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NCT02357654 · ClinicalTrials.gov registry record · Phase 4

GnRH for Luteal Support in IVF/ICSI/FET Cycles

A Phase 4 study of Infertility, sponsored by University Reproductive Associates.

Recruiting
Registry status
Phase 4
Development phase
350
Enrollment target
1
Study location

NCT02357654: Recruiting Phase 4 study of Infertility, sponsored by University Reproductive Associates.

NCT02357654 is a Phase 4 study of Infertility that is actively recruiting participants, run by University Reproductive Associates. The registered enrollment target is 350 participants, below the 7,585-participant average among 74 other Infertility trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02357654, a Phase 4 study of Infertility, is actively recruiting participants, sponsored by University Reproductive Associates.

RECRUITING
Registry status
Phase 4
Development phase
350 participants
Enrollment target
1
Study location

Study Summary

During IVF cycles an embryo is generally placed into the uterine cavity between 3 and 5 days after fertilization. For a successful pregnancy to take place, that embryo must then implant in the properly primed and staged endometrium, which subsequently must continue to develop to accommodate the growing and maturing embryo and then fetus. This process is normally regulated by hormonal interactions between the fetal, endometrial and luteal tissue. It has been found that after IVF additional support for the endometrium with progesterone improves implantation and subsequent live birth rates in IVF cycle . Recent data has shown that additional supplementation with a single administration of a GnRH agonist around the time the time of embryo transfer may further enhance these rates .

Conditions Studied

Interventions

  • DRUG placebo
  • DRUG GnRH

Study Locations (1)

New Jersey

  • University Reproductive Associates - Hasbrouck Heights

Trial Details

FieldValue
Enrollment Target 350 participants
Start Date 2015-11
Est. Completion 2026-07
Phase Phase 4

What NCT02357654 shows while recruiting

NCT02357654 is an interventional study that assigns participants to a tested intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, below the 7,585-participant average among 74 other Infertility trials with a reported enrollment target (95% lower).

The record links to 1 condition, with Infertility appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.

NCT02357654 reports a single indexed study location in New Jersey.

Frequently Asked Questions

What is clinical trial NCT02357654 about?

NCT02357654 is a clinical study titled "GnRH for Luteal Support in IVF/ICSI/FET Cycles". During IVF cycles an embryo is generally placed into the uterine cavity between 3 and 5 days after fertilization. For a successful pregnancy to take place, that embryo must then implant in the properly primed and staged endometrium, which subsequently must continue to develop to accommodate the grow...

What is the current status of trial NCT02357654?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 350 participants. The study started on 2015-11. Estimated completion is 2026-07.

What conditions does trial NCT02357654 study?

This clinical trial studies the following conditions: Infertility.

What interventions are being tested in trial NCT02357654?

The interventions under investigation include: placebo (DRUG), GnRH (DRUG).

Who is sponsoring clinical trial NCT02357654?

This trial is sponsored by University Reproductive Associates, which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02357654 being conducted?

This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Infertility

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02357654's enrollment target sits among peer trials

350 30th of 74 higher than 45 of 74 other Infertility trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Infertility trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02357654, the US trial registry maintained by the National Library of Medicine. NCT02357654 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.