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NCT02653092 · ClinicalTrials.gov registry record · NA
Reprometabolic Syndrome Mediates Subfertility in Obesity
A NA study of Obesity and Infertility, sponsored by University of Colorado, Denver.
- Active
- Registry status
- NA
- Development phase
- 84
- Enrollment target
- 1
- Study location
NCT02653092: Active NA study of Obesity and Infertility, sponsored by University of Colorado, Denver.
NCT02653092 is a NA study of Obesity and Infertility that is active but no longer recruiting, run by University of Colorado, Denver. The registered enrollment target is 84 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02653092, a NA study of Obesity and Infertility, is active but no longer recruiting, sponsored by University of Colorado, Denver.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 84 participants
- Enrollment target
- 1
- Study location
Study Summary
Obesity plays an adverse role at every stage of conception and pregnancy and mounting evidence implicates relative hypogonadotropic hypogonadism, and reduced menstrual cycle hormone secretion as likely contributors to the subfertility phenotype and possible contributors to complications of pregnancy and the developmental origin of adult diseases such as diabetes and cardiovascular disease. This study will be the first comprehensive investigation to tie together the patterns of hyperinsulinemia, hyperlipidemia and inflammation, characteristic of obesity and obesity-caused relative hypogonadotropic hypogonadotropism and its potential adverse reproductive outcomes. The investigators findings will be used to inform a subsequent clinical intervention to optimize reproductive outcomes for obese women and their offspring.
Primary Outcome
LH-Luteinizing Hormone Pulse Amplitude before and after administration of FFAs. This is a measure of the post supplementation frequent blood sampling session and the baseline session.
Conditions Studied
Interventions
- DRUG Insulin
- DRUG Heparin
- DRUG Intralipid
- DRUG GnRH
- DRUG Dextrose
Study Locations (1)
Colorado
- University of Colorado Denver - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2016-06 |
| Est. Completion | 2026-12-11 |
| Phase | NA |
What the registry record for NCT02653092 still lists
NCT02653092 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower).
The record links to 4 conditions, with Obesity appearing as the primary indexed condition, and to 5 interventions - of which Insulin is the first listed.
NCT02653092 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT02653092 about?
NCT02653092 is a clinical study titled "Reprometabolic Syndrome Mediates Subfertility in Obesity". Obesity plays an adverse role at every stage of conception and pregnancy and mounting evidence implicates relative hypogonadotropic hypogonadism, and reduced menstrual cycle hormone secretion as likely contributors to the subfertility phenotype and possible contributors to complications of pregnancy...
What is the current status of trial NCT02653092?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 84 participants. The study started on 2016-06. Estimated completion is 2026-12-11.
What conditions does trial NCT02653092 study?
This clinical trial studies the following conditions: Obesity, Infertility, Hyperinsulinemia, Hypogonadotropic Hypogonadotropism.
What interventions are being tested in trial NCT02653092?
The interventions under investigation include: Insulin (DRUG), Heparin (DRUG), Intralipid (DRUG), GnRH (DRUG), Dextrose (DRUG).
Who is sponsoring clinical trial NCT02653092?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02653092 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02653092's enrollment target sits among peer trials
84 534th of 1053 higher than 516 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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