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NCT00871013 · ClinicalTrials.gov registry record · Phase 2

Trial for Patients Not Qualifying for TT4 and TT5 Protocols Because of Prior Therapy

A Phase 2 study of Myeloma, sponsored by University of Arkansas.

Active
Registry status
Phase 2
Development phase
160
Enrollment target
1
Study location

NCT00871013 is a Phase 2 study of Myeloma that is active but no longer recruiting, run by University of Arkansas. The registered enrollment target is 160 participants, above the 94-participant average among 29 other Myeloma trials with a reported enrollment target (70% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT00871013, a Phase 2 study of Myeloma, is active but no longer recruiting, sponsored by University of Arkansas.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
160 participants
Enrollment target
1
Study location

Study Summary

There have been four previous Total Therapy (TT1 through IIIB) studies for multiple myeloma at the MIRT from 1989 to present. Results have shown that participants treated on these studies had better outcomes (meaning they have lived longer and had better responses to treatment) when compared to individuals treated with standard chemotherapy. Past studies conducted at the MIRT have shown that participants presenting to MIRT who have already received treatment for myeloma tend to have shorter remissions (disappearance of signs and symptoms of myeloma) and do not survive as long as participants who come to MIRT with untreated myeloma. Researchers at MIRT think that one reason for this is may be that the myeloma cells re-grow in the time when participants are not receiving treatment because they are recovering from high-dose chemotherapy. In this study, participants will receive several chemotherapy drugs previously shown to be effective in myeloma, but in lower doses and in shorter cycles. It is hoped that by giving the drugs in this way, myeloma cells will not have time to re-grow between cycles, therefore resulting in longer remissions. This study is being done in an attempt to improve the remission rate and the survival time for participants with high-risk myeloma.

Conditions Studied

Myeloma

Interventions

  • DRUG Melphalan
  • DRUG Cisplatin
  • DRUG Dexamethasone
  • DRUG Thalidomide
  • DRUG Velcade

Study Locations (1)

Arkansas

  • University of Arkansas for Medical Sciences - Little Rock

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2009-03
Est. Completion 2026-12
Phase Phase 2

Sponsor

University of Arkansas

318 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00871013

The ClinicalTrials.gov registry entry for NCT00871013 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 94-participant average among 29 other Myeloma trials with a reported enrollment target (70% higher). The listed sponsor is University of Arkansas, which has 318 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Myeloma appearing as the primary indexed condition, and to 5 interventions - of which Melphalan is the first listed.

NCT00871013 reports 1 study location spanning 1 distinct geographic area - top geographies include Arkansas.

Frequently Asked Questions

What is clinical trial NCT00871013 about?

NCT00871013 is a clinical study titled "Trial for Patients Not Qualifying for TT4 and TT5 Protocols Because of Prior Therapy". There have been four previous Total Therapy (TT1 through IIIB) studies for multiple myeloma at the MIRT from 1989 to present. Results have shown that participants treated on these studies had better outcomes (meaning they have lived longer and had better responses to treatment) when compared to indi...

What is the current status of trial NCT00871013?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 160 participants. The study started on 2009-03. Estimated completion is 2026-12.

What conditions does trial NCT00871013 study?

This clinical trial studies the following conditions: Myeloma.

What interventions are being tested in trial NCT00871013?

The interventions under investigation include: Melphalan (DRUG), Cisplatin (DRUG), Dexamethasone (DRUG), Thalidomide (DRUG), Velcade (DRUG).

Who is sponsoring clinical trial NCT00871013?

This trial is sponsored by University of Arkansas, which has 318 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00871013 being conducted?

This trial has 1 study location across Arkansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.