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ClinicalTrials.gov 25 recruiting now official registry

Infertility clinical trials

Every US clinical trial registered for Infertility — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

75 US clinical trials · 25 currently recruiting

The research picture

Infertility has 75 registered US clinical trials, 25 of them open to new participants right now — about 33% of the total.

25
recruiting participants now
33%
of trials open to enrollment
12
in Phase 3–4 (later-stage)
6
top sponsor: Reproductive Medicine Associates of New Jersey

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 500,000 participants

Apple Women's Health Study

Apple

NCT04196595

RECRUITING 10,000 participants

Discarded Materials Study

Reproductive Medicine Associates of New Jersey

NCT01219335

RECRUITING 10,000 participants

Follow-up With Preimplantation Genetic Testing Patients

Genomic Prediction

NCT04477863

RECRUITING NA 4,000 participants

Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes

Weill Medical College of Cornell University

NCT04255615

RECRUITING NA 2,000 participants

Sex Selection of Human Spermatozoa

Weill Medical College of Cornell University

NCT05500573

RECRUITING NA 1,200 participants

Gamete Treatment to Correct Fertilization Failure

Weill Medical College of Cornell University

NCT01944332

RECRUITING 1,000 participants

Non-Euploid Embryo Transfer (NEET) Registry

Inception Fertility Research Institute

NCT07036536

RECRUITING 850 participants

Inherited Reproductive Disorders

National Institute of Environmental Health Sciences (NIEHS)

NCT01500447

RECRUITING 500 participants

Embryo Health Study

Genomic Prediction

NCT04528498

RECRUITING Phase 4 350 participants

GnRH for Luteal Support in IVF/ICSI/FET Cycles

University Reproductive Associates

NCT02357654

RECRUITING Phase 3 309 participants

Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial

University of California, San Francis

NCT03011684

RECRUITING Phase 3 297 participants

Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp

Yale University

NCT06375811

RECRUITING NA 252 participants

Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield

Reproductive Medicine Associates of New Jersey

NCT06214936

RECRUITING 250 participants

DNA Analysis of Discarded Media Drops From the Clinical IVF Cycles

Colorado Center for Reproductive Medicine

NCT03717441

RECRUITING NA 250 participants

A Prospective Study of a Mosaic Embryo Transfer

Colorado Center for Reproductive Medicine

NCT04472156

RECRUITING Early Phase 1 240 participants

The Hysterosalpingogram (HSG) Experience And Tubal Spasm (HEAT) Study

University of Oklahoma

NCT07226310

RECRUITING NA 200 participants

Testicular Tissue Cryopreservation in Children

Mayo Clinic

NCT02872532

RECRUITING NA 187 participants

A Randomized Clinical Trial Comparing Embryo Euploidy Rates Following Ultrashort Versus Standard Abstinence

UConn Health

NCT07062237

RECRUITING NA 180 participants

Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score

Generation Next Fertility

NCT07020546

RECRUITING 155 participants

SprmPik AI Sperm Selection Study SiD, an Assistant for Sperm Selection During Intracytoplasmic Sperm Injection in Medically Assisted Reproduction: Effect on Fertilization, Blastocyst Formation, Early Pregnancy Loss, and Consistent Practice. A Prospective Pilot Study.

Ovation Fertility

NCT06518928

RECRUITING 100 participants

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT05440617

RECRUITING NA 70 participants

Language Matters: Exploring the Impact of Language Concordance on Fertility Treatment Progression

Washington University School of Medicine

NCT06636838

RECRUITING NA 50 participants

In Vitro Maturation of Human Eggs

Colorado Center for Reproductive Medicine

NCT06633120

RECRUITING NA 40 participants

Implementing a Pilot Patient Navigator Program to Improve Access to Infertility Care for Underserved Patients

Boston Medical Center

NCT06481319

RECRUITING Phase 1 5 participants

Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome

University of Colorado, Denver

NCT06414096

ACTIVE NOT RECRUITING 3,700 participants

Developmental Epidemiological Study of Children Born Through Reproductive Technology

University of California, San Francis

NCT03799107

ACTIVE NOT RECRUITING 2,000 participants

The Women's Health Study: From Adolescence to Adulthood

Boston Children's Hospital

NCT01738204

ACTIVE NOT RECRUITING NA 1,600 participants

To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That Develop to the Point That They Are Able to be Transferred) in IVF Cycles.

