Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06825390 · ClinicalTrials.gov registry record · NA
AuriculoTherapy NeuroImaging
A NA study of Low Back Pain and Chronic Low Back Pain, sponsored by Keith M Vogt.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06825390: Recruiting NA study of Low Back Pain and Chronic Low Back Pain, sponsored by Keith M Vogt.
NCT06825390 is a NA study of Low Back Pain and Chronic Low Back Pain that is actively recruiting participants, run by Keith M Vogt. The registered enrollment target is 60 participants, below the 503-participant average among 122 other Low Back Pain trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06825390, a NA study of Low Back Pain and Chronic Low Back Pain, is actively recruiting participants, sponsored by Keith M Vogt.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a clinical study of patients who have low back pain (for at least 6 months). The goal is to understand, with brain imaging, how auriculotherapy (an acupuncture-like stimulation of the ear) may work to relieve pain. There are 4 total study visits, divided into two pairs of visits that occur before and 5-7 days after receiving either a real or sham auriculotherapy treatment. The cryo-IQ device will be used, to stimulate 7 small areas on both ears with a focused jet of cold as a small amount of compressed gas is released. This is generally not painful, and less invasive, compared to using needles for auriculotherapy.
Primary Outcome
Calculated T-statistic for contrast of analyzed functional near-infrared spectroscopy (fNIRS) signal change, comparing responses from stimulation of the ipsilateral ear at the auricular points corresponding to the lumbar-spine vs. thumb. A T-statistic of 0 indicates no difference; more positive scores mean stronger fNIRS signal change with stimulation of the lumbar point, compared to stimulation of the thumb point; more negative scores mean change with stimulation of the thumb, compared to the l
Conditions Studied
Interventions
- DEVICE Cryo-auriculotherapy
- DEVICE Sham auriculotherapy
- OTHER Experimental auricular stimulation
Study Locations (1)
Pennsylvania
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-07-30 |
| Est. Completion | 2029-04-30 |
| Phase | NA |
What NCT06825390 shows while recruiting
NCT06825390 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 503-participant average among 122 other Low Back Pain trials with a reported enrollment target (88% lower).
The record links to 10 conditions, with Low Back Pain appearing as the primary indexed condition, and to 3 interventions - of which Cryo-auriculotherapy is the first listed.
NCT06825390 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06825390 about?
NCT06825390 is a clinical study titled "AuriculoTherapy NeuroImaging". This is a clinical study of patients who have low back pain (for at least 6 months). The goal is to understand, with brain imaging, how auriculotherapy (an acupuncture-like stimulation of the ear) may work to relieve pain. There are 4 total study visits, divided into two pairs of visits that occur b...
What is the current status of trial NCT06825390?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-07-30. Estimated completion is 2029-04-30.
What conditions does trial NCT06825390 study?
This clinical trial studies the following conditions: Low Back Pain, Chronic Low Back Pain, Back Pain, Low, Back Pain Lower Back Chronic, Lumbar Disc Disease.
What interventions are being tested in trial NCT06825390?
The interventions under investigation include: Cryo-auriculotherapy (DEVICE), Sham auriculotherapy (DEVICE), Experimental auricular stimulation (OTHER).
Who is sponsoring clinical trial NCT06825390?
This trial is sponsored by Keith M Vogt, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06825390 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Low Back Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06825390's enrollment target sits among peer trials
60 79th of 122 higher than 39 of 122 other Low Back Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Low Back Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Erector Spinae Plane Block for Acute Back Pain in the Emergency Department
RECRUITING · NA
-
A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy
RECRUITING · NA
-
Ischemic Preconditioning in Osteoarthritis and Back Pain
RECRUITING · NA
-
Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain
RECRUITING · NA
-
Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
RECRUITING · NA
-
Perspectives on Spinal Manipulative Therapy for Low Back Pain
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00576069 · 60 participants
Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
- NCT01297400 · 60 participants · Phase 2
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
- NCT01734122 · 60 participants
Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
- NCT01804634 · 60 participants · Phase 2
Reduced Intensity Haploidentical BMT for High Risk Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI