Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Metabolic Syndrome: full-pipeline trial registry
28 of 104 indexed Metabolic Syndrome trials are currently recruiting.
Corpus placement: #129 of 28,707 conditions by registered trial count.
104 US clinical trials · 28 currently recruiting · #129 of 28,707 conditions by registered trial count
Metabolic Syndrome: 104 US clinical trials tracked, 28 recruiting.
Metabolic Syndrome is the subject of 104 registered US clinical trials on ClinicalTrials.gov, 28 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Davis, running 5 of these trials.
Enrollment posture brief
Registry condition metabolic-syndrome
OPEN 28 | RECR 27% | LATE 7 | EARLY 9 | RANK #129 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Cancer Survivor (27% recruiting · 26 trials)
Metabolic Syndrome lists 28 open slots (27% of 104 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Metabolic Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Metabolic Syndrome is recruiting below its size-band peers.
28 of 104 indexed trials (26.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Metabolic Syndrome trials is spread across many organizations.
University of California, Davis accounts for 5 of 104 trials (4.8%). 80 distinct sponsors appear on at least one study for this condition label.
-
Most Metabolic Syndrome trials plan to enrol fewer than 100 people.
Median target enrolment is 55 among the 103 trials that report a genuine target (sentinel values excluded). 70 of those (68%) plan for fewer than 100 participants.
-
Metabolic Syndrome research is mostly interventional.
88 interventional and 16 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
104 total, page 2 of 3
VIsceral Fat Reduction Assessed by CT-scan On RImonabAnt
Sanofi
NCT00299325
A Simple Dietary Message to Improve Dietary Quality for Metabolic Syndrome
University of Massachusetts, Worcester
NCT00911885
A Study of the Function of Hormones Present In Taste Buds
National Institute on Aging (NIA)
NCT00233298
A Web-based Approach to Treating Cardiovascular Disease Risk in Employees With Metabolic Syndrome
Baptist Health South Florida
NCT01912209
Chronic Inflammation and Exercise Responsiveness
Mayo Clinic
NCT02732509
Metformin in Kidney Disease
VA Office of Research and Development
NCT02252081
Canola Oil Multi-Centre Intervention Trial II
University of Manitoba
NCT02029833
Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen
Thomas Jefferson University
NCT03646370
The Role of Leptin Receptors in NASH
University of California, Davis
NCT00583999
Metabolic Syndrome in PCOS: Precursors and Interventions
Northwestern University
NCT00442689
Taste Perception and Chronic Disease Risk
Tufts University
NCT01023906
Improving Metabolic Health in Patients With Diastolic Dysfunction
University of Texas Southwestern Medical Center
NCT03448185
Nutrition Outreach and Understanding: Research In Serving Hearts Through Healthy Eating And Tailored Support
Amanda Shallcross
NCT06460272
The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis (DAIRY Study)
Fred Hutchinson Cancer Center
NCT02663544
A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overweight Patients With High Blood Pressure to Respond to Insulin
Daiichi Sankyo
NCT00185094
Soybean Oil Trial of cArdiovascular Risk
USDA Beltsville Human Nutrition Research Center
NCT02404207
Effect of Resvida, a Comparison With Calorie Restriction Regimen
Washington University School of Medicine
NCT00823381
Healthy Liver - Healthy Brain
University of Texas at Austin
NCT05216796
Grains Reduce Adiposity and Improve Nutrition Study
Penn State University
NCT00924521
The Health-Promoting Role of Pears in Men and Women With Metabolic Syndrome
Florida State University
NCT02228837
Cardiac Autonomic Neuropathy in Patients With Metabolic Syndrome
University of Michigan
NCT00907127
Comparative Effects of Chronic Treatment With Olanzapine and Risperidone on Glucose and Lipid Metabolism
Nathan Kline Institute for Psychiatric Research
NCT00287820
Gut-level Antiinflammatory Activities of Green Tea in Metabolic Syndrome
Ohio State University
NCT03973996
P20 Extending Sleep to Reverse Metabolic Syndrome
NYU Langone Health
NCT03596983
Fetuin-A Phosphorylation Status in Insulin Resistance and Metabolic Syndrome
Auburn University
NCT03478046
Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics
University of Alabama at Birmingham
NCT04392284
The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome
Christos Mantzoros
NCT00525629
Short-term Sugary Beverage Consumption on Glucose Control and Cardiovascular Disease Risk Factors
Kansas State University
NCT04118257
12 Weeks of Resistance Band Exercise Impacts on Metabolic Syndrome Progression in Postmenopausal Women
Pusan National University
NCT04014686
Bioactive Plant Foods: Effects on Functional Bioavailability and Genomic Stability
Tufts University
NCT00963118
Effects of Fish Oils on Inflammation and Insulin Resistance
Philip Kern
NCT00579436
Effects of Consuming Sugar-Sweetened Beverages With Meals for 10 Weeks
University of California, Davis
NCT01165853
The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction
Milton S. Hershey Medical Center
NCT00284960
Resveratrol and the Metabolic Syndrome
Rockefeller University
NCT01714102
The BANGALORE Study; Combination of Berberine, Lipoic Acid, and Picrorhiza
Carmel Biosciences
NCT01696448
Spinal Cord Injury Exercise and Nutrition Conceptual Engagement
University of Miami
NCT03495986
Women's Lifestyle Balance Study
University of California, San Francisco
NCT03184337
Impact of 60 Days Powdered Tart Cherry Supplementation on Metabolic Syndrome
Ohio University
NCT05614947
Sleep Chatbot Intervention for Emerging Black/African American Adults
University of Delaware
NCT05956886
Role of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Inflammation and Lipids
Tufts University
NCT02670382
Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness
Stanford University
NCT03935854
Vasoprotective Activities of Low-Fat Milk in Individuals With Metabolic Syndrome
University of Connecticut
NCT01411293
Exercise-Induced Epigenetic Modifications in Obese Aging Women
University of Georgia
NCT01977885
Effect of Diet-induced Weight Loss on HIV-associated Metabolic Syndrome
Washington University School of Medicine
NCT00857298
Effects of Diet Interventions on Monocytes in Metabolic Syndrome
Baylor College of Medicine
NCT03591588
Effect of Vestibular Stimulation on Fat Consumption and Energy Expenditure as Assessed Using Indirect Calorimetry
University of California, San Diego
NCT03138382
Metabolic Effects of Pulse Consumption on Biomarkers in Adults With Type 2 Diabetes or Met Syn
Iowa State University
NCT05145998
Impact of Metabolic Flexibility on Changes in Metabolic Health
Pennington Biomedical Research Center
NCT06340321
Virtual Teaching Kitchen
Boston University
NCT04509206
The Effect of Whole Beans on Inflammation and Satiety
University of California, Davis
NCT01190384
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 6 |
| Phase 3 | 1 |
| Phase 4 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on Metabolic Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Metabolic Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Metabolic Syndrome page
104 registered trials, 28 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 28 Metabolic Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of California, Davis sponsors the most Metabolic Syndrome trials on record, review their full trial history before evaluating a specific study. See University of California, Davis's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metabolic Syndrome condition card totals 104 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.