
AstraZeneca
NCT00402077
Veterans Walk for Health Study
US Department of Veterans Affairs
NCT00123435
Dissemination of the Look Ahead Weight Management Treatment in the Military
University of Tennessee
NCT02063178
Fruits and Vegetables Incentives Study
University of Pennsylvania
NCT04235413
Healthy Kids & Families: Overcoming Social, Environmental and Family Barriers to Childhood Obesity Prevention
University of Massachusetts, Worcester
NCT03028233
Method-of-Use Study Assessing the Effect of Naltrexone Sustained Release (SR)/ Bupropion SR on Body Weight and Cardiovascular Risk Factors in Overweight and Obese Subjects
Orexigen Therapeutics
NCT01764386
Weight Loss Maintenance in Primary Care
Drexel University
NCT00455780
Framingham State Food Study
Boston Children's Hospital
NCT02068885
Peer Navigators to Address Obesity-Related Concerns for African Americans With Serious Mental Illness
Illinois Institute of Technology
NCT03382782
Ethnic Dance and Screen Time Reduction to Prevent Weight Gain in Latina Girls
Stanford University
NCT00476775
Prevention of Overfeeding During Infancy
University of California, Davis
NCT01043978
UCSD Take Charge Study
University of California, San Diego
NCT01345500
Assessing the Effectiveness of a Weight Watchers-based Lifestyle Intervention for the Primary Prevention of Type 2 Diabetes
Indiana University
NCT02000024
A Study of the Function of Hormones Present In Taste Buds
National Institute on Aging (NIA)
NCT00233298
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Named interventions
Most-linked intervention names on Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obesity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obesity page
1,057 registered trials, 306 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 306 Obesity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Obesity trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity condition card totals 1,057 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.