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ClinicalTrials.gov 25 recruiting now later-stage tilt

Infertility: later-stage trial registry

25 of 75 indexed Infertility trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #178 of 28,707 conditions by registered trial count.

75 US clinical trials · 25 currently recruiting · #178 of 28,707 conditions by registered trial count

Infertility: 75 US clinical trials tracked, 25 recruiting.

Infertility is the subject of 75 registered US clinical trials on ClinicalTrials.gov, 25 of them currently open to new participants. 12 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Reproductive Medicine Associates of New Jersey, running 6 of these trials.

Enrollment posture brief

Registry condition infertility

OPEN 25 | RECR 33% | LATE 12 | EARLY 5 | RANK #178 | SPON 6

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Acute Kidney Injury44%Infertility (this)33%Age-related Macular Degenera26.7%Tobacco Use Disorder25.3%Pulmonary Disease, Chronic O9.3%
Open-enrollment share among volume-matched conditions near Infertility

Infertility lists 25 open slots (33% of 75 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Infertility on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Infertility is recruiting below its size-band peers.

    25 of 75 indexed trials (33.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Infertility trials is spread across many organizations.

    Reproductive Medicine Associates of New Jersey accounts for 6 of 75 trials (8%). 49 distinct sponsors appear on at least one study for this condition label.

  3. Typical Infertility enrolment sits around 250 participants.

    Median target enrolment is 250 among the 75 trials that report a genuine target (sentinel values excluded). 21 of those (28%) plan for fewer than 100 participants.

  4. Infertility splits between interventional and observational designs.

    52 interventional and 23 observational studies make up this index (69.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 22Phase 36Phase 46

Open and recent trials

75 total, page 1 of 2

RECRUITING 500,000 participants

Apple Women's Health Study

Apple

NCT04196595

RECRUITING 10,000 participants

Discarded Materials Study

Reproductive Medicine Associates of New Jersey

NCT01219335

RECRUITING 10,000 participants

Follow-up With Preimplantation Genetic Testing Patients

Genomic Prediction

NCT04477863

RECRUITING NA 4,000 participants

Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes

Weill Medical College of Cornell University

NCT04255615

RECRUITING NA 2,000 participants

Sex Selection of Human Spermatozoa

Weill Medical College of Cornell University

NCT05500573

RECRUITING NA 1,200 participants

Gamete Treatment to Correct Fertilization Failure

Weill Medical College of Cornell University

NCT01944332

RECRUITING 1,000 participants

Non-Euploid Embryo Transfer (NEET) Registry

Inception Fertility Research Institute

NCT07036536

RECRUITING 850 participants

Inherited Reproductive Disorders

National Institute of Environmental Health Sciences (NIEHS)

NCT01500447

RECRUITING 500 participants

Embryo Health Study

Genomic Prediction

NCT04528498

RECRUITING Phase 4 350 participants

GnRH for Luteal Support in IVF/ICSI/FET Cycles

University Reproductive Associates

NCT02357654

RECRUITING Phase 3 309 participants

Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial

University of California, San Francisco

NCT03011684

RECRUITING Phase 3 297 participants

Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp

Yale University

NCT06375811

RECRUITING NA 252 participants

Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield

Reproductive Medicine Associates of New Jersey

NCT06214936

RECRUITING 250 participants

DNA Analysis of Discarded Media Drops From the Clinical IVF Cycles

Colorado Center for Reproductive Medicine

NCT03717441

RECRUITING NA 250 participants

A Prospective Study of a Mosaic Embryo Transfer

Colorado Center for Reproductive Medicine

NCT04472156

RECRUITING Early Phase 1 240 participants

The Hysterosalpingogram (HSG) Experience And Tubal Spasm (HEAT) Study

University of Oklahoma

NCT07226310

RECRUITING NA 200 participants

Testicular Tissue Cryopreservation in Children

Mayo Clinic

NCT02872532

RECRUITING NA 187 participants

A Randomized Clinical Trial Comparing Embryo Euploidy Rates Following Ultrashort Versus Standard Abstinence

UConn Health

NCT07062237

RECRUITING NA 180 participants

Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score

Generation Next Fertility

NCT07020546

RECRUITING 155 participants

SprmPik AI Sperm Selection Study SiD, an Assistant for Sperm Selection During Intracytoplasmic Sperm Injection in Medically Assisted Reproduction: Effect on Fertilization, Blastocyst Formation, Early Pregnancy Loss, and Consistent Practice. A Prospective Pilot Study.

