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Infertility clinical trials
Every US clinical trial registered for Infertility — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
75 US clinical trials · 25 currently recruiting
The research picture
Infertility has 75 registered US clinical trials, 25 of them open to new participants right now — about 33% of the total.
- 25
- recruiting participants now
- 33%
- of trials open to enrollment
- 12
- in Phase 3–4 (later-stage)
- 6
- top sponsor: Reproductive Medicine Associates of New Jersey
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Apple Women's Health Study
Apple
NCT04196595
Discarded Materials Study
Reproductive Medicine Associates of New Jersey
NCT01219335
Follow-up With Preimplantation Genetic Testing Patients
Genomic Prediction
NCT04477863
Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes
Weill Medical College of Cornell University
NCT04255615
Sex Selection of Human Spermatozoa
Weill Medical College of Cornell University
NCT05500573
Gamete Treatment to Correct Fertilization Failure
Weill Medical College of Cornell University
NCT01944332
Non-Euploid Embryo Transfer (NEET) Registry
Inception Fertility Research Institute
NCT07036536
Inherited Reproductive Disorders
National Institute of Environmental Health Sciences (NIEHS)
NCT01500447
Embryo Health Study
Genomic Prediction
NCT04528498
GnRH for Luteal Support in IVF/ICSI/FET Cycles
University Reproductive Associates
NCT02357654
Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial
University of California, San Francis
NCT03011684
Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp
Yale University
NCT06375811
Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield
Reproductive Medicine Associates of New Jersey
NCT06214936
DNA Analysis of Discarded Media Drops From the Clinical IVF Cycles
Colorado Center for Reproductive Medicine
NCT03717441
A Prospective Study of a Mosaic Embryo Transfer
Colorado Center for Reproductive Medicine
NCT04472156
The Hysterosalpingogram (HSG) Experience And Tubal Spasm (HEAT) Study
University of Oklahoma
NCT07226310
Testicular Tissue Cryopreservation in Children
Mayo Clinic
NCT02872532
A Randomized Clinical Trial Comparing Embryo Euploidy Rates Following Ultrashort Versus Standard Abstinence
UConn Health
NCT07062237
Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score
Generation Next Fertility
NCT07020546
SprmPik AI Sperm Selection Study SiD, an Assistant for Sperm Selection During Intracytoplasmic Sperm Injection in Medically Assisted Reproduction: Effect on Fertilization, Blastocyst Formation, Early Pregnancy Loss, and Consistent Practice. A Prospective Pilot Study.
Ovation Fertility
NCT06518928
Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT05440617
Language Matters: Exploring the Impact of Language Concordance on Fertility Treatment Progression
Washington University School of Medicine
NCT06636838
In Vitro Maturation of Human Eggs
Colorado Center for Reproductive Medicine
NCT06633120
Implementing a Pilot Patient Navigator Program to Improve Access to Infertility Care for Underserved Patients
Boston Medical Center
NCT06481319
Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome
University of Colorado, Denver
NCT06414096
Developmental Epidemiological Study of Children Born Through Reproductive Technology
University of California, San Francis
NCT03799107
The Women's Health Study: From Adolescence to Adulthood
Boston Children's Hospital
NCT01738204
To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That Develop to the Point That They Are Able to be Transferred) in IVF Cycles.
MotilityCount aps
NCT07369362
Genetic Epidemiology of Ovarian Aging
University of California, San Francis
NCT00501800
Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.
