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Autism
Open-data reference.
105 US clinical trials · 49 currently recruiting
Active & Recent Trials
The Neurodevelopmental and Behavioral Phenotyping Screening Protocol
National Institute of Mental Health (NIMH)
NCT00271622
Screening for Autism in 9-Month-Olds by Measuring Social Visual Engagement
Emory University
NCT05916430
Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism
University of California, Davis
NCT06005285
The FBRI VTC Neuromotor Research Clinic
Virginia Polytechnic Institute and State University
NCT03325946
SenseToKnow Autism Screening Device Validation Study
Duke University
NCT05874466
Early Diagnostic Response Model (EDRM)
Emory University
NCT05419895
COMPASS Across Settings (CAST) for Improving Transition Outcomes for Students With ASD
Ball State University
NCT06309160
Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
University of Washington
NCT06208722
Improving Academic and Social Functioning in Middle-Schoolers With Autism
Children's Hospital Medical Center, Cincinnati
NCT06705907
Meeting the Needs of Young Hispanic Autistic Children
The University of Texas at Dallas
NCT06733584
The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine
Gagan Joshi
NCT06853665
Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)
Hugo W. Moser Research Institute at Kennedy Krieger
NCT05176808
Optimizing Outcomes for Young Autistic Children
Northwestern University
NCT05926687
Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
Boston Children's Hospital
NCT02461446
Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
University of California, San Diego
NCT05741840
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Baylor College of Medicine
NCT06537128
Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism
Stanford University
NCT04899544
"Opt-In" Early Intervention Program for Children Waiting to Receive an Autism Diagnosis
Drexel University
NCT07081724
Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study
Adia Med of Winter Park
NCT07304440
CBT for Youth With Autism and Emotional/Behavioral Needs in Community Care Settings
University of California, Los Angeles
NCT05031364
Word Learning From Parentese in Autistic Children
The University of Texas at Dallas
NCT06649916
Use of Eye Tracking to Aid in Autism Risk Detection
Indiana University
NCT06471504
Cerebellum and Autism: Regional Specialization for Social and Executive Functions
American University
NCT05396352
Evaluating Pathways Mutual Gaze Protocol on Social Skills in Young Children Suspected of Autism
The University of Texas at Dallas
NCT06596226
Achieving Steady Work Among Adults With Autism Through Specialized Employment Program
Lawrence Fung
NCT04107064
Evaluating Georgia Part C Implementation Outcomes
Emory University
NCT07148258
PRT for Adolescents With High Functioning Autism
Stanford University
NCT05987761
Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD
Stanford University
NCT04532424
The Impact of a Virtual Magic Trick Training Program
University of Alabama at Birmingham
NCT05664841
Online Pivotal Response Treatment Training in Autism Spectrum Disorder
Stanford University
NCT06523387
Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth
Stanford University
NCT06362733
Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder
University of Pennsylvania
NCT06859918
Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers
Vanderbilt University Medical Center
NCT05880225
Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism
Stanford University
NCT03583684
A Strength-Based Employment Maintenance Program for Individuals on the Autism Spectrum
Kessler Foundation
NCT06255925
Optimizing Dimensions of Reinforcement
Auburn University
NCT07137273
Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children
Stanford University
NCT06472115
In-Person Mindfulness-based Intervention for Adolescents with Autism Spectrum Disorder and Their Caregivers
Southwest Autism Research & Resource Center
NCT06577623
Trial of Zolpidem for Sleep in Children With Autism
Stanford University
NCT05540574
Trial of Diphenhydramine for Sleep in Children With Autism
Stanford University
NCT05501678
Trial of Suvorexant for Sleep in Children With Autism
Stanford University
NCT05546554
A Study of Esomeprazole in Children With Autism
Stanford University
NCT03866668
Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism
Stanford University
NCT06627205
Biomarkers Research in Anxiety for Validation and Efficacy
Boston Children's Hospital
NCT06221176
TF-CBT for Autistic Youth Pilot Implementation - Open Pilot
Dartmouth-Hitchcock Medical Center
NCT07420478
Better Social, Emotional Communication, Healthy Relationship and ASD Accommodation Skills: Emotional Intelligence ("EQ") Training for Autistic People and ASD Accommodation Training for People Who Care
Kairon Connect, PBC
NCT07315867
Project VOICES: Vocal Optimization in Children Elevating the Spectrum
Vanderbilt University Medical Center
NCT06875843
FLIGHT - Autism: Education and Health Coaching Program Focused on Modifiable Lifestyle Factors for Parents
Documenting Hope Project
NCT07375537
The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol
University of Pittsburgh
NCT06386029
An Open Label Study of CM-AT for the Treatment of Children With Autism
Curemark
NCT02649959
Mitochondrial Dysfunction in Autism Spectrum Disorder
University of Arkansas
NCT02000284
Genetic Contributions to Autism Spectrum Disorders
Boston Children's Hospital
NCT01160783
Project AFECT (Autism Family Empowerment Coaching and Training Program)
Stanford University
NCT05910502
Developing Treatment, Treatment Validation and Treatment Scope in the Setting of an Autism Clinical Trial
Rutgers, The State University of New Jersey
NCT01260961
A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism
Stanford University
NCT03778827
Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism
Rutgers, The State University of New Jersey
NCT02677051
Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism
University of California, San Diego
NCT04517799
The Effectiveness of an Autistic-delivered Peer-support Intervention for Autistic Adults: Community Autism Peer Specialist (CAPS) Program
Drexel University
NCT05702658
Pilot Trial of Pregnenolone in Autism
Stanford University
NCT02627508
Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder
Children's Hospital Medical Center, Cincinnati
NCT06670040
Adapting BA for Minimally Verbal Autistic Adults
Rutgers, The State University of New Jersey
NCT06064422
Pediatric Open-Label Extension Study
Sumitomo Pharma America
NCT01914393
A Lead-in Study Evaluating Efficacy of GuessWhat Mobile App Therapy for Children With Autism
Stanford University
NCT04739982
Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine
Forest Laboratories
NCT01592747
Predictors of Caregiver Adaptation to Pervasive Developmental Disorders
National Human Genome Research Institute (NHGRI)
NCT00496210
Exome Sequencing in Autistic Spectrum Disorder
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT01059201
Autism Intervention Research Network for Behavioral Health (AIR-B II): Deployment Into Elementary Schools
Health Resources and Services Administration (HRSA)
NCT01724047
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
University of South Florida
NCT02028247
Adaptive Interventions for Minimally Verbal Children With ASD in the Community
University of California, Los Angeles
NCT01751698
A Trial of CM-AT in Children With Autism
Curemark
NCT00881452
Cord Blood Infusion for Children With Autism Spectrum Disorder
Joanne Kurtzberg, MD
NCT02847182
hCT-MSC in Children With Autism Spectrum Disorder
Joanne Kurtzberg, MD
NCT04089579
Intensive Intervention for Toddlers With Autism (EARLY STEPS)
University of California, Davis
NCT00698997
Randomized Controlled Trial of the P.L.A.Y. (Play and Language for Autistic Youngsters) Project Intervention for Autism
Richard Solomon MD
NCT01768806
Open-label Study of Safety and Tolerability of Memantine in Children With Autism
Forest Laboratories
NCT01999894
A Study of the Effectiveness and Safety of Two Doses of Risperidone in the Treatment of Children and Adolescents With Autistic Disorder
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
NCT00576732
Show Me to Help Me
Akron Children's Hospital
NCT01311596
Study of Toddlers With Language Delay
National Institute of Mental Health (NIMH)
NCT01339767
Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism
Emory University
NCT03152383
An Autism Study Using Nambudripad's Food Allergy Elimination Treatments
Nambudripad's Allergy Research Foundation
NCT00247156
A 12-Week Crossover Study to Assess the Efficacy, Safety and Tolerability of L1-79 in Subjects Aged 12-21 Years With Autism Spectrum Disorder
Yamo Pharmaceuticals
NCT05067582
Adapting an Advocacy Services Intervention for Latinx Families of Transition-aged Youth With Autism Spectrum Disorder
Vanderbilt University
NCT06207149
Randomized Study of Fluoxetine in Children and Adolescents With Autism
Icahn School of Medicine at Mount Sinai
NCT00004486
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
University of South Florida
NCT01178385
Services to Enhance Social Functioning in Adults With Autism Spectrum Disorders
University of Pennsylvania
NCT04788537
Sulforaphane-rich Broccoli Sprout Extract for Autism
Andrew Zimmerman
NCT01474993
Social Cognition and Interaction Training for Autism
University of North Carolina, Chapel Hill
NCT02382172
Risperidone Treatment In Children With Autism Spectrum Disorder And High Levels Of Repetitive Behavior
University of California, Los Angeles
NCT01171937
Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD
Massachusetts General Hospital
NCT04569058
Autologous Cord Blood Stem Cells for Autism
Sutter Health
NCT01638819
Divalproex Sodium vs. Placebo in Childhood/Adolescent Autism
Montefiore Medical Center
NCT00211757
Study of Paliperidone ER in Adolescents and Young Adults With Autism
Indiana University School of Medicine
NCT00549562
Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children
The University of Texas Health Science Center, Houston
NCT00178503
MENTIS Personal Health Record Rapid Pilot Research Deployment and Evaluation
Northeastern University
NCT02090491
In Vivo Imaging of Therapeutic Electric Current Flow
University of Florida
NCT02453763
Coaching Children With Anxiety and Autism Through Telehealth
Medical University of South Carolina
NCT05588570
A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms
University of Oklahoma
NCT00541346
Effect of Parenting With Positive Interven on Comm Inclusion for Military Connected and Dependents With Autism
Virginia Commonwealth University
NCT05580432
Testing a Novel Speech Intervention in Minimally Verbal Children With Autism Spectrum Disorder (ASD)
Beth Israel Deaconess Medical Center
NCT03015272
An Open-Label Trial of Aripiprazole in Autism Spectrum Disorders
Cambridge Health Alliance
NCT00308074
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 3 |
| Phase 2 | 23 |
| Phase 3 | 5 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Autism Trial Landscape
ClinicalTrials.gov lists 105 US studies indexed under Autism, and 49 of those are currently open to recruitment — roughly 47% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Autism shows 8 late-stage studies (Phase 3 and Phase 4 combined) alongside 26 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Autism is led by Stanford University with 16 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Autism?
PlainTrial tracks 105 US clinical trials for Autism, of which 49 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Autism?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.