Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Autism

Open-data reference.

105 US clinical trials · 49 currently recruiting

Active & Recent Trials

RECRUITING 5,000 participants

The Neurodevelopmental and Behavioral Phenotyping Screening Protocol

National Institute of Mental Health (NIMH)

NCT00271622

RECRUITING 2,120 participants

Screening for Autism in 9-Month-Olds by Measuring Social Visual Engagement

Emory University

NCT05916430

RECRUITING NA 600 participants

Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism

University of California, Davis

NCT06005285

RECRUITING 500 participants

The FBRI VTC Neuromotor Research Clinic

Virginia Polytechnic Institute and State University

NCT03325946

RECRUITING 350 participants

SenseToKnow Autism Screening Device Validation Study

Duke University

NCT05874466

RECRUITING NA 300 participants

Early Diagnostic Response Model (EDRM)

Emory University

NCT05419895

RECRUITING NA 297 participants

COMPASS Across Settings (CAST) for Improving Transition Outcomes for Students With ASD

Ball State University

NCT06309160

RECRUITING NA 270 participants

Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism

University of Washington

NCT06208722

RECRUITING NA 224 participants

Improving Academic and Social Functioning in Middle-Schoolers With Autism

Children's Hospital Medical Center, Cincinnati

NCT06705907

RECRUITING NA 200 participants

Meeting the Needs of Young Hispanic Autistic Children

The University of Texas at Dallas

NCT06733584

RECRUITING Phase 4 196 participants

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

Gagan Joshi

NCT06853665

RECRUITING NA 188 participants

Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)

Hugo W. Moser Research Institute at Kennedy Krieger

NCT05176808

RECRUITING Phase 2 184 participants

Optimizing Outcomes for Young Autistic Children

Northwestern University

NCT05926687

RECRUITING 170 participants

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

Boston Children's Hospital

NCT02461446

RECRUITING NA 150 participants

Family, Responsibility, Education, Support, and Health for Families With a Child With Autism

University of California, San Diego

NCT05741840

RECRUITING NA 139 participants

Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety

Baylor College of Medicine

NCT06537128

RECRUITING NA 120 participants

Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism

Stanford University

NCT04899544

RECRUITING NA 120 participants

"Opt-In" Early Intervention Program for Children Waiting to Receive an Autism Diagnosis

Drexel University

NCT07081724

RECRUITING Phase 1 100 participants

Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study

Adia Med of Winter Park

NCT07304440

RECRUITING NA 100 participants

CBT for Youth With Autism and Emotional/Behavioral Needs in Community Care Settings

University of California, Los Angeles

NCT05031364

RECRUITING NA 100 participants

Word Learning From Parentese in Autistic Children

The University of Texas at Dallas

NCT06649916

RECRUITING NA 100 participants

Use of Eye Tracking to Aid in Autism Risk Detection

Indiana University

NCT06471504

RECRUITING NA 80 participants

Cerebellum and Autism: Regional Specialization for Social and Executive Functions

American University

NCT05396352

RECRUITING NA 80 participants

Evaluating Pathways Mutual Gaze Protocol on Social Skills in Young Children Suspected of Autism

The University of Texas at Dallas

NCT06596226

RECRUITING NA 80 participants

Achieving Steady Work Among Adults With Autism Through Specialized Employment Program

Lawrence Fung

NCT04107064

RECRUITING NA 80 participants

Evaluating Georgia Part C Implementation Outcomes

Emory University

NCT07148258

RECRUITING NA 76 participants

PRT for Adolescents With High Functioning Autism

Stanford University

NCT05987761

RECRUITING NA 67 participants

Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD

Stanford University

NCT04532424

RECRUITING Phase 2 60 participants

The Impact of a Virtual Magic Trick Training Program

University of Alabama at Birmingham

NCT05664841

RECRUITING NA 44 participants

Online Pivotal Response Treatment Training in Autism Spectrum Disorder

Stanford University

NCT06523387

RECRUITING NA 44 participants

Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth

Stanford University

NCT06362733

RECRUITING NA 40 participants

Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder

University of Pennsylvania

NCT06859918

RECRUITING NA 40 participants

Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers

Vanderbilt University Medical Center

NCT05880225

RECRUITING NA 36 participants

Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism

Stanford University

NCT03583684

RECRUITING NA 30 participants

A Strength-Based Employment Maintenance Program for Individuals on the Autism Spectrum

Kessler Foundation

NCT06255925

RECRUITING NA 30 participants

Optimizing Dimensions of Reinforcement

Auburn University

NCT07137273

RECRUITING NA 30 participants

Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children

Stanford University

NCT06472115

RECRUITING NA 28 participants

In-Person Mindfulness-based Intervention for Adolescents with Autism Spectrum Disorder and Their Caregivers

