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ClinicalTrials.gov 10 recruiting now early-phase tilt

Myeloma: early-phase trial registry

10 of 30 indexed Myeloma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #519 of 28,707 conditions by registered trial count.

30 US clinical trials · 10 currently recruiting · #519 of 28,707 conditions by registered trial count

Myeloma: 30 US clinical trials tracked, 10 recruiting.

Myeloma is the subject of 30 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 23 in Phase 1-2 (earlier-stage). The most active sponsor is David Rizzieri, MD, running 3 of these trials.

Enrollment posture brief

Registry condition myeloma

OPEN 10 | RECR 33% | LATE 0 | EARLY 23 | RANK #519 | SPON 3

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

AML60%Acute Myeloid Leukemia40%Myeloma (this)33%Anatomic Stage IA Breast Can26.7%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Myeloma

Myeloma lists 10 open slots (33% of 30 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Myeloma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Myeloma is recruiting below its size-band peers.

    10 of 30 indexed trials (33.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Myeloma trials is spread across many organizations.

    David Rizzieri, MD accounts for 3 of 30 trials (10%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Most Myeloma trials plan to enrol fewer than 100 people.

    Median target enrolment is 49 among the 30 trials that report a genuine target (sentinel values excluded). 24 of those (80%) plan for fewer than 100 participants.

  4. Myeloma research is mostly interventional.

    29 interventional and 1 observational studies make up this index (96.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 115Phase 28

Open and recent trials

30 total, page 1 of 1

RECRUITING NA 700 participants

HEME Home Transfusion Program

Dana-Farber Cancer Institute

NCT06487247

RECRUITING NA 400 participants

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

University of Miami

NCT05745285

RECRUITING Phase 1 125 participants

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

K36 Therapeutics

NCT05651932

RECRUITING NA 60 participants

A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties

Memorial Sloan Kettering Cancer Center

NCT07052916

RECRUITING Phase 1 60 participants

Pilot Imaging Study of Leukemia

University of Oklahoma

NCT03633955

RECRUITING Phase 1 49 participants

Elotuzumab + Iberdomide + Dexamethasone Post Ide-Cel in RRMM

Omar Nadeem, MD

NCT06518551

RECRUITING Phase 1 44 participants

Phase I/II Trial of Cord Blood-Derived NK Cells Genetically Engineered With NY-ESO-1 TCR/IL-15 Cell Receptor for Relapsed/Refractory Multiple Myeloma

M.D. Anderson Cancer Center

NCT06066359

RECRUITING NA 40 participants

Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy

University of Utah

NCT07390071

RECRUITING Phase 2 39 participants

Elranatamab Post Cilta-cel in Patients With Clinical High Risk Relapsed Myeloma

H. Lee Moffitt Cancer Center and Research Institute

NCT06947083

RECRUITING Phase 1 30 participants

A Phase 1 With Extension Cohort, Single Arm, Single Center, Open Label Trial of Belantamab Mafodotin for the Treatment of High-Risk Smoldering Multiple Myeloma

M.D. Anderson Cancer Center

NCT05055063

ACTIVE NOT RECRUITING Phase 2 160 participants

Trial for Patients Not Qualifying for TT4 and TT5 Protocols Because of Prior Therapy

University of Arkansas

NCT00871013

ACTIVE NOT RECRUITING Phase 2 75 participants

Daratumumab, Carfilzomib, Lenalidomide and Low Dose Dexamethasone (DKRd) in Newly Diagnosed, Multiple Myeloma

University of Chicago

NCT03500445

ACTIVE NOT RECRUITING Early Phase 1 63 participants

PET Imaging of Cancer Patients Using 124I-PUH71: A Pilot Study

Memorial Sloan Kettering Cancer Center

NCT01269593

ACTIVE NOT RECRUITING Phase 1 54 participants

Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL

Baylor College of Medicine

NCT00881920

ACTIVE NOT RECRUITING Phase 2 41 participants

Study of Belantamab Mafodotin as Pre- and Post-autologous Stem Cell Transplant and Maintenance for Multiple Myeloma

University of Pennsylvania

NCT04680468

ACTIVE NOT RECRUITING Phase 1 30 participants

Ixazomib with Pomalidomide, Clarithromycin and Dexamethasone in Treating Patients with Multiple Myeloma

Joseph Tuscano

NCT02542657

ACTIVE NOT RECRUITING NA 20 participants

Exercise Prehabilitation Among Older Patients With Hematological Malignancies Preparing For CAR-T Cell Immunotherapy

H. Lee Moffitt Cancer Center and Research Institute

NCT05763563

COMPLETED Phase 2 264 participants

Efficacy Study of T Cell Depleted Allogeneic Non-myeloablative Stem Cell Transplant

David Rizzieri, MD

NCT00597714

COMPLETED Phase 2 176 participants

Allo Non-Myeloablative SCT Utilizing Mis-Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00580034

COMPLETED Phase 2 99 participants

Effects of Hyperbaric Oxygen (HBO) on Blood Count Recovery After Autologous Hematopoietic Stem Cell (HSPC) Transplant for Multiple Myeloma

Omar Aljitawi

NCT03398200

COMPLETED NA 90 participants

African American Cancer Clinical Trial Decisions: Testing Tailored Messages

Virginia Commonwealth University

NCT02356549

COMPLETED Phase 1 60 participants

Velcade, Trisenox, Vitamin C and Melphalan for Myeloma Patients

M.D. Anderson Cancer Center

NCT00469209

COMPLETED Phase 2 48 participants

Allo Non-myeloablative SCT Utilizing Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00578942

COMPLETED 48 participants

Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant

Duke University

NCT01904175

COMPLETED Phase 1 40 participants

Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants

Duke University

NCT00606437

COMPLETED Phase 1 30 participants

Stem Cell Transplantation for Patients With Multiple Myeloma

University of Chicago

NCT01526096

COMPLETED Early Phase 1 20 participants

Lenalidomide, Dexamethasone and MEDI-551 in Untreated Multiple Myeloma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT01861340

COMPLETED Phase 1 14 participants

Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy

H. Lee Moffitt Cancer Center and Research Institute

NCT05065866

COMPLETED Phase 1 11 participants

PET Imaging of Cancer Patients Using [18F]-SKI-249380, a Radiolabeled Dasatinib-Derivative

Memorial Sloan Kettering Cancer Center

NCT01916135

COMPLETED Phase 1 5 participants

Bone Marrow Transplantation With Specially Treated Bone Marrow in Treating Patients With Hematologic Cancer That Have Not Responded to Previous Therapy

Dana-Farber Cancer Institute

NCT00005988

Phase Distribution

PhaseTrial count
Phase 1 15
Phase 2 8

Named interventions

Most-linked intervention names on Myeloma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Dexamethasone Drug
4 trials
Melphalan Drug
3 trials
Campath Purged Non-myeloablative ASCT Drug
2 trials
Belantamab mafodotin Drug
2 trials
Stem cell re-infusion Procedure
1 trials
Physician Involvement Behavioral
1 trials
Survey Tailoring Behavioral
1 trials
EMR Tailoring Behavioral
1 trials

US sites by state

Facility locations filed on Myeloma trials. A trial with sites in several states counts in each.

Texas 6 trials
North Carolina 6 trials
New York 5 trials
Florida 5 trials
Massachusetts 4 trials
Illinois 3 trials
Pennsylvania 2 trials
New Jersey 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Myeloma page

30 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Myeloma condition card totals 30 registered trials; most-linked intervention Dexamethasone; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.