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ClinicalTrials.gov 49 recruiting now early-phase tilt #125 of 28,707 conditions

Autism: early-phase trial registry

49 of 105 indexed Autism trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #125 of 28,707 conditions by registered trial count.

105 US clinical trials · 49 currently recruiting · #125 of 28,707 conditions by registered trial count

Autism: 105 US clinical trials tracked, 49 recruiting.

Autism is the subject of 105 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is Stanford University, running 16 of these trials.

Enrollment posture brief

Registry condition autism

OPEN 49 | RECR 47% | LATE 8 | EARLY 26 | RANK #125 | SPON 16

Nearest open-share peer: Bipolar II Disorder (47% recruiting · 15 trials)

Autism (this)47%Cognitive Impairment43.4%Migraine38.1%Hematopoietic and Lymphoid C33.3%Schizoaffective Disorder29.5%
Open-enrollment share among volume-matched conditions near Autism

Autism lists 49 open slots (47% of 105 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Autism on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Autism is recruiting above its size-band peers.

    49 of 105 indexed trials (46.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Autism research.

    Stanford University accounts for 16 of 105 trials (15.2%). 66 distinct sponsors appear on at least one study for this condition label.

  3. Most Autism trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 105 trials that report a genuine target (sentinel values excluded). 64 of those (61%) plan for fewer than 100 participants.

  4. Autism research is mostly interventional.

    92 interventional and 13 observational studies make up this index (87.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 223Phase 35Phase 43

Open and recent trials

105 total, page 1 of 3

RECRUITING 5,000 participants

The Neurodevelopmental and Behavioral Phenotyping Screening Protocol

National Institute of Mental Health (NIMH)

NCT00271622

RECRUITING 2,120 participants

Screening for Autism in 9-Month-Olds by Measuring Social Visual Engagement

Emory University

NCT05916430

RECRUITING NA 600 participants

Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism

University of California, Davis

NCT06005285

RECRUITING 500 participants

The FBRI VTC Neuromotor Research Clinic

Virginia Polytechnic Institute and State University

NCT03325946

RECRUITING 350 participants

SenseToKnow Autism Screening Device Validation Study

Duke University

NCT05874466

RECRUITING NA 300 participants

Early Diagnostic Response Model (EDRM)

Emory University

NCT05419895

RECRUITING NA 297 participants

COMPASS Across Settings (CAST) for Improving Transition Outcomes for Students With ASD

Ball State University

NCT06309160

RECRUITING NA 270 participants

Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism

University of Washington

NCT06208722

RECRUITING NA 224 participants

Improving Academic and Social Functioning in Middle-Schoolers With Autism

Children's Hospital Medical Center, Cincinnati

NCT06705907

RECRUITING NA 200 participants

Meeting the Needs of Young Hispanic Autistic Children

The University of Texas at Dallas

NCT06733584

RECRUITING Phase 4 196 participants

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

Gagan Joshi

NCT06853665

RECRUITING NA 188 participants

Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)

Hugo W. Moser Research Institute at Kennedy Krieger

NCT05176808

RECRUITING Phase 2 184 participants

Optimizing Outcomes for Young Autistic Children

Northwestern University

NCT05926687

RECRUITING 170 participants

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

Boston Children's Hospital

NCT02461446

RECRUITING NA 150 participants

Family, Responsibility, Education, Support, and Health for Families With a Child With Autism

University of California, San Diego

NCT05741840

RECRUITING NA 139 participants

Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety

Baylor College of Medicine

NCT06537128

RECRUITING NA 120 participants

Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism

Stanford University

NCT04899544

RECRUITING NA 120 participants

"Opt-In" Early Intervention Program for Children Waiting to Receive an Autism Diagnosis

Drexel University

NCT07081724

RECRUITING Phase 1 100 participants

Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study

Adia Med of Winter Park

NCT07304440

RECRUITING NA 100 participants

CBT for Youth With Autism and Emotional/Behavioral Needs in Community Care Settings

University of California, Los Angeles

NCT05031364

RECRUITING NA 100 participants

Word Learning From Parentese in Autistic Children

The University of Texas at Dallas

NCT06649916

RECRUITING NA 100 participants

Use of Eye Tracking to Aid in Autism Risk Detection

Indiana University

NCT06471504

RECRUITING NA 80 participants

Cerebellum and Autism: Regional Specialization for Social and Executive Functions