Southwest Autism Research & Resource Center

NCT06577623

RECRUITING Phase 2 26 participants

Trial of Zolpidem for Sleep in Children With Autism

Stanford University

NCT05540574

RECRUITING Phase 2 26 participants

Trial of Diphenhydramine for Sleep in Children With Autism

Stanford University

NCT05501678

RECRUITING Phase 2 26 participants

Trial of Suvorexant for Sleep in Children With Autism

Stanford University

NCT05546554

RECRUITING Phase 2 25 participants

A Study of Esomeprazole in Children With Autism

Stanford University

NCT03866668

RECRUITING NA 25 participants

Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism

Stanford University

NCT06627205

RECRUITING NA 25 participants

Biomarkers Research in Anxiety for Validation and Efficacy

Boston Children's Hospital

NCT06221176

RECRUITING NA 24 participants

TF-CBT for Autistic Youth Pilot Implementation - Open Pilot

Dartmouth-Hitchcock Medical Center

NCT07420478

RECRUITING NA 20 participants

Better Social, Emotional Communication, Healthy Relationship and ASD Accommodation Skills: Emotional Intelligence ("EQ") Training for Autistic People and ASD Accommodation Training for People Who Care

Kairon Connect, PBC

NCT07315867

RECRUITING NA 20 participants

Project VOICES: Vocal Optimization in Children Elevating the Spectrum

Vanderbilt University Medical Center

NCT06875843

RECRUITING NA 12 participants

FLIGHT - Autism: Education and Health Coaching Program Focused on Modifiable Lifestyle Factors for Parents

Documenting Hope Project

NCT07375537

RECRUITING NA 10 participants

The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

University of Pittsburgh

NCT06386029

ACTIVE NOT RECRUITING Phase 3 405 participants

An Open Label Study of CM-AT for the Treatment of Children With Autism

Curemark

NCT02649959

ACTIVE NOT RECRUITING 297 participants

Mitochondrial Dysfunction in Autism Spectrum Disorder

University of Arkansas

NCT02000284

ACTIVE NOT RECRUITING 240 participants

Genetic Contributions to Autism Spectrum Disorders

Boston Children's Hospital

NCT01160783

ACTIVE NOT RECRUITING NA 200 participants

Project AFECT (Autism Family Empowerment Coaching and Training Program)

Stanford University

NCT05910502

ACTIVE NOT RECRUITING NA 132 participants

Developing Treatment, Treatment Validation and Treatment Scope in the Setting of an Autism Clinical Trial

Rutgers, The State University of New Jersey

NCT01260961

ACTIVE NOT RECRUITING NA 75 participants

A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism

Stanford University

NCT03778827

ACTIVE NOT RECRUITING Phase 2 48 participants

Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism

Rutgers, The State University of New Jersey

NCT02677051

ACTIVE NOT RECRUITING Phase 2 42 participants

Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism

University of California, San Diego

NCT04517799

ACTIVE NOT RECRUITING NA 40 participants

The Effectiveness of an Autistic-delivered Peer-support Intervention for Autistic Adults: Community Autism Peer Specialist (CAPS) Program

Drexel University

NCT05702658

ACTIVE NOT RECRUITING Phase 2 40 participants

Pilot Trial of Pregnenolone in Autism

Stanford University

NCT02627508

ACTIVE NOT RECRUITING NA 24 participants

Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder

Children's Hospital Medical Center, Cincinnati

NCT06670040

ACTIVE NOT RECRUITING NA 15 participants

Adapting BA for Minimally Verbal Autistic Adults

Rutgers, The State University of New Jersey

NCT06064422

COMPLETED Phase 3 702 participants

Pediatric Open-Label Extension Study

Sumitomo Pharma America

NCT01914393

COMPLETED NA 541 participants

A Lead-in Study Evaluating Efficacy of GuessWhat Mobile App Therapy for Children With Autism

Stanford University

NCT04739982

COMPLETED Phase 2 479 participants

Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine

Forest Laboratories

NCT01592747

COMPLETED 324 participants

Predictors of Caregiver Adaptation to Pervasive Developmental Disorders

National Human Genome Research Institute (NHGRI)

NCT00496210

COMPLETED 322 participants

Exome Sequencing in Autistic Spectrum Disorder

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT01059201

COMPLETED NA 250 participants

Autism Intervention Research Network for Behavioral Health (AIR-B II): Deployment Into Elementary Schools

Health Resources and Services Administration (HRSA)

NCT01724047

COMPLETED NA 214 participants

Psychotherapy for Anxiety in Children With Autism Spectrum Disorder

University of South Florida

NCT02028247

COMPLETED NA 192 participants

Adaptive Interventions for Minimally Verbal Children With ASD in the Community

University of California, Los Angeles

NCT01751698

COMPLETED Phase 3 182 participants

A Trial of CM-AT in Children With Autism

Curemark

NCT00881452

COMPLETED Phase 2 180 participants

Cord Blood Infusion for Children With Autism Spectrum Disorder

Joanne Kurtzberg, MD

NCT02847182

COMPLETED Phase 2 137 participants

hCT-MSC in Children With Autism Spectrum Disorder

Joanne Kurtzberg, MD

NCT04089579

COMPLETED NA 118 participants

Intensive Intervention for Toddlers With Autism (EARLY STEPS)

