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NCT05752396 · ClinicalTrials.gov registry record
Overlapping Pain Trajectory Study
A clinical trial of Chronic Pain and Healthy Volunteers, sponsored by Children's Hospital Medical Center, Cincinnati.
- Recruiting
- Registry status
- 420
- Enrollment target
- 1
- Study location
NCT05752396: Recruiting study of Chronic Pain and Healthy Volunteers, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT05752396 is a study of Chronic Pain and Healthy Volunteers that is actively recruiting participants, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 420 participants, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (46% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05752396, a study of Chronic Pain and Healthy Volunteers, is actively recruiting participants, sponsored by Children's Hospital Medical Center, Cincinnati.
- RECRUITING
- Registry status
- 420 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. 2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition to COPCs in youth. Participation includes: * quantitative sensory testing * blood draw * sleep assessment * questionnaires
Primary Outcome
-CPM is defined by the change in pressure thresholds (increase) before and during cold immersion. Pressure thresholds will be measured using an algometer.
Conditions Studied
Interventions
- OTHER Conditioned Pain Modulation
- OTHER Offset Analgesia
- OTHER Spatial Summation
- OTHER Temporal Summation
Study Locations (1)
Ohio
- Cincinnati Children's Hospital - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 420 participants |
| Start Date | 2023-03-01 |
| Est. Completion | 2028-07-01 |
What NCT05752396 shows while recruiting
NCT05752396 is an observational study that tracks outcomes without assigning an intervention. The registered 420 participants enrollment target is mid-sized for trials with a published cap, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (46% lower).
The record links to 7 conditions, with Chronic Pain appearing as the primary indexed condition, and to 4 interventions - of which Conditioned Pain Modulation is the first listed.
NCT05752396 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT05752396 about?
NCT05752396 is a clinical study titled "Overlapping Pain Trajectory Study". The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COP...
What is the current status of trial NCT05752396?
This trial is currently recruiting. The enrollment target is 420 participants. The study started on 2023-03-01. Estimated completion is 2028-07-01.
What conditions does trial NCT05752396 study?
This clinical trial studies the following conditions: Chronic Pain, Healthy Volunteers, Low Back Pain, Migraine, Musculoskeletal Pain.
What interventions are being tested in trial NCT05752396?
The interventions under investigation include: Conditioned Pain Modulation (OTHER), Offset Analgesia (OTHER), Spatial Summation (OTHER), Temporal Summation (OTHER).
Who is sponsoring clinical trial NCT05752396?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05752396 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05752396's enrollment target sits among peer trials
420 31st of 301 higher than 271 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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