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ClinicalTrials.gov 25 recruiting now official registry

Infertility clinical trials

25 of 75 indexed Infertility trials are currently recruiting.

75 US clinical trials · 25 currently recruiting

Infertility is the subject of 75 registered US clinical trials on ClinicalTrials.gov, 25 of them currently open to new participants. 12 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Reproductive Medicine Associates of New Jersey, running 6 of these trials.

The research picture

Infertility has 75 registered US clinical trials, 25 of them open to new participants right now, about 33% of the total.

25
recruiting participants now
33%
of trials open to enrollment
12
in Phase 3–4 (later-stage)
6
top sponsor: Reproductive Medicine Associates of New Jersey
Phase 13Phase 22Phase 36Phase 46

Active & Recent Trials

75 total, page 1 of 2

RECRUITING 500,000 participants

Apple Women's Health Study

Apple

NCT04196595

RECRUITING 10,000 participants

Discarded Materials Study

Reproductive Medicine Associates of New Jersey

NCT01219335

RECRUITING 10,000 participants

Follow-up With Preimplantation Genetic Testing Patients

Genomic Prediction

NCT04477863

RECRUITING NA 4,000 participants

Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes

Weill Medical College of Cornell University

NCT04255615

RECRUITING NA 2,000 participants

Sex Selection of Human Spermatozoa

Weill Medical College of Cornell University

NCT05500573

RECRUITING NA 1,200 participants

Gamete Treatment to Correct Fertilization Failure

Weill Medical College of Cornell University

NCT01944332

RECRUITING 1,000 participants

Non-Euploid Embryo Transfer (NEET) Registry

Inception Fertility Research Institute

NCT07036536

RECRUITING 850 participants

Inherited Reproductive Disorders

National Institute of Environmental Health Sciences (NIEHS)

NCT01500447

RECRUITING 500 participants

Embryo Health Study

Genomic Prediction

NCT04528498

RECRUITING Phase 4 350 participants

GnRH for Luteal Support in IVF/ICSI/FET Cycles

University Reproductive Associates

NCT02357654

RECRUITING Phase 3 309 participants

Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial

University of California, San Francisco

NCT03011684

RECRUITING Phase 3 297 participants

Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp

Yale University

NCT06375811

RECRUITING NA 252 participants

Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield

Reproductive Medicine Associates of New Jersey

NCT06214936

RECRUITING 250 participants

DNA Analysis of Discarded Media Drops From the Clinical IVF Cycles

Colorado Center for Reproductive Medicine

NCT03717441

RECRUITING NA 250 participants

A Prospective Study of a Mosaic Embryo Transfer

Colorado Center for Reproductive Medicine

NCT04472156

RECRUITING Early Phase 1 240 participants

The Hysterosalpingogram (HSG) Experience And Tubal Spasm (HEAT) Study

University of Oklahoma

NCT07226310

RECRUITING NA 200 participants

Testicular Tissue Cryopreservation in Children

Mayo Clinic

NCT02872532

RECRUITING NA 187 participants

A Randomized Clinical Trial Comparing Embryo Euploidy Rates Following Ultrashort Versus Standard Abstinence

UConn Health

NCT07062237

RECRUITING NA 180 participants

Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score

Generation Next Fertility

NCT07020546

RECRUITING 155 participants

SprmPik AI Sperm Selection Study SiD, an Assistant for Sperm Selection During Intracytoplasmic Sperm Injection in Medically Assisted Reproduction: Effect on Fertilization, Blastocyst Formation, Early Pregnancy Loss, and Consistent Practice. A Prospective Pilot Study.

Ovation Fertility

NCT06518928

RECRUITING 100 participants

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT05440617

RECRUITING NA 70 participants

Language Matters: Exploring the Impact of Language Concordance on Fertility Treatment Progression

Washington University School of Medicine

NCT06636838

RECRUITING NA 50 participants

In Vitro Maturation of Human Eggs

Colorado Center for Reproductive Medicine

NCT06633120

RECRUITING NA 40 participants

Implementing a Pilot Patient Navigator Program to Improve Access to Infertility Care for Underserved Patients

Boston Medical Center

NCT06481319

RECRUITING Phase 1 5 participants

Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome

University of Colorado, Denver

NCT06414096

ACTIVE NOT RECRUITING 3,700 participants

Developmental Epidemiological Study of Children Born Through Reproductive Technology

University of California, San Francisco

NCT03799107

ACTIVE NOT RECRUITING 2,000 participants

The Women's Health Study: From Adolescence to Adulthood

Boston Children's Hospital

NCT01738204

ACTIVE NOT RECRUITING NA 1,600 participants

To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That Develop to the Point That They Are Able to be Transferred) in IVF Cycles.

MotilityCount aps

NCT07369362

ACTIVE NOT RECRUITING 1,250 participants

Genetic Epidemiology of Ovarian Aging

University of California, San Francisco

NCT00501800

ACTIVE NOT RECRUITING Phase 3 680 participants

Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.

IBSA Institut Biochimique

NCT04549116

ACTIVE NOT RECRUITING 500 participants

ANXA5 M2 Haplotyping in IVF Patients and Embryos

Genomic Prediction

NCT04544462

ACTIVE NOT RECRUITING NA 440 participants

Evaluation of the Alife Hera System as an Adjunctive Tool for the Prioritization of Embryos Deemed Suitable for Transfer

Alife Health

NCT05483985

ACTIVE NOT RECRUITING Phase 4 190 participants

Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation

Rachel Mejia

NCT05206448

ACTIVE NOT RECRUITING NA 160 participants

Fast Track to Fertility

University of Pennsylvania

NCT07154888

ACTIVE NOT RECRUITING NA 150 participants

Microfluidics Versus Gradient Centrifugation Effect on Euploidy Rates

Lawrence Engmann

NCT04744025

ACTIVE NOT RECRUITING NA 140 participants

Group Preconception Care for Fertility Patients

University of Pennsylvania

NCT05924464

ACTIVE NOT RECRUITING NA 84 participants

Reprometabolic Syndrome Mediates Subfertility in Obesity

University of Colorado, Denver

NCT02653092

ACTIVE NOT RECRUITING NA 40 participants

Strategies for Pregnancy Achievement

Courtney D.Lynch, PhD MPH

NCT03085212

ACTIVE NOT RECRUITING NA 34 participants

Ovarian Reserve Testing in Female Young Adult Cancer Survivors

University of California, San Diego

NCT01421095

COMPLETED NA 3,568 participants

Frozen Embryo Donation Study

Boston IVF

NCT01883934

COMPLETED 2,586 participants

Multi-center Study to Validate niPGT-A

Igenomix

NCT03520933

COMPLETED 1,474 participants

Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes

National Institute of Environmental Health Sciences (NIEHS)

NCT00011713

COMPLETED 1,459 participants

Global Study of Women's Health

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00849173

COMPLETED Phase 3 1,297 participants

A Clinical Trial to Evaluate the Efficacy and Safety of DR-2011 for In Vitro Fertilization

Duramed Research

NCT00615251

COMPLETED 1,235 participants

Infertility Markers in Serum, Urine, and Follicular Fluid

University of Pennsylvania

NCT00194220

COMPLETED Phase 4 1,139 participants

Vaginal Compared to Intramuscular Progesterone for Frozen Embryo Transfer

Shady Grove Fertility Reproductive Science Center

NCT02254577

COMPLETED NA 621 participants

Hysteroscopic Assessment of Fallopian Tubal Patency

University of Mississippi Medical Center

NCT02005263

COMPLETED Phase 2 520 participants

Investigation of a Long-Acting Follicle Stimulating Hormone in Infertile Women Undergoing Assisted Reproductive Technology (ART)

Merck KGaA, Darmstadt, Germany

NCT00505752

COMPLETED NA 503 participants

Conventional Infertility Treatment vs. Fast Track to IVF

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00260091

COMPLETED 475 participants

Molecular Associations With Reproductive Failure

University of Pittsburgh

NCT00298116

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Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 6
Phase 4 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Infertility Trial Landscape

75 indexed Infertility studies · 25 recruiting (33%).

Phase mix: 12 late (III/IV) vs 5 early (I/II).

Top sponsor: Reproductive Medicine Associates of New Jersey (6 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Infertility?

PlainTrial tracks 75 US clinical trials for Infertility, of which 25 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Infertility?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.