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NCT00011713 · ClinicalTrials.gov registry record

Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes

A clinical trial of Infertility, sponsored by National Institute of Environmental Health Sciences (NIEHS).

Completed
Registry status
1,474
Enrollment target
1
Study location

NCT00011713: Completed study of Infertility, sponsored by National Institute of Environmental Health Sciences (NIEHS).

NCT00011713 is a study of Infertility that has completed, run by National Institute of Environmental Health Sciences (NIEHS). The registered enrollment target is 1,474 participants, below the 7,570-participant average among 74 other Infertility trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00011713, a study of Infertility, has completed, sponsored by National Institute of Environmental Health Sciences (NIEHS).

COMPLETED
Registry status
1,474 participants
Enrollment target
1
Study location

Study Summary

The purpose of the study is to investigate the relationship between environmental agents and reproductive health. Environmental agents of interest include exposure to chemicals such as polychlorinated biphenyls (PCBs), flame retardants, dioxins, bisphenol A, phthalates, pesticides, and metals like lead and cadmium. We are also interested in the relationship between reproductive health and lifestyle risk factors, such as exposure to environmental tobacco smoke. Enrollees are asked to participate in this study because they and their partner are patients of the MGH Fertility Center, trying to get pregnant, either naturally or by undergoing Intrauterine Insemination (IUI) and/or In Vitro Fertilization (IVF).

Primary Outcome

To determine the association of a mixture of paternal urinary concentrations of phthalate metabolites, BPA and parabens with the primary outcomes of implantation failure and live birth, and the secondary outcomes of chemical pregnancy (with no subsequent clinical pregnancy) and spontaneous abortion.

Conditions Studied

Interventions

  • OTHER Completion questionnaires/providing biological samples

Study Locations (1)

Massachusetts

  • Harvard School of Public Health - Boston

Trial Details

FieldValue
Enrollment Target 1,474 participants
Start Date 1999-10
Est. Completion 2020-09

What the finished NCT00011713 record still lists

NCT00011713 is an observational study that tracks outcomes without assigning an intervention. Its 1,474 participants enrollment target places it among the larger protocols in the corpus, below the 7,570-participant average among 74 other Infertility trials with a reported enrollment target (81% lower).

The record links to 1 condition, with Infertility appearing as the primary indexed condition, and to 1 intervention - of which Completion questionnaires/providing biological samples is the first listed.

NCT00011713 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00011713 about?

NCT00011713 is a clinical study titled "Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes". The purpose of the study is to investigate the relationship between environmental agents and reproductive health. Environmental agents of interest include exposure to chemicals such as polychlorinated biphenyls (PCBs), flame retardants, dioxins, bisphenol A, phthalates, pesticides, and metals like l...

What is the current status of trial NCT00011713?

This trial is currently completed. The enrollment target is 1,474 participants. The study started on 1999-10. Estimated completion is 2020-09.

What conditions does trial NCT00011713 study?

This clinical trial studies the following conditions: Infertility.

What interventions are being tested in trial NCT00011713?

The interventions under investigation include: Completion questionnaires/providing biological samples (OTHER).

Who is sponsoring clinical trial NCT00011713?

This trial is sponsored by National Institute of Environmental Health Sciences (NIEHS), which has 145 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00011713 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Infertility

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00011713's enrollment target sits among peer trials

1,474 11th of 74 higher than 64 of 74 other Infertility trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Infertility trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00011713, the US trial registry maintained by the National Library of Medicine. NCT00011713 (large enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.