MotilityCount aps

NCT07369362

ACTIVE NOT RECRUITING 1,250 participants

Genetic Epidemiology of Ovarian Aging

University of California, San Francis

NCT00501800

ACTIVE NOT RECRUITING Phase 3 680 participants

Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.

IBSA Institut Biochimique

NCT04549116

ACTIVE NOT RECRUITING 500 participants

ANXA5 M2 Haplotyping in IVF Patients and Embryos

Genomic Prediction

NCT04544462

ACTIVE NOT RECRUITING NA 440 participants

Evaluation of the Alife Hera System as an Adjunctive Tool for the Prioritization of Embryos Deemed Suitable for Transfer

Alife Health

NCT05483985

ACTIVE NOT RECRUITING Phase 4 190 participants

Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation

Rachel Mejia

NCT05206448

ACTIVE NOT RECRUITING NA 160 participants

Fast Track to Fertility

University of Pennsylvania

NCT07154888

ACTIVE NOT RECRUITING NA 150 participants

Microfluidics Versus Gradient Centrifugation Effect on Euploidy Rates

Lawrence Engmann

NCT04744025

ACTIVE NOT RECRUITING NA 140 participants

Group Preconception Care for Fertility Patients

University of Pennsylvania

NCT05924464

ACTIVE NOT RECRUITING NA 84 participants

Reprometabolic Syndrome Mediates Subfertility in Obesity

University of Colorado, Denver

NCT02653092

ACTIVE NOT RECRUITING NA 40 participants

Strategies for Pregnancy Achievement

Courtney D.Lynch, PhD MPH

NCT03085212

ACTIVE NOT RECRUITING NA 34 participants

Ovarian Reserve Testing in Female Young Adult Cancer Survivors

University of California, San Diego

NCT01421095

COMPLETED NA 3,568 participants

Frozen Embryo Donation Study

Boston IVF

NCT01883934

COMPLETED 2,586 participants

Multi-center Study to Validate niPGT-A

Igenomix

NCT03520933

COMPLETED 1,474 participants

Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes

National Institute of Environmental Health Sciences (NIEHS)

NCT00011713

COMPLETED 1,459 participants

Global Study of Women's Health

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00849173

COMPLETED Phase 3 1,297 participants

A Clinical Trial to Evaluate the Efficacy and Safety of DR-2011 for In Vitro Fertilization

Duramed Research

NCT00615251

COMPLETED 1,235 participants

Infertility Markers in Serum, Urine, and Follicular Fluid

University of Pennsylvania

NCT00194220

COMPLETED Phase 4 1,139 participants

Vaginal Compared to Intramuscular Progesterone for Frozen Embryo Transfer

Shady Grove Fertility Reproductive Science Center

NCT02254577

COMPLETED NA 621 participants

Hysteroscopic Assessment of Fallopian Tubal Patency

University of Mississippi Medical Center

NCT02005263

COMPLETED Phase 2 520 participants

Investigation of a Long-Acting Follicle Stimulating Hormone in Infertile Women Undergoing Assisted Reproductive Technology (ART)

Merck KGaA, Darmstadt, Germany

NCT00505752

COMPLETED NA 503 participants

Conventional Infertility Treatment vs. Fast Track to IVF

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00260091

COMPLETED 475 participants

Molecular Associations With Reproductive Failure

University of Pittsburgh

NCT00298116

COMPLETED Phase 3 405 participants

Comparison of MENOPUR Liquid and Powder in Women Undergoing Assisted Reproductive Technology (ART)