Ovation Fertility

NCT06518928

RECRUITING 100 participants

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT05440617

RECRUITING NA 70 participants

Language Matters: Exploring the Impact of Language Concordance on Fertility Treatment Progression

Washington University School of Medicine

NCT06636838

RECRUITING NA 50 participants

In Vitro Maturation of Human Eggs

Colorado Center for Reproductive Medicine

NCT06633120

RECRUITING NA 40 participants

Implementing a Pilot Patient Navigator Program to Improve Access to Infertility Care for Underserved Patients

Boston Medical Center

NCT06481319

RECRUITING Phase 1 5 participants

Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome

University of Colorado, Denver

NCT06414096

ACTIVE NOT RECRUITING 3,700 participants

Developmental Epidemiological Study of Children Born Through Reproductive Technology

University of California, San Francisco

NCT03799107

ACTIVE NOT RECRUITING 2,000 participants

The Women's Health Study: From Adolescence to Adulthood

Boston Children's Hospital

NCT01738204

ACTIVE NOT RECRUITING NA 1,600 participants

To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That Develop to the Point That They Are Able to be Transferred) in IVF Cycles.

MotilityCount aps

NCT07369362

ACTIVE NOT RECRUITING 1,250 participants

Genetic Epidemiology of Ovarian Aging

University of California, San Francisco

NCT00501800

ACTIVE NOT RECRUITING Phase 3 680 participants

Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.

IBSA Institut Biochimique

NCT04549116

ACTIVE NOT RECRUITING 500 participants

ANXA5 M2 Haplotyping in IVF Patients and Embryos

Genomic Prediction

NCT04544462

ACTIVE NOT RECRUITING NA 440 participants

Evaluation of the Alife Hera System as an Adjunctive Tool for the Prioritization of Embryos Deemed Suitable for Transfer

Alife Health

NCT05483985

ACTIVE NOT RECRUITING Phase 4 190 participants

Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation

Rachel Mejia

NCT05206448

ACTIVE NOT RECRUITING NA 160 participants

Fast Track to Fertility

University of Pennsylvania

NCT07154888

ACTIVE NOT RECRUITING NA 150 participants

Microfluidics Versus Gradient Centrifugation Effect on Euploidy Rates

Lawrence Engmann

NCT04744025

ACTIVE NOT RECRUITING NA 140 participants

Group Preconception Care for Fertility Patients

University of Pennsylvania

NCT05924464

ACTIVE NOT RECRUITING NA 84 participants

Reprometabolic Syndrome Mediates Subfertility in Obesity

University of Colorado, Denver

NCT02653092

ACTIVE NOT RECRUITING NA 40 participants

Strategies for Pregnancy Achievement

Courtney D.Lynch, PhD MPH

NCT03085212

ACTIVE NOT RECRUITING NA 34 participants

Ovarian Reserve Testing in Female Young Adult Cancer Survivors

University of California, San Diego

NCT01421095

COMPLETED NA 3,568 participants

Frozen Embryo Donation Study

Boston IVF

NCT01883934

COMPLETED 2,586 participants

Multi-center Study to Validate niPGT-A

Igenomix

NCT03520933

COMPLETED 1,474 participants

Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes

National Institute of Environmental Health Sciences (NIEHS)

NCT00011713

COMPLETED 1,459 participants

Global Study of Women's Health

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00849173

COMPLETED Phase 3 1,297 participants

A Clinical Trial to Evaluate the Efficacy and Safety of DR-2011 for In Vitro Fertilization

Duramed Research

NCT00615251

COMPLETED 1,235 participants

Infertility Markers in Serum, Urine, and Follicular Fluid

University of Pennsylvania

NCT00194220

COMPLETED Phase 4 1,139 participants

Vaginal Compared to Intramuscular Progesterone for Frozen Embryo Transfer

Shady Grove Fertility Reproductive Science Center

NCT02254577

COMPLETED NA 621 participants

Hysteroscopic Assessment of Fallopian Tubal Patency

University of Mississippi Medical Center

NCT02005263

COMPLETED Phase 2 520 participants

Investigation of a Long-Acting Follicle Stimulating Hormone in Infertile Women Undergoing Assisted Reproductive Technology (ART)

Merck KGaA, Darmstadt, Germany

NCT00505752

COMPLETED NA 503 participants

Conventional Infertility Treatment vs. Fast Track to IVF

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00260091

COMPLETED 475 participants

Molecular Associations With Reproductive Failure

University of Pittsburgh

NCT00298116

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Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 6
Phase 4 6

Named interventions

Most-linked intervention names on Infertility records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

GnRH Drug
2 trials
Acupuncture Procedure
2 trials
Letrozole Drug
2 trials
Recombinant human chorionic gonadotropin (r-hCG) Drug
1 trials
Follitropin alfa 150 international unit (IU) Drug
1 trials
AS900672-Enriched 150 mcg Drug
1 trials
AS900672-Enriched 100 mcg Drug
1 trials
AS900672-Enriched 50 microgram (mcg) Drug
1 trials

US sites by state

Facility locations filed on Infertility trials. A trial with sites in several states counts in each.

California 15 trials
New Jersey 12 trials
Maryland 10 trials
Massachusetts 9 trials
Colorado 9 trials
Texas 8 trials
Pennsylvania 7 trials
New York 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Infertility page

75 registered trials, 25 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Infertility condition card totals 75 registered trials; most-linked intervention GnRH; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.