IBSA Institut Biochimique
NCT04549116
ANXA5 M2 Haplotyping in IVF Patients and Embryos
Genomic Prediction
NCT04544462
Evaluation of the Alife Hera System as an Adjunctive Tool for the Prioritization of Embryos Deemed Suitable for Transfer
Alife Health
NCT05483985
Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation
Rachel Mejia
NCT05206448
Fast Track to Fertility
University of Pennsylvania
NCT07154888
Microfluidics Versus Gradient Centrifugation Effect on Euploidy Rates
Lawrence Engmann
NCT04744025
Group Preconception Care for Fertility Patients
University of Pennsylvania
NCT05924464
Reprometabolic Syndrome Mediates Subfertility in Obesity
University of Colorado, Denver
NCT02653092
Strategies for Pregnancy Achievement
Courtney D.Lynch, PhD MPH
NCT03085212
Ovarian Reserve Testing in Female Young Adult Cancer Survivors
University of California, San Diego
NCT01421095
Frozen Embryo Donation Study
Boston IVF
NCT01883934
Multi-center Study to Validate niPGT-A
Igenomix
NCT03520933
Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes
National Institute of Environmental Health Sciences (NIEHS)
NCT00011713
Global Study of Women's Health
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00849173
A Clinical Trial to Evaluate the Efficacy and Safety of DR-2011 for In Vitro Fertilization
Duramed Research
NCT00615251
Infertility Markers in Serum, Urine, and Follicular Fluid
University of Pennsylvania
NCT00194220
Vaginal Compared to Intramuscular Progesterone for Frozen Embryo Transfer
Shady Grove Fertility Reproductive Science Center
NCT02254577
Hysteroscopic Assessment of Fallopian Tubal Patency
University of Mississippi Medical Center
NCT02005263
Investigation of a Long-Acting Follicle Stimulating Hormone in Infertile Women Undergoing Assisted Reproductive Technology (ART)
Merck KGaA, Darmstadt, Germany
NCT00505752
Conventional Infertility Treatment vs. Fast Track to IVF
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00260091
Molecular Associations With Reproductive Failure
University of Pittsburgh
NCT00298116
Comparison of MENOPUR Liquid and Powder in Women Undergoing Assisted Reproductive Technology (ART)
Ferring Pharmaceuticals
NCT04163458
Sperm Selection by Microfluidic Separation Improves Embryo Quality
University of California, San Francis
NCT03085433
Salivary Diagnostic Testing for IVF
Boston IVF
NCT02040545
Next Generation Sequencing Screening for Embryonic Ploidy Status
Reproductive Medicine Associates of New Jersey
NCT02032264
Communication With in Vitro Fertilization (IVF) Patients About Risks
University of Kansas Medical Center
NCT00722618
Concomitant Administration of FSH With HCG Improves Oocyte Maturation and Quality Double -Blinded Randomized Trial
University of California, San Francis
NCT00854373
Evaluation of Patient Experience and Quality of Life During In Vitro Fertilization Treatment
University of Michigan
NCT03383848
Comparison of Transfers of Thawed Blastocysts Versus Blastocysts Derived From Thawed Bipronuclear Oocytes
Bruce Shapiro M.D.
NCT01247987
GnRH Antagonist to Prepare Recipients for Embryo Transfer
Institute for Human Reproduction (IHR)
NCT00460642
Menopur Mixed Protocol
Ferring Pharmaceuticals
NCT01417195
Benefits of Walnuts for Male Reproductive Health
University of California, Los Angeles
NCT01505140
KIDScore D3 Clinical Study
Vitrolife
NCT03740828
Effectiveness of Web-based Teaching to Traditional Patient Education in the Use of Injectable Fertility Medications
Wake Forest University Health Sciences
NCT02420964
Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss
Cornell University
NCT01785719
Online Mind/Body Program for Fertility
University of Vermont
NCT03343405
Evaluation of the Impact of Reduced Oxygen Concentration on Embryonic Development
Reproductive Medicine Associates of New Jersey
NCT02919384
The Effect of Acupuncture on Infertility With In-Vitro Fertilization (IVF) Patients
National Center for Complementary and Integrative Health (NCCIH)
NCT00317317
Effect of Acupuncture on Vascular Biomarkers and Psychological Well-Being of Women Undergoing IVF
Texas Tech University Health Sciences Center
NCT02591186
Vaginal Culture Using INVOcell Compared to Traditional IVF Incubation
Invaron Pharmaceuticals
NCT02363426
Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF
Colorado Center for Reproductive Medicine
NCT00621179
Eeva™ Continued Access Study: Assessing the Usability of Eeva in a Clinical Setting
Progyny
NCT01617993
Estrogen Sensitivity and Ovulatory Dysfunction in Obesity
University of Colorado, Denver
NCT01381016
Oocyte Survival After Vitrification With Slush Nitrogen Compared With Liquid Nitrogen
Reproductive Medicine Associates of New Jersey
NCT04342364
Oocyte Cryopreservation Comparing Fresh and Vitrified Sibling Oocytes
UConn Health
NCT00986687
Embryo DNA Repair Capacity Project
Reproductive Medicine Associates of New Jersey
NCT03953859
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 2 |
| Phase 3 | 6 |
| Phase 4 | 6 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Infertility Trial Landscape
ClinicalTrials.gov lists 75 US studies indexed under Infertility, and 25 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Infertility shows 12 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Infertility is led by Reproductive Medicine Associates of New Jersey with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 75 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Infertility?
PlainTrial tracks 75 US clinical trials for Infertility, of which 25 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Infertility?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.