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NCT03809533 · ClinicalTrials.gov registry record · Phase 2
The Use of Hepatitis C Positive Kidneys in Hepatitis C Negative Kidney Transplant Recipients
A Phase 2 study of Hepatitis C and Kidney Transplantation, sponsored by Amit D Tevar, MD.
- Active
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT03809533: Active Phase 2 study of Hepatitis C and Kidney Transplantation, sponsored by Amit D Tevar, MD.
NCT03809533 is a Phase 2 study of Hepatitis C and Kidney Transplantation that is active but no longer recruiting, run by Amit D Tevar, MD. The registered enrollment target is 30 participants, below the 1,890-participant average among 106 other Hepatitis C trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03809533, a Phase 2 study of Hepatitis C and Kidney Transplantation, is active but no longer recruiting, sponsored by Amit D Tevar, MD.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This is an open-label, pilot trial to test the safety and efficacy of transplantation of kidneys from hepatitis C seropositive non-viremic (HCV Ab+/NAT-) and HCV seropositive viremic (HCV Ab+/NAT+) donors to HCV seronegative recipients on the kidney transplant waitlist. Treatment and prophylaxis will be administered using a transmission-triggered approach for the first scenario (HCV Ab+/NAT- donors, arm 1) and a prophylaxis approach for the later scenario (HCV Ab+/NAT+ donors, arm 2).
Primary Outcome
Rate of adverse events due to sofosbuvir/velpatasvir (Epclusa) in patients in each experimental group
Conditions Studied
Interventions
- DRUG sofosbuvir/velpatasvir
Study Locations (1)
Pennsylvania
- UPMC - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2019-05-29 |
| Est. Completion | 2026-04-01 |
| Phase | Phase 2 |
What the registry record for NCT03809533 still lists
NCT03809533 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,890-participant average among 106 other Hepatitis C trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Hepatitis C appearing as the primary indexed condition, and to 1 intervention - of which sofosbuvir/velpatasvir is the first listed.
NCT03809533 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03809533 about?
NCT03809533 is a clinical study titled "The Use of Hepatitis C Positive Kidneys in Hepatitis C Negative Kidney Transplant Recipients". This is an open-label, pilot trial to test the safety and efficacy of transplantation of kidneys from hepatitis C seropositive non-viremic (HCV Ab+/NAT-) and HCV seropositive viremic (HCV Ab+/NAT+) donors to HCV seronegative recipients on the kidney transplant waitlist. Treatment and prophylaxis wil...
What is the current status of trial NCT03809533?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2019-05-29. Estimated completion is 2026-04-01.
What conditions does trial NCT03809533 study?
This clinical trial studies the following conditions: Hepatitis C, Kidney Transplantation.
What interventions are being tested in trial NCT03809533?
The interventions under investigation include: sofosbuvir/velpatasvir (DRUG).
Who is sponsoring clinical trial NCT03809533?
This trial is sponsored by Amit D Tevar, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03809533 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hepatitis C
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03809533's enrollment target sits among peer trials
30 83rd of 106 higher than 21 of 106 other Hepatitis C trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hepatitis C trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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