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2026 data Public-data reference. official source

Kidney Transplantation

Open-data reference.

35 US clinical trials · 8 currently recruiting

Active & Recent Trials

RECRUITING NA 3,306 participants

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

University of British Columbia

NCT03674307

RECRUITING Phase 4 350 participants

Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.

Mayo Clinic

NCT06568549

RECRUITING NA 100 participants

Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision

Hennepin Healthcare Research Institute

NCT05879302

RECRUITING Phase 1 50 participants

Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD

United Therapeutics

NCT06878560

RECRUITING Phase 1 50 participants

Study to Evaluate the Safety and Efficacy of the GGTA1 KO Thymokidney in Patients With ESRD

United Therapeutics

NCT07224763

RECRUITING Phase 2 45 participants

Phase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation

Alexion Pharmaceuticals

NCT06744647

RECRUITING Phase 2 34 participants

REgulatory T Cell Therapy to Achieve Immunosuppression REduction

Singulera Therapeutics

NCT06552169

RECRUITING NA 15 participants

Prehabilitation for Kidney Transplant Candidates

The Methodist Hospital Research Institute

NCT06886256

ACTIVE NOT RECRUITING NA 206 participants

APOL1 Genetic Testing Program for Living Donors

Northwestern University

NCT04910867

ACTIVE NOT RECRUITING NA 70 participants

Watermelon/UBIQuinone Study

University of California, San Francis

NCT04972552

ACTIVE NOT RECRUITING Phase 2 30 participants

The Use of Hepatitis C Positive Kidneys in Hepatitis C Negative Kidney Transplant Recipients

Amit D Tevar, MD

NCT03809533

ACTIVE NOT RECRUITING Phase 4 28 participants

Envarsus XR® in Adolescent Renal Transplant Recipients

University of California, Los Angeles

NCT03266393

ACTIVE NOT RECRUITING Phase 2 18 participants

A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PERSPECTIVE)

ITB-Med

NCT04803058

COMPLETED Phase 3 850 participants

Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant

Astellas Pharma Europe

NCT02118896

COMPLETED Phase 4 720 participants

Study of Therapeutic Monitoring of Mycophenolate Mofetil (MMF/CellCept) After Kidney Transplantation

Hoffmann-La Roche

NCT00087581

COMPLETED Phase 4 501 participants

Safety/Efficacy of Induction Agents With Tacrolimus, MMF, and Rapid Steroid Withdrawal in Renal Transplant Recipients

Astellas Pharma

NCT00113269

COMPLETED NA 350 participants

Antibody and Delayed Cyclosporine Versus Initial Cyclosporine Alone in Patients Receiving Kidney Transplants

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00007787

COMPLETED Phase 2 338 participants

Study of a JAK3 Inhibitor for the Prevention of Acute Rejection in Kidney Transplant Patients

Pfizer

NCT00483756

COMPLETED Phase 2 323 participants

A Study to Assess the Safety and Efficacy of Alefacept in Kidney Transplant Recipients

Astellas Pharma

NCT00543569

COMPLETED 307 participants

Proteogenomic Biomarker Panels in a Serial Blood & Urine Monitoring Study of Kidney Transplant Recipients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT01289717

COMPLETED NA 224 participants

Does an Abdominal Wall Nerve Block During Surgery Help Reduce Pain From Kidney Transplantation?

The Cleveland Clinic

NCT05280197

COMPLETED NA 170 participants

Intervention to Improve Adherence in Teen Kidney Transplant

McGill University Health Centre/Research Institute of the McGill University Health Centre

NCT01356277

COMPLETED NA 116 participants

Vitamin D Replacement After Kidney Transplant

University of Nebraska

NCT00748618

COMPLETED Phase 3 100 participants

An Evaluation of IV Gamma Globulin As a Method to Improve Kidney Transplant Survival in Patients With End-Stage Renal Disease Who Are Highly Sensitized to Transplant Antigens

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000935

COMPLETED 100 participants

Survey of Adherence to Immunosuppression and Other Medications in Kidney Transplant Patients

State University of New York - Downstate Medical Center

NCT00433134

COMPLETED NA 88 participants

HLA-Identical Sibling Renal Transplant Tolerance

Northwestern University

NCT00619528

COMPLETED 83 participants

Collection of Follow-up Data From CP-690,550-treated Kidney Transplant Recipients

Pfizer

NCT01375127

COMPLETED Phase 4 80 participants

Calcineurin Inhibitor Avoidance With Thymoglobulin and Sirolimus in Kidney Transplantation

Vanderbilt University

NCT00305396

COMPLETED Phase 1 59 participants

CCFZ533X2201 - PoC Study in de Novo Renal Transplantation

Novartis Pharmaceuticals

NCT02217410

COMPLETED Phase 2 46 participants

Extension Study Of Stage 1 Subjects Of Study A3921009 For The Prevention Of Acute Rejection In Kidney Transplant Patient

Pfizer

NCT00263328

COMPLETED Phase 3 45 participants

Safety & Efficacy of Certican in Pediatric de Novo Renal Transplant Patients

Novartis Pharmaceuticals

NCT00098241

COMPLETED 24 participants

Analysis of Donor Biopsy Tissue Samples at the Time of Kidney Transplant

Weill Medical College of Cornell University

NCT01271465

COMPLETED Phase 1 10 participants

Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in Adults

University of Wisconsin, Madison

NCT00078559

COMPLETED Phase 1 8 participants

Tolerance by Engaging Antigen During Cellular Homeostasis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03504241

COMPLETED

Intraperative Assessment of Renal Perfusion Using Infrared Imaging

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00595179

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 7
Phase 3 3
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Kidney Transplantation Trial Landscape

ClinicalTrials.gov lists 35 US studies indexed under Kidney Transplantation, and 8 of those are currently open to recruitment — roughly 23% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Kidney Transplantation shows 8 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Kidney Transplantation is led by National Institute of Allergy and Infectious Diseases (NIAID) with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 35 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Kidney Transplantation?

PlainTrial tracks 35 US clinical trials for Kidney Transplantation, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Kidney Transplantation?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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