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Overlapping Pain Trajectory Study
NCT05752396 · View on ClinicalTrials.gov ↗
Study Summary
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. 2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition to COPCs in youth. Participation includes: * quantitative sensory testing * blood draw * sleep assessment * questionnaires
Conditions Studied
Interventions
- OTHER Conditioned Pain Modulation
- OTHER Offset Analgesia
- OTHER Spatial Summation
- OTHER Temporal Summation
Study Locations (1)
Ohio
- Cincinnati Children's Hospital — Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 420 participants |
| Start Date | 2023-03-01 |
| Est. Completion | 2028-07-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05752396
The ClinicalTrials.gov registry entry for NCT05752396 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 420 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 715 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 7 conditions, with Chronic Pain appearing as the primary indexed condition, and to 4 interventions — of which Conditioned Pain Modulation is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05752396 reports 1 study location spanning 1 distinct geographic area — top geographies include Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05752396 about?
NCT05752396 is a clinical study titled "Overlapping Pain Trajectory Study". The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COP...
What is the current status of trial NCT05752396?
This trial is currently recruiting. The enrollment target is 420 participants. The study started on 2023-03-01. Estimated completion is 2028-07-01.
What conditions does trial NCT05752396 study?
This clinical trial studies the following conditions: Chronic Pain, Healthy Volunteers, Low Back Pain, Migraine, Musculoskeletal Pain. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05752396?
The interventions under investigation include: Conditioned Pain Modulation (OTHER), Offset Analgesia (OTHER), Spatial Summation (OTHER), Temporal Summation (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05752396?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 715 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05752396 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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