Ferring Pharmaceuticals

NCT04163458

COMPLETED NA 393 participants

Sperm Selection by Microfluidic Separation Improves Embryo Quality

University of California, San Francis

NCT03085433

COMPLETED 335 participants

Salivary Diagnostic Testing for IVF

Boston IVF

NCT02040545

COMPLETED NA 309 participants

Next Generation Sequencing Screening for Embryonic Ploidy Status

Reproductive Medicine Associates of New Jersey

NCT02032264

COMPLETED NA 264 participants

Communication With in Vitro Fertilization (IVF) Patients About Risks

University of Kansas Medical Center

NCT00722618

COMPLETED Phase 4 232 participants

Concomitant Administration of FSH With HCG Improves Oocyte Maturation and Quality Double -Blinded Randomized Trial

University of California, San Francis

NCT00854373

COMPLETED NA 164 participants

Evaluation of Patient Experience and Quality of Life During In Vitro Fertilization Treatment

University of Michigan

NCT03383848

COMPLETED NA 140 participants

Comparison of Transfers of Thawed Blastocysts Versus Blastocysts Derived From Thawed Bipronuclear Oocytes

Bruce Shapiro M.D.

NCT01247987

COMPLETED NA 130 participants

GnRH Antagonist to Prepare Recipients for Embryo Transfer

Institute for Human Reproduction (IHR)

NCT00460642

COMPLETED Phase 4 122 participants

Menopur Mixed Protocol

Ferring Pharmaceuticals

NCT01417195

COMPLETED Phase 2 120 participants

Benefits of Walnuts for Male Reproductive Health

University of California, Los Angeles

NCT01505140

COMPLETED 81 participants

KIDScore D3 Clinical Study

Vitrolife

NCT03740828

COMPLETED NA 80 participants

Effectiveness of Web-based Teaching to Traditional Patient Education in the Use of Injectable Fertility Medications

Wake Forest University Health Sciences

NCT02420964

COMPLETED NA 79 participants

Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss

Cornell University

NCT01785719

COMPLETED NA 71 participants

Online Mind/Body Program for Fertility

University of Vermont

NCT03343405

COMPLETED NA 60 participants

Evaluation of the Impact of Reduced Oxygen Concentration on Embryonic Development

Reproductive Medicine Associates of New Jersey

NCT02919384

COMPLETED Phase 1 60 participants

The Effect of Acupuncture on Infertility With In-Vitro Fertilization (IVF) Patients

National Center for Complementary and Integrative Health (NCCIH)

NCT00317317

COMPLETED NA 60 participants

Effect of Acupuncture on Vascular Biomarkers and Psychological Well-Being of Women Undergoing IVF

Texas Tech University Health Sciences Center

NCT02591186

COMPLETED Phase 3 40 participants

Vaginal Culture Using INVOcell Compared to Traditional IVF Incubation

Invaron Pharmaceuticals

NCT02363426

COMPLETED Phase 4 37 participants

Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF

Colorado Center for Reproductive Medicine

NCT00621179

COMPLETED 31 participants

Eeva™ Continued Access Study: Assessing the Usability of Eeva in a Clinical Setting

Progyny

NCT01617993

COMPLETED NA 30 participants

Estrogen Sensitivity and Ovulatory Dysfunction in Obesity

University of Colorado, Denver

NCT01381016

COMPLETED NA 27 participants

Oocyte Survival After Vitrification With Slush Nitrogen Compared With Liquid Nitrogen

Reproductive Medicine Associates of New Jersey

NCT04342364

COMPLETED 17 participants

Oocyte Cryopreservation Comparing Fresh and Vitrified Sibling Oocytes

UConn Health

NCT00986687

COMPLETED 6 participants

Embryo DNA Repair Capacity Project

Reproductive Medicine Associates of New Jersey

NCT03953859

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 6
Phase 4 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Infertility Trial Landscape

ClinicalTrials.gov lists 75 US studies indexed under Infertility, and 25 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Infertility shows 12 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Infertility is led by Reproductive Medicine Associates of New Jersey with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 75 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Infertility?

PlainTrial tracks 75 US clinical trials for Infertility, of which 25 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Infertility?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →