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Low Back Pain: later-stage trial registry
31 of 123 indexed Low Back Pain trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #97 of 28,707 conditions by registered trial count.
123 US clinical trials · 31 currently recruiting · #97 of 28,707 conditions by registered trial count
Low Back Pain: 123 US clinical trials tracked, 31 recruiting.
Low Back Pain is the subject of 123 registered US clinical trials on ClinicalTrials.gov, 31 of them currently open to new participants. 20 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is University of Utah, running 8 of these trials.
Enrollment posture brief
Registry condition low-back-pain
OPEN 31 | RECR 25% | LATE 20 | EARLY 12 | RANK #97 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Overweight (25% recruiting · 198 trials)
Low Back Pain lists 31 open slots (25% of 123 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Low Back Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Low Back Pain is recruiting below its size-band peers.
31 of 123 indexed trials (25.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Low Back Pain trials is spread across many organizations.
University of Utah accounts for 8 of 123 trials (6.5%). 80 distinct sponsors appear on at least one study for this condition label.
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Typical Low Back Pain enrolment sits around 97 participants.
Median target enrolment is 97 among the 123 trials that report a genuine target (sentinel values excluded). 63 of those (51.2%) plan for fewer than 100 participants.
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Low Back Pain research is mostly interventional.
108 interventional and 15 observational studies make up this index (87.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
123 total, page 1 of 3
Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)
San Diego State University
NCT07290361
The Spine Phenome Project
Ohio State University
NCT05776771
Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain
SpineZone Medical Fitness
NCT04081896
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
University of Utah
NCT04923334
Overlapping Pain Trajectory Study
Children's Hospital Medical Center, Cincinnati
NCT05752396
Wearable Spine Health System for Military Readiness
Ohio State University
NCT05944354
Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)
Evon Medics
NCT06671132
Time to BBVNA Relief
Yale University
NCT07433634
Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain
Edward Via Virginia College of Osteopathic Medicine
NCT06818175
Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial
Madigan Army Medical Center
NCT04704297
Biomechanical Validation of the CATT
VA Office of Research and Development
NCT06013878
Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
University of Utah
NCT05607381
A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy
Northwestern University
NCT07224945
Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.
Montefiore Medical Center
NCT05721027
Blood Flow Restriction Training as a Targeted Intervention for Rowers With Back Pain.
Loma Linda University
NCT07130812
Conventional vs Bipolar SIJ RFA for Treatment of Sacroiliac Joint Pain
University of Utah
NCT05409443
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
R3 Stem Cell
NCT06361485
Perspectives on Spinal Manipulative Therapy for Low Back Pain
University of Florida
NCT06590116
Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
University of Alabama at Birmingham
NCT05556902
Dronabinol as an Adjunct for Reducing Pain
Christopher D. Verri
NCT06454669
Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control
Boston Scientific Corporation
NCT07190807
Erector Spinae Plane Block for Acute Back Pain in the Emergency Department
Rush University Medical Center
NCT06745453
Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain
University of Minnesota
NCT04164225
AuriculoTherapy NeuroImaging
Keith M Vogt
NCT06825390
Is Conditioned Pain Modulation Predictive of Clinical Improvement in Patients With Chronic Low Back Pain?
Brooke Army Medical Center
NCT06544525
Treatment for Sacroiliac Joint Pain Using Platelet-rich Plasma (PRP) Versus Steroid/Anesthetic
University of Utah
NCT05121961
Chronic Low Back Pain and Osteopathic Manipulation Treatment
Edward Hines Jr. VA Hospital
NCT07161661
Non-surgical Spinal Decompression Therapy and Outcomes
University of South Florida
NCT06525896
Effect of Lumbar Manipulation on Intervertebral Motion, Pain, and Disability
Ithaca College
NCT06294132
Endogenous Opioid Response to Injections
Middle Tennessee Research Institute
NCT06666621
Ischemic Preconditioning in Osteoarthritis and Back Pain
University of Illinois at Chicago
NCT07003113
Resolving the Burden of Low Back Pain in Military Service Members and Veterans: A Pragmatic Clinical Trial
Sara Gorczynski
NCT04494490
SMART Stepped Care Management for Low Back Pain in the Military Health System
Brooke Army Medical Center
NCT04172038
Self-Administered Acupressure for Veterans With Chronic Back Pain
VA Office of Research and Development
NCT05423145
Non-pharmacological Treatment for Pain After Spine Surgery
Dan Rhon
NCT04770480
The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain
SPR Therapeutics
NCT04246281
Development of STEPPT
San Diego State University
NCT06835439
Intracept Intraosseous Basivertebral Nerve Ablation
University of Utah
NCT05660512
LLLT to Reduce Low Back Pain
Mayo Clinic
NCT06007976
Two Point Discrimination
Children's Hospital Medical Center, Cincinnati
NCT03686748
Improving Core Strength in the Warfighter With a Novel Device
David Moss
NCT06797830
Health Coaching for Back Pain After Emergency Department Discharge
Vanderbilt University Medical Center
NCT06400602
TeleYoga for Chronic Low Back Pain: A Quantitative and Qualitative Study
Taylor Rees
NCT07216417
VIA Disc NP Pilot for Patients With Symptomatic Degenerated Discs
VIVEX Biologics
NCT05201287
VIA Disc Nucleus Pulposus Older Patients Pilot
VIVEX Biologics
NCT05412277
Analysis of Crepitus in Human Subjects
National University of Health Sciences
NCT05425017
Prevention of Low Back Pain in the Military
University of Florida
NCT00373009
Targeted Interventions to Prevent Chronic Low Back Pain in High Risk Patients
University of Pittsburgh
NCT02647658
Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain
Purdue Pharma
NCT01358526
Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Experienced Subjects
BioDelivery Sciences International
NCT01675167
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 5 |
| Phase 3 | 12 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Low Back Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Low Back Pain trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Low Back Pain page
123 registered trials, 31 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 31 Low Back Pain trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Utah sponsors the most Low Back Pain trials on record, review their full trial history before evaluating a specific study. See University of Utah's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Low Back Pain condition card totals 123 registered trials; most-linked intervention Placebo; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.