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NCT06568549 · ClinicalTrials.gov registry record · Phase 4
Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.
A Phase 4 study of Kidney Transplantation and Mycophenolate Mofetil, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 350
- Enrollment target
- 3
- Study locations
NCT06568549: Recruiting Phase 4 study of Kidney Transplantation and Mycophenolate Mofetil, sponsored by Mayo Clinic.
NCT06568549 is a Phase 4 study of Kidney Transplantation and Mycophenolate Mofetil that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 350 participants, above the 257-participant average among 33 other Kidney Transplantation trials with a reported enrollment target (36% higher). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06568549, a Phase 4 study of Kidney Transplantation and Mycophenolate Mofetil, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 350 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this research is to determine the safety and efficacy of withdrawing MMF (Mycophenolate Mofetil) in kidney transplant recipients who are 55 years or older at the time of receiving a kidney transplant. We are comparing them to patients who receive the standard of care Mycophenolate Mofetil.
Primary Outcome
Total number of subjects to experience acute rejection of the renal transplant
Conditions Studied
Interventions
- DRUG Mycophenolate Mofetil (MMF) Maintenance Group
- DRUG Mycophenolate Mofetil (MMF) Withdrawal Group
Study Locations (3)
Arizona
- Mayo Clinic - Phoenix
Florida
- Mayo Clinic - Jacksonville
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 350 participants |
| Start Date | 2025-06-13 |
| Est. Completion | 2031-03-31 |
| Phase | Phase 4 |
What NCT06568549 shows while recruiting
NCT06568549 is an interventional study that assigns participants to a tested intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, above the 257-participant average among 33 other Kidney Transplantation trials with a reported enrollment target (36% higher).
The record links to 2 conditions, with Kidney Transplantation appearing as the primary indexed condition, and to 2 interventions - of which Mycophenolate Mofetil (MMF) Maintenance Group is the first listed.
NCT06568549 reports a single indexed study location in Arizona, Florida, Minnesota.
Frequently Asked Questions
What is clinical trial NCT06568549 about?
NCT06568549 is a clinical study titled "Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.". The purpose of this research is to determine the safety and efficacy of withdrawing MMF (Mycophenolate Mofetil) in kidney transplant recipients who are 55 years or older at the time of receiving a kidney transplant. We are comparing them to patients who receive the standard of care Mycophenolate Mof...
What is the current status of trial NCT06568549?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 350 participants. The study started on 2025-06-13. Estimated completion is 2031-03-31.
What conditions does trial NCT06568549 study?
This clinical trial studies the following conditions: Kidney Transplantation, Mycophenolate Mofetil.
What interventions are being tested in trial NCT06568549?
The interventions under investigation include: Mycophenolate Mofetil (MMF) Maintenance Group (DRUG), Mycophenolate Mofetil (MMF) Withdrawal Group (DRUG).
Who is sponsoring clinical trial NCT06568549?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06568549 being conducted?
This trial has 3 study locations across Arizona, Florida, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Kidney Transplantation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06568549's enrollment target sits among peer trials
350 5th of 33 higher than 28 of 33 other Kidney Transplantation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Kidney Transplantation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Envarsus XR® in Adolescent Renal Transplant Recipients
ACTIVE NOT RECRUITING · Phase 4
-
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Study of Therapeutic Monitoring of Mycophenolate Mofetil (MMF/CellCept) After Kidney Transplantation
COMPLETED · Phase 4
-
Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision
RECRUITING · NA
-
Prehabilitation for Kidney Transplant Candidates
RECRUITING · NA
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