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ClinicalTrials.gov 10 recruiting now official registry

Myeloma clinical trials

Every US clinical trial registered for Myeloma — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

30 US clinical trials · 10 currently recruiting

The research picture

Myeloma has 30 registered US clinical trials, 10 of them open to new participants right now — about 33% of the total.

10
recruiting participants now
33%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
3
top sponsor: David Rizzieri, MD

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 700 participants

HEME Home Transfusion Program

Dana-Farber Cancer Institute

NCT06487247

RECRUITING NA 400 participants

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

University of Miami

NCT05745285

RECRUITING Phase 1 125 participants

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

K36 Therapeutics

NCT05651932

RECRUITING NA 60 participants

A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties

Memorial Sloan Kettering Cancer Center

NCT07052916

RECRUITING Phase 1 60 participants

Pilot Imaging Study of Leukemia

University of Oklahoma

NCT03633955

RECRUITING Phase 1 49 participants

Elotuzumab + Iberdomide + Dexamethasone Post Ide-Cel in RRMM

Omar Nadeem, MD

NCT06518551

RECRUITING Phase 1 44 participants

Phase I/II Trial of Cord Blood-Derived NK Cells Genetically Engineered With NY-ESO-1 TCR/IL-15 Cell Receptor for Relapsed/Refractory Multiple Myeloma

M.D. Anderson Cancer Center

NCT06066359

RECRUITING NA 40 participants

Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy

University of Utah

NCT07390071

RECRUITING Phase 2 39 participants

Elranatamab Post Cilta-cel in Patients With Clinical High Risk Relapsed Myeloma

H. Lee Moffitt Cancer Center and Research Institute

NCT06947083

RECRUITING Phase 1 30 participants

A Phase 1 With Extension Cohort, Single Arm, Single Center, Open Label Trial of Belantamab Mafodotin for the Treatment of High-Risk Smoldering Multiple Myeloma

M.D. Anderson Cancer Center

NCT05055063

ACTIVE NOT RECRUITING Phase 2 160 participants

Trial for Patients Not Qualifying for TT4 and TT5 Protocols Because of Prior Therapy

University of Arkansas

NCT00871013

ACTIVE NOT RECRUITING Phase 2 75 participants

Daratumumab, Carfilzomib, Lenalidomide and Low Dose Dexamethasone (DKRd) in Newly Diagnosed, Multiple Myeloma

University of Chicago

NCT03500445

ACTIVE NOT RECRUITING Early Phase 1 63 participants

PET Imaging of Cancer Patients Using 124I-PUH71: A Pilot Study

Memorial Sloan Kettering Cancer Center

NCT01269593

ACTIVE NOT RECRUITING Phase 1 54 participants

Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL

Baylor College of Medicine

NCT00881920

ACTIVE NOT RECRUITING Phase 2 41 participants

Study of Belantamab Mafodotin as Pre- and Post-autologous Stem Cell Transplant and Maintenance for Multiple Myeloma

University of Pennsylvania

NCT04680468

ACTIVE NOT RECRUITING Phase 1 30 participants

Ixazomib with Pomalidomide, Clarithromycin and Dexamethasone in Treating Patients with Multiple Myeloma

Joseph Tuscano

NCT02542657

ACTIVE NOT RECRUITING NA 20 participants

Exercise Prehabilitation Among Older Patients With Hematological Malignancies Preparing For CAR-T Cell Immunotherapy

H. Lee Moffitt Cancer Center and Research Institute

NCT05763563

COMPLETED Phase 2 264 participants

Efficacy Study of T Cell Depleted Allogeneic Non-myeloablative Stem Cell Transplant

David Rizzieri, MD

NCT00597714

COMPLETED Phase 2 176 participants

Allo Non-Myeloablative SCT Utilizing Mis-Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00580034

COMPLETED Phase 2 99 participants

Effects of Hyperbaric Oxygen (HBO) on Blood Count Recovery After Autologous Hematopoietic Stem Cell (HSPC) Transplant for Multiple Myeloma

Omar Aljitawi

NCT03398200

COMPLETED NA 90 participants

African American Cancer Clinical Trial Decisions: Testing Tailored Messages

Virginia Commonwealth University

NCT02356549

COMPLETED Phase 1 60 participants

Velcade, Trisenox, Vitamin C and Melphalan for Myeloma Patients

M.D. Anderson Cancer Center

NCT00469209

COMPLETED Phase 2 48 participants

Allo Non-myeloablative SCT Utilizing Matched Family Member Stem Cells Purged Using Campath

David Rizzieri, MD

NCT00578942

COMPLETED 48 participants

Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant

Duke University

NCT01904175

COMPLETED Phase 1 40 participants

Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants

Duke University

NCT00606437

COMPLETED Phase 1 30 participants

Stem Cell Transplantation for Patients With Multiple Myeloma

University of Chicago

NCT01526096

COMPLETED Early Phase 1 20 participants

Lenalidomide, Dexamethasone and MEDI-551 in Untreated Multiple Myeloma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT01861340

COMPLETED Phase 1 14 participants

Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy

H. Lee Moffitt Cancer Center and Research Institute

NCT05065866

COMPLETED Phase 1 11 participants

PET Imaging of Cancer Patients Using [18F]-SKI-249380, a Radiolabeled Dasatinib-Derivative

Memorial Sloan Kettering Cancer Center

NCT01916135

COMPLETED Phase 1 5 participants

Bone Marrow Transplantation With Specially Treated Bone Marrow in Treating Patients With Hematologic Cancer That Have Not Responded to Previous Therapy

Dana-Farber Cancer Institute

NCT00005988

Phase Distribution

PhaseTrial count
Phase 1 15
Phase 2 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Myeloma Trial Landscape

ClinicalTrials.gov lists 30 US studies indexed under Myeloma, and 10 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Myeloma shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 23 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Myeloma is led by David Rizzieri, MD with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 30 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Myeloma?

PlainTrial tracks 30 US clinical trials for Myeloma, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Myeloma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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