Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cannabis Use Disorder
Open-data reference.
35 US clinical trials · 25 currently recruiting
Active & Recent Trials
Integrated Treatment for Enhancing Growth in Recovery During Adolescence
Massachusetts General Hospital
NCT06395467
The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV
University of Miami
NCT05453513
SV2 PET Imaging With [11C]APP311
Yale University
NCT03995121
Genetics of Cannabis Use Disorder and Cannabinoid Response in Humans
Yale University
NCT06058702
Cannabis-Tobacco Co-Use Treatment Study
Medical University of South Carolina
NCT06883162
A Study of Cannabidiol in Young Adult Cannabis Users
University of Colorado, Denver
NCT06569394
Study of Oral Fluid Testing Approach
Boston Children's Hospital
NCT06891235
Cannabis Reduction and Functional Outcomes
Medical University of South Carolina
NCT07218471
Longitudinal Outpatient Treatment for Cannabis Use Disorder
University of Colorado, Boulder
NCT06107062
SCORE Emerging Adult Cannabis Use & Stress
Medical University of South Carolina
NCT05885542
Stress and Pain in People Living With HIV
Yale University
NCT06784908
Cannabidiol and Cannabis Concentrate Users
University of Colorado, Denver
NCT06575751
Evaluation of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users
Florida State University
NCT06085222
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
Massachusetts General Hospital
NCT06878859
Neuroimaging of Adolescent Cannabis Use Treatment
Indiana University
NCT07340554
Mitigating PTSD-CUD After Sexual Assault
University of Nevada, Las Vegas
NCT05989841
Determining the Effect of Six Weeks of Cannabis Abstinence on Fronto- Striatal fMRI Markers in Adolescents With Cannabis Use Disorder (ABSCAN)
University of Minnesota
NCT06124846
A Brief Intervention for Cannabis Use
Medical University of South Carolina
NCT06395389
SV2A Density Cannabis Use Disorder
Yale University
NCT05472818
RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative
NYU Langone Health
NCT07184983
Cannabinoids and Biological Reactivity to Stress
Florida State University
NCT06430580
Effects of THC on Alcohol Consumption and Neural Correlates of Reward
University of Colorado, Denver
NCT06446479
Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder (Pilot Study)
Massachusetts General Hospital
NCT06584942
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
Trustees of Dartmouth College
NCT06920238
Psilocybin-assisted Treatment for Cannabis Use Disorder
Johns Hopkins University
NCT06660381
Breathwork-assisted Treatment for Cannabis Use Disorder
Elias Dakwar
NCT05219825
UH3 Varenicline for Cannabis Use Disorder
Medical University of South Carolina
NCT03980561
Adaptive Treatment for Adolescent Cannabis Use Disorders
UConn Health
NCT01656707
Bupropion for ADHD in Adolescents With Substance Use Disorder
University of Colorado, Denver
NCT00936299
A Preliminary Investigation of Pre-Frontal Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Cannabis Use Disorder
Stanford University
NCT03144232
Integrated CBT for Cannabis Dependence With Co-occurring Anxiety Disorders
Louisiana State University and A&M College
NCT01875796
A Teleheath tDCS Approach to Decrease Cannabis Use
NYU Langone Health
NCT05005013
Treatment of Cannabis Use Disorder Among Adults With Comorbid Attention-Deficit/Hyperactivity Disorder
New York State Psychiatric Institute
NCT02803229
Reducing Cannabis Overuse With Prazosin
VA Puget Sound Health Care System
NCT04721353
Progesterone for Cannabis Withdrawal
Medical University of South Carolina
NCT03430050
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 9 |
| Phase 2 | 8 |
| Phase 3 | 1 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cannabis Use Disorder Trial Landscape
ClinicalTrials.gov lists 35 US studies indexed under Cannabis Use Disorder, and 25 of those are currently open to recruitment — roughly 71% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Cannabis Use Disorder shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 17 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Cannabis Use Disorder is led by Medical University of South Carolina with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 35 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cannabis Use Disorder?
PlainTrial tracks 35 US clinical trials for Cannabis Use Disorder, of which 25 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cannabis Use Disorder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.