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NCT00619528 · ClinicalTrials.gov registry record · NA
HLA-Identical Sibling Renal Transplant Tolerance
A NA study of Kidney Transplantation and Immunosuppression, sponsored by Northwestern University.
- Completed
- Registry status
- NA
- Development phase
- 88
- Enrollment target
- 1
- Study location
NCT00619528: Completed NA study of Kidney Transplantation and Immunosuppression, sponsored by Northwestern University.
NCT00619528 is a NA study of Kidney Transplantation and Immunosuppression that has completed, run by Northwestern University. The registered enrollment target is 88 participants, below the 265-participant average among 33 other Kidney Transplantation trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00619528, a NA study of Kidney Transplantation and Immunosuppression, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 88 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to attempt to eliminate the necessity of immunosuppressive therapy for HLA-identical sibling Kidney Transplants, examine cellular chimerism of donor hematopoietic stem cell (DHSC) lineages for pairs to demonstrate immunologic unresponsiveness, and to investigate the safety and efficacy of the treatment regimen including withdrawal of immunosuppression after one year post-transplant for those recipients having received DHSC infusions.
Primary Outcome
The ability to withdraw immunosuppression as above 24 months post-transplant with follow-up to 10 years.
Conditions Studied
Interventions
- BIOLOGICAL Infusion of Donor Hematopoietic Stem Cells and Campath-1H
Study Locations (1)
Illinois
- Northwestern Memorial Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2008-01 |
| Est. Completion | 2023-09 |
| Phase | NA |
What the finished NCT00619528 record still lists
NCT00619528 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 88 participants, a relatively small participant target, below the 265-participant average among 33 other Kidney Transplantation trials with a reported enrollment target (67% lower).
The record links to 3 conditions, with Kidney Transplantation appearing as the primary indexed condition, and to 1 intervention - of which Infusion of Donor Hematopoietic Stem Cells and Campath-1H is the first listed.
NCT00619528 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT00619528 about?
NCT00619528 is a clinical study titled "HLA-Identical Sibling Renal Transplant Tolerance". The purpose of this study is to attempt to eliminate the necessity of immunosuppressive therapy for HLA-identical sibling Kidney Transplants, examine cellular chimerism of donor hematopoietic stem cell (DHSC) lineages for pairs to demonstrate immunologic unresponsiveness, and to investigate the safe...
What is the current status of trial NCT00619528?
This trial is currently completed. It is a NA study. The enrollment target is 88 participants. The study started on 2008-01. Estimated completion is 2023-09.
What conditions does trial NCT00619528 study?
This clinical trial studies the following conditions: Kidney Transplantation, Immunosuppression, Graft Rejection.
What interventions are being tested in trial NCT00619528?
The interventions under investigation include: Infusion of Donor Hematopoietic Stem Cells and Campath-1H (BIOLOGICAL).
Who is sponsoring clinical trial NCT00619528?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00619528 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Kidney Transplantation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00619528's enrollment target sits among peer trials
88 17th of 33 higher than 17 of 33 other Kidney Transplantation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Kidney Transplantation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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