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NCT03633955 · ClinicalTrials.gov registry record · Phase 1
Pilot Imaging Study of Leukemia
A Phase 1 study of Acute Myeloid Leukemia and Myeloma, sponsored by University of Oklahoma.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
- 3
- Study locations
NCT03633955: Recruiting Phase 1 study of Acute Myeloid Leukemia and Myeloma, sponsored by University of Oklahoma.
NCT03633955 is a Phase 1 study of Acute Myeloid Leukemia and Myeloma that is actively recruiting participants, run by University of Oklahoma. The registered enrollment target is 60 participants, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (48% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03633955, a Phase 1 study of Acute Myeloid Leukemia and Myeloma, is actively recruiting participants, sponsored by University of Oklahoma.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
- 3
- Study locations
Study Summary
This is a prospective pilot study, the primary aim of which is to determine whether the presence of 18F FLT imaging signal uptake abnormalities correlate with clinically validated evidence of hematopoietic malignant disease (e.g. MRD, molecular, flow or histology) after immunotherapy and other treatments.
Primary Outcome
A proportion of patients will undergo 18F FLT imaging before and after immunotherapy or standard therapy for hematopoietic malignant disease. To detect changes in the progression of hematopoietic disease 18F FLT image scans collected pre-treatment (baseline) and post-treatment (follow-up) of patient visit at OUHSC will be compared with clinically validated evidence of hematopoietic malignant disease collected using MRD, molecular, flow and histology techniques.
Conditions Studied
Interventions
- DRUG FLT
Study Locations (3)
District of Columbia
- Children's National Health System - Washington D.C.
Georgia
- Emory University - Atlanta
Oklahoma
- University of Oklahoma Health Sciences Center - Oklahoma City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-01-19 |
| Est. Completion | 2028-04 |
| Phase | Phase 1 |
What NCT03633955 shows while recruiting
NCT03633955 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (48% lower).
The record links to 4 conditions, with Acute Myeloid Leukemia appearing as the primary indexed condition, and to 1 intervention - of which FLT is the first listed.
NCT03633955 reports a single indexed study location in District of Columbia, Georgia, Oklahoma.
Frequently Asked Questions
What is clinical trial NCT03633955 about?
NCT03633955 is a clinical study titled "Pilot Imaging Study of Leukemia". This is a prospective pilot study, the primary aim of which is to determine whether the presence of 18F FLT imaging signal uptake abnormalities correlate with clinically validated evidence of hematopoietic malignant disease (e.g. MRD, molecular, flow or histology) after immunotherapy and other treat...
What is the current status of trial NCT03633955?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2023-01-19. Estimated completion is 2028-04.
What conditions does trial NCT03633955 study?
This clinical trial studies the following conditions: Acute Myeloid Leukemia, Myeloma, Acute Lymphocytic Leukemia, Ambiguous Lineage Leukemia or Lymphoma.
What interventions are being tested in trial NCT03633955?
The interventions under investigation include: FLT (DRUG).
Who is sponsoring clinical trial NCT03633955?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03633955 being conducted?
This trial has 3 study locations across District of Columbia, Georgia, Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03633955's enrollment target sits among peer trials
60 120th of 306 higher than 180 of 306 other Acute Myeloid Leukemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Myeloid Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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