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NCT00501800 · ClinicalTrials.gov registry record
Genetic Epidemiology of Ovarian Aging
A clinical trial of Infertility, sponsored by University of California, San Francisco.
- Active
- Registry status
- 1,250
- Enrollment target
- 1
- Study location
NCT00501800 is a study of Infertility that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 1,250 participants, below the 7,573-participant average among 74 other Infertility trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00501800, a study of Infertility, is active but no longer recruiting, sponsored by University of California, San Francisco.
- ACTIVE NOT RECRUITING
- Registry status
- 1,250 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to identify clinical and genetic markers of ovarian aging. In this process, we will evaluate environmental factors that may affect fertility and the age at which fertility declines, and may influence the age at which women enter menopause. Wide variability exists between women both in the age at which menopause occurs and the rate of decline in oocyte number and reproductive capability. As the loss of ovarian function has profound impact on women's hormonal milieu and their subsequent risk for the development of disease, improving our understanding of the factors that determine the timing and rate of reproductive aging is critical to improving quality of life for all women. In addition, improving our understanding of reproductive aging has profound economic, and social, implications given the complex choices women face regarding the timing of childbearing and the growing burden of infertility. While the inter-individual variability in age at menopause has a large genetic component and possible environmental influences, to date no studies have addressed the relationship between oocyte number as reflected by antral follicle count (AFC) and genetic inheritance. We hypothesize that ovarian aging, as reflected by antral follicle count, is largely determined by common genetic polymorphisms that impact the initial oocyte endowment and/or the rate of oocyte loss over time thus lowering antral follicle count for any given age. We further hypothesize that antral follicle count will be an improved marker of ovarian aging. Thus, we propose a study of the genetic and environmental factors that influence age-specific variability in antral follicle count.
Conditions Studied
Study Locations (1)
California
- University of California San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,250 participants |
| Start Date | 2006-11 |
| Est. Completion | 2025-07 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00501800
The ClinicalTrials.gov registry entry for NCT00501800 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 1,250 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 7,573-participant average among 74 other Infertility trials with a reported enrollment target (83% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Infertility appearing as the primary indexed condition, and to 0 interventions.
NCT00501800 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT00501800 about?
NCT00501800 is a clinical study titled "Genetic Epidemiology of Ovarian Aging". The purpose of this study is to identify clinical and genetic markers of ovarian aging. In this process, we will evaluate environmental factors that may affect fertility and the age at which fertility declines, and may influence the age at which women enter menopause. Wide variability exists between...
What is the current status of trial NCT00501800?
This trial is currently active not recruiting. The enrollment target is 1,250 participants. The study started on 2006-11. Estimated completion is 2025-07.
What conditions does trial NCT00501800 study?
This clinical trial studies the following conditions: Infertility.
Who is sponsoring clinical trial NCT00501800?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00501800 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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