American University

NCT05396352

RECRUITING NA 80 participants

Evaluating Pathways Mutual Gaze Protocol on Social Skills in Young Children Suspected of Autism

The University of Texas at Dallas

NCT06596226

RECRUITING NA 80 participants

Achieving Steady Work Among Adults With Autism Through Specialized Employment Program

Lawrence Fung

NCT04107064

RECRUITING NA 80 participants

Evaluating Georgia Part C Implementation Outcomes

Emory University

NCT07148258

RECRUITING NA 76 participants

PRT for Adolescents With High Functioning Autism

Stanford University

NCT05987761

RECRUITING NA 67 participants

Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD

Stanford University

NCT04532424

RECRUITING Phase 2 60 participants

The Impact of a Virtual Magic Trick Training Program

University of Alabama at Birmingham

NCT05664841

RECRUITING NA 44 participants

Online Pivotal Response Treatment Training in Autism Spectrum Disorder

Stanford University

NCT06523387

RECRUITING NA 44 participants

Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth

Stanford University

NCT06362733

RECRUITING NA 40 participants

Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder

University of Pennsylvania

NCT06859918

RECRUITING NA 40 participants

Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers

Vanderbilt University Medical Center

NCT05880225

RECRUITING NA 36 participants

Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism

Stanford University

NCT03583684

RECRUITING NA 30 participants

A Strength-Based Employment Maintenance Program for Individuals on the Autism Spectrum

Kessler Foundation

NCT06255925

RECRUITING NA 30 participants

Optimizing Dimensions of Reinforcement

Auburn University

NCT07137273

RECRUITING NA 30 participants

Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children

Stanford University

NCT06472115

RECRUITING NA 28 participants

In-Person Mindfulness-based Intervention for Adolescents with Autism Spectrum Disorder and Their Caregivers

Southwest Autism Research & Resource Center

NCT06577623

RECRUITING Phase 2 26 participants

Trial of Zolpidem for Sleep in Children With Autism

Stanford University

NCT05540574

RECRUITING Phase 2 26 participants

Trial of Diphenhydramine for Sleep in Children With Autism

Stanford University

NCT05501678

RECRUITING Phase 2 26 participants

Trial of Suvorexant for Sleep in Children With Autism

Stanford University

NCT05546554

RECRUITING Phase 2 25 participants

A Study of Esomeprazole in Children With Autism

Stanford University

NCT03866668

RECRUITING NA 25 participants

Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism

Stanford University

NCT06627205

RECRUITING NA 25 participants

Biomarkers Research in Anxiety for Validation and Efficacy

Boston Children's Hospital

NCT06221176

RECRUITING NA 24 participants

TF-CBT for Autistic Youth Pilot Implementation - Open Pilot

Dartmouth-Hitchcock Medical Center

NCT07420478

RECRUITING NA 20 participants

Better Social, Emotional Communication, Healthy Relationship and ASD Accommodation Skills: Emotional Intelligence ("EQ") Training for Autistic People and ASD Accommodation Training for People Who Care

Kairon Connect, PBC

NCT07315867

RECRUITING NA 20 participants

Project VOICES: Vocal Optimization in Children Elevating the Spectrum

Vanderbilt University Medical Center

NCT06875843

RECRUITING NA 12 participants

FLIGHT - Autism: Education and Health Coaching Program Focused on Modifiable Lifestyle Factors for Parents

Documenting Hope Project

NCT07375537

RECRUITING NA 10 participants

The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

University of Pittsburgh

NCT06386029

ACTIVE NOT RECRUITING Phase 3 405 participants

An Open Label Study of CM-AT for the Treatment of Children With Autism

Curemark

NCT02649959

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Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 23
Phase 3 5
Phase 4 3

Named interventions

Most-linked intervention names on Autism records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
11 trials
Treatment as Usual Behavioral
3 trials
Aripiprazole Drug
2 trials
CM-AT Drug
2 trials
Placebo Biological
2 trials
Transcranial direct current stimulation Device
2 trials
Cord Tissue Mesenchymal Stromal Cells Biological
1 trials
Icons Other
1 trials

US sites by state

Facility locations filed on Autism trials. A trial with sites in several states counts in each.

California 35 trials
New York 12 trials
Pennsylvania 10 trials
New Jersey 10 trials
Florida 10 trials
Ohio 9 trials
Massachusetts 9 trials
Texas 8 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Autism page

105 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Autism condition card totals 105 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.