University of California, Davis

NCT00698997

COMPLETED NA 112 participants

Randomized Controlled Trial of the P.L.A.Y. (Play and Language for Autistic Youngsters) Project Intervention for Autism

Richard Solomon MD

NCT01768806

COMPLETED Phase 2 102 participants

Open-label Study of Safety and Tolerability of Memantine in Children With Autism

Forest Laboratories

NCT01999894

COMPLETED Phase 4 96 participants

A Study of the Effectiveness and Safety of Two Doses of Risperidone in the Treatment of Children and Adolescents With Autistic Disorder

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

NCT00576732

COMPLETED 83 participants

Show Me to Help Me

Akron Children's Hospital

NCT01311596

COMPLETED 77 participants

Study of Toddlers With Language Delay

National Institute of Mental Health (NIMH)

NCT01339767

COMPLETED NA 64 participants

Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism

Emory University

NCT03152383

COMPLETED Phase 1 60 participants

An Autism Study Using Nambudripad's Food Allergy Elimination Treatments

Nambudripad's Allergy Research Foundation

NCT00247156

COMPLETED Phase 2 58 participants

A 12-Week Crossover Study to Assess the Efficacy, Safety and Tolerability of L1-79 in Subjects Aged 12-21 Years With Autism Spectrum Disorder

Yamo Pharmaceuticals

NCT05067582

COMPLETED NA 48 participants

Adapting an Advocacy Services Intervention for Latinx Families of Transition-aged Youth With Autism Spectrum Disorder

Vanderbilt University

NCT06207149

COMPLETED NA 45 participants

Randomized Study of Fluoxetine in Children and Adolescents With Autism

Icahn School of Medicine at Mount Sinai

NCT00004486

COMPLETED Phase 2 45 participants

Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders

University of South Florida

NCT01178385

COMPLETED NA 44 participants

Services to Enhance Social Functioning in Adults With Autism Spectrum Disorders

University of Pennsylvania

NCT04788537

COMPLETED Phase 2 44 participants

Sulforaphane-rich Broccoli Sprout Extract for Autism

Andrew Zimmerman

NCT01474993

COMPLETED NA 44 participants

Social Cognition and Interaction Training for Autism

University of North Carolina, Chapel Hill

NCT02382172

COMPLETED Phase 2 41 participants

Risperidone Treatment In Children With Autism Spectrum Disorder And High Levels Of Repetitive Behavior

University of California, Los Angeles

NCT01171937

COMPLETED NA 38 participants

Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD

Massachusetts General Hospital

NCT04569058

COMPLETED Phase 2 30 participants

Autologous Cord Blood Stem Cells for Autism

Sutter Health

NCT01638819

COMPLETED Phase 2 27 participants

Divalproex Sodium vs. Placebo in Childhood/Adolescent Autism

Montefiore Medical Center

NCT00211757

COMPLETED Phase 3 25 participants

Study of Paliperidone ER in Adolescents and Young Adults With Autism

Indiana University School of Medicine

NCT00549562

COMPLETED Phase 2 24 participants

Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children

The University of Texas Health Science Center, Houston

NCT00178503

COMPLETED 20 participants

MENTIS Personal Health Record Rapid Pilot Research Deployment and Evaluation

Northeastern University

NCT02090491

COMPLETED 17 participants

In Vivo Imaging of Therapeutic Electric Current Flow

University of Florida

NCT02453763

COMPLETED NA 17 participants

Coaching Children With Anxiety and Autism Through Telehealth

Medical University of South Carolina

NCT05588570

COMPLETED Phase 3 16 participants

A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms

University of Oklahoma

NCT00541346

COMPLETED NA 16 participants

Effect of Parenting With Positive Interven on Comm Inclusion for Military Connected and Dependents With Autism

Virginia Commonwealth University

NCT05580432

COMPLETED Phase 2 14 participants

Testing a Novel Speech Intervention in Minimally Verbal Children With Autism Spectrum Disorder (ASD)

Beth Israel Deaconess Medical Center

NCT03015272

COMPLETED Phase 2 14 participants

An Open-Label Trial of Aripiprazole in Autism Spectrum Disorders

Cambridge Health Alliance

NCT00308074

Phase Distribution

PhaseTrial count
Early Phase 1 3
Phase 2 23
Phase 3 5
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Autism Trial Landscape

ClinicalTrials.gov lists 105 US studies indexed under Autism, and 49 of those are currently open to recruitment — roughly 47% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Autism shows 8 late-stage studies (Phase 3 and Phase 4 combined) alongside 26 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Autism is led by Stanford University with 16 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Autism?

PlainTrial tracks 105 US clinical trials for Autism, of which 49 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Autism?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →