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NCT00583999 · ClinicalTrials.gov registry record
The Role of Leptin Receptors in NASH
A clinical trial of Metabolic Syndrome and Nonalcoholic Steatohepatitis, sponsored by University of California, Davis.
- Completed
- Registry status
- 104
- Enrollment target
- 1
- Study location
NCT00583999: Completed study of Metabolic Syndrome and Nonalcoholic Steatohepatitis, sponsored by University of California, Davis.
NCT00583999 is a study of Metabolic Syndrome and Nonalcoholic Steatohepatitis that has completed, run by University of California, Davis. The registered enrollment target is 104 participants, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00583999, a study of Metabolic Syndrome and Nonalcoholic Steatohepatitis, has completed, sponsored by University of California, Davis.
- COMPLETED
- Registry status
- 104 participants
- Enrollment target
- 1
- Study location
Study Summary
NAFLD is a spectrum of liver diseases associated with varying degrees of hepatic steatosis, inflammation, and in some cases, fibrosis. NAFLD is a common observation in all demographics, but the prevalence of NAFLD and nonalcoholic steatohepatitis (NASH) is especially high in the morbidly obese population. Leptin is a cytokine that is encoded by the ob gene and primarily secreted by adipose tissue. The production of serum leptin increases with progressive obesity. Because of this observation, there has been significant interest in potential role of leptin in NAFLD. Our hypothesis is that we will find increased hepatic leptin and leptin receptor expression as the degree of hepatic injury worsens in NAFLD.
Conditions Studied
Interventions
- OTHER no interventions, only regular blood-draw
Study Locations (1)
California
- UC Davis Medical Center - Sacramento
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 104 participants |
| Start Date | 2006-01 |
| Est. Completion | 2009-06 |
What the finished NCT00583999 record still lists
NCT00583999 is an observational study that tracks outcomes without assigning an intervention. The registered 104 participants enrollment target is mid-sized for trials with a published cap, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Metabolic Syndrome appearing as the primary indexed condition, and to 1 intervention - of which no interventions, only regular blood-draw is the first listed.
NCT00583999 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00583999 about?
NCT00583999 is a clinical study titled "The Role of Leptin Receptors in NASH". NAFLD is a spectrum of liver diseases associated with varying degrees of hepatic steatosis, inflammation, and in some cases, fibrosis. NAFLD is a common observation in all demographics, but the prevalence of NAFLD and nonalcoholic steatohepatitis (NASH) is especially high in the morbidly obese popul...
What is the current status of trial NCT00583999?
This trial is currently completed. The enrollment target is 104 participants. The study started on 2006-01. Estimated completion is 2009-06.
What conditions does trial NCT00583999 study?
This clinical trial studies the following conditions: Metabolic Syndrome, Nonalcoholic Steatohepatitis.
What interventions are being tested in trial NCT00583999?
The interventions under investigation include: no interventions, only regular blood-draw (OTHER).
Who is sponsoring clinical trial NCT00583999?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00583999 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00583999's enrollment target sits among peer trials
104 31st of 102 higher than 72 of 102 other Metabolic Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metabolic Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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