Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06544525 · ClinicalTrials.gov registry record · NA
Is Conditioned Pain Modulation Predictive of Clinical Improvement in Patients With Chronic Low Back Pain?
A NA study of Low Back Pain, sponsored by Brooke Army Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 57
- Enrollment target
- 1
- Study location
NCT06544525 is a NA study of Low Back Pain that is actively recruiting participants, run by Brooke Army Medical Center. The registered enrollment target is 57 participants, below the 503-participant average among 122 other Low Back Pain trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06544525, a NA study of Low Back Pain, is actively recruiting participants, sponsored by Brooke Army Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 57 participants
- Enrollment target
- 1
- Study location
Study Summary
Conditioned pain modulation (CPM) a measure of the effectiveness of the descending pain pathway and therefore a measure of the body's ability to perform endogenous analgesia. In subjects with normal function of the descending pain pathway, the net-effect during CPM testing is anti-nociceptive, or inhibition of the ascending pain pathway. In those with impaired descending pain pathway function, the response to CPM testing is pro-nociceptive, indicating that the body is unable to inhibit the pain signal, or may even amplify it. There is literature that supports the presence of impaired CPM, and therefore impaired descending pain pathway function, in numerus chronic pain conditions, including low back pain. Impaired descending pain pathway function may be contributing to this chronic pain presentation. This study will give us information on whether a typical physical therapy plan of care is able to improve impaired CPM, and if CPM values are predictive of improvement in physical therapy.
Conditions Studied
Interventions
- OTHER Physical therapy
Study Locations (1)
Texas
- Brooke Army Medical Center - Fort Sam Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 57 participants |
| Start Date | 2024-09-19 |
| Est. Completion | 2025-07 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06544525
The ClinicalTrials.gov registry entry for NCT06544525 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 57 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 503-participant average among 122 other Low Back Pain trials with a reported enrollment target (89% lower). The listed sponsor is Brooke Army Medical Center, which has 54 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Low Back Pain appearing as the primary indexed condition, and to 1 intervention - of which Physical therapy is the first listed.
NCT06544525 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06544525 about?
NCT06544525 is a clinical study titled "Is Conditioned Pain Modulation Predictive of Clinical Improvement in Patients With Chronic Low Back Pain?". Conditioned pain modulation (CPM) a measure of the effectiveness of the descending pain pathway and therefore a measure of the body's ability to perform endogenous analgesia. In subjects with normal function of the descending pain pathway, the net-effect during CPM testing is anti-nociceptive, or in...
What is the current status of trial NCT06544525?
This trial is currently recruiting. It is a NA study. The enrollment target is 57 participants. The study started on 2024-09-19. Estimated completion is 2025-07.
What conditions does trial NCT06544525 study?
This clinical trial studies the following conditions: Low Back Pain.
What interventions are being tested in trial NCT06544525?
The interventions under investigation include: Physical therapy (OTHER).
Who is sponsoring clinical trial NCT06544525?
This trial is sponsored by Brooke Army Medical Center, which has 54 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06544525 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Low Back Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Erector Spinae Plane Block for Acute Back Pain in the Emergency Department
RECRUITING · NA
-
A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy
RECRUITING · NA
-
Ischemic Preconditioning in Osteoarthritis and Back Pain
RECRUITING · NA
-
Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain
RECRUITING · NA
-
Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
RECRUITING · NA
-
Perspectives on Spinal Manipulative Therapy for Low Back Pain
RECRUITING · NA
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.