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NCT04246281 · ClinicalTrials.gov registry record · NA
The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain
A NA study of Low Back Pain and Back Pain, sponsored by SPR Therapeutics.
- Active
- Registry status
- NA
- Development phase
- 230
- Enrollment target
- 18
- Study locations
NCT04246281: Active NA study of Low Back Pain and Back Pain, sponsored by SPR Therapeutics.
NCT04246281 is a NA study of Low Back Pain and Back Pain that is active but no longer recruiting, run by SPR Therapeutics. The registered enrollment target is 230 participants, below the 502-participant average among 122 other Low Back Pain trials with a reported enrollment target (54% lower). The trial reports 18 study locations across 16 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04246281, a NA study of Low Back Pain and Back Pain, is active but no longer recruiting, sponsored by SPR Therapeutics.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 230 participants
- Enrollment target
- 18
- Study locations
Study Summary
The purpose of this study is to compare standard of care treatments for back pain to electrical stimulation. Stimulation is delivering small amounts of electricity to the nerves in your low back. This study will use a device called the SPRINT Peripheral Nerve Stimulation (PNS) System. The device is cleared by the FDA for up to 60 days of use for the relief of chronic or acute pain (including back pain)
Primary Outcome
Average pain is measured using question 5 from the Brief Pain Inventory- Short Form (BPI-5). BPI-5 is a scale of 0 to 10 where 0 represents no pain and 10 represents worst pain.
Conditions Studied
Interventions
- DEVICE SPRINT Peripheral Nerve Stimulation (PNS) System
- PROCEDURE Standard interventional management of low back pain
Study Locations (18)
North Carolina
- Duke University - Durham
- Center for Clinical Research - Winston-Salem
Virginia
- Virginia iSpine Physicians - Richmond
- Hunter Holmes McGuire Veterans Affairs Medical Center - Richmond
Arkansas
- University of Arkansas for Medical Sciences - Little Rock
California
- IPM Medical Group - Walnut Creek
Colorado
- Denver Back Pain Specialists - Greenwood Village
District of Columbia
- International Spine, Pain & Performance Center - Washington D.C.
Georgia
- Emory University - Atlanta
Idaho
- Northwest Speciality Hospital - Post Falls
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 230 participants |
| Start Date | 2020-06-17 |
| Est. Completion | 2027-04 |
| Phase | NA |
What the registry record for NCT04246281 still lists
NCT04246281 is an interventional study that assigns participants to a tested intervention. The registered 230 participants enrollment target is mid-sized for trials with a published cap, below the 502-participant average among 122 other Low Back Pain trials with a reported enrollment target (54% lower).
The record links to 2 conditions, with Low Back Pain appearing as the primary indexed condition, and to 2 interventions - of which SPRINT Peripheral Nerve Stimulation (PNS) System is the first listed.
NCT04246281 lists 18 locations in 16 states (North Carolina, Virginia, Arkansas).
Frequently Asked Questions
What is clinical trial NCT04246281 about?
NCT04246281 is a clinical study titled "The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain". The purpose of this study is to compare standard of care treatments for back pain to electrical stimulation. Stimulation is delivering small amounts of electricity to the nerves in your low back. This study will use a device called the SPRINT Peripheral Nerve Stimulation (PNS) System. The device is ...
What is the current status of trial NCT04246281?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 230 participants. The study started on 2020-06-17. Estimated completion is 2027-04.
What conditions does trial NCT04246281 study?
This clinical trial studies the following conditions: Low Back Pain, Back Pain.
What interventions are being tested in trial NCT04246281?
The interventions under investigation include: SPRINT Peripheral Nerve Stimulation (PNS) System (DEVICE), Standard interventional management of low back pain (PROCEDURE).
Who is sponsoring clinical trial NCT04246281?
This trial is sponsored by SPR Therapeutics, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04246281 being conducted?
This trial has 18 study locations across Arkansas, California, Colorado, District of Columbia, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Low Back Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04246281's enrollment target sits among peer trials
230 27th of 122 higher than 96 of 122 other Low Back Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Low Back Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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