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ClinicalTrials.gov 56 recruiting now early-phase tilt #7 of 28,963 conditions

HIV Infections: early-phase trial registry

56 of 615 indexed HIV Infections trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #7 of 28,963 conditions by registered trial count.

615 US clinical trials · 56 currently recruiting · #7 of 28,963 conditions by registered trial count

HIV Infections: 615 US clinical trials tracked, 56 recruiting.

HIV Infections is the subject of 615 registered US clinical trials on ClinicalTrials.gov, 56 of them currently open to new participants. 92 are in Phase 3-4 (later-stage) and 266 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 195 of these trials.

Open enrollment, early-phase tilt

HIV Infections has 615 registered US clinical trials, 56 of them open to new participants right now, about 9% of the total.

56
recruiting participants now
9%
of trials open to enrollment
92
in Phase 3-4 (later-stage)
195
top sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Corpus placement: #7 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for HIV Infections on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. HIV Infections is recruiting below its size-band peers.

    56 of 615 indexed trials (9.1%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates HIV Infections research.

    National Institute of Allergy and Infectious Diseases (NIAID) accounts for 195 of 615 trials (31.7%). 173 distinct sponsors appear on at least one study for this condition label.

  3. Typical HIV Infections enrolment sits around 100 participants.

    Median target enrolment is 100 among the 543 trials that report a genuine target (sentinel values excluded). 267 of those (49.2%) plan for fewer than 100 participants.

  4. HIV Infections research is mostly interventional.

    549 interventional and 66 observational studies make up this index (89.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1157Phase 2109Phase 369Phase 423

Open and recent trials

615 total, page 10 of 13

COMPLETED Phase 1 29 participants

Determining Responses to Two Different Vaccines in HIV and HCV Infected Individuals

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00393276

COMPLETED Phase 1 29 participants

Pharmacokinetic (PK) Study of Single-dose Rosuvastatin and Tipranavir/Ritonavir in Healthy Subjects

Johns Hopkins University

NCT00344123

COMPLETED Phase 1 28 participants

A Study of Nitazoxanide in the Treatment of AIDS-Related Diarrhea

Unimed Pharmaceuticals

NCT00002444

COMPLETED Phase 1 28 participants

Effects of Etravirine on Endothelial Function in HIV-uninfected Adults: A Pilot Study

Indiana University

NCT00871234

COMPLETED Phase 1 28 participants

Drug Interaction - Oral Contraceptive

Bristol-Myers Squibb

NCT00399685

COMPLETED NA 27 participants

Using Implementation Science to Increase Pre-Exposure Prophylaxis Uptake Among African American Women

Johns Hopkins Bloomberg School of Public Health

NCT05139069

COMPLETED Phase 1 27 participants

Evaluating the Immunogenicity of the AIDSVAX B/E Vaccine and the MVA/HIV62B Vaccine in Healthy, HIV-1-Uninfected Adults Who Previously Received MVA/HIV62B in DNA/MVA or MVA/MVA Regimens in HVTN 205

National Institute of Allergy and Infectious Diseases (NIAID)

NCT02852005

COMPLETED Phase 1 27 participants

A Pharmacokinetic Study of L-697,661 Alone and in Combination With Zidovudine

Merck Sharp & Dohme

NCT00000628

COMPLETED Phase 1 27 participants

A Study to Test the Safety of Recombinant Interleukin-2 (rIL-2) in HIV-Infected Children

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000849

COMPLETED Phase 2 27 participants

A Study of Targretin Capsules in Patients With AIDS-Related Kaposi's Sarcoma

Ligand Pharmaceuticals

NCT00002212

COMPLETED 27 participants

ADAPT-POL New Orleans: Adaptation of Prevention Techniques With Popular Opinion Leader

Centers for Disease Control and Prevention

NCT00252109

COMPLETED Phase 4 27 participants

Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program

University of Miami

NCT04650269

COMPLETED Phase 3 26 participants

Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients With AIDS Who Have Not Had Success With Acyclovir

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000985

COMPLETED Phase 1 26 participants

A Study to Evaluate the Safety and Tolerance of Stavudine (d4T) in Combination With Lamivudine (3TC) in HIV-Positive Pregnant Women and Their Infants

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000878

COMPLETED Phase 1 26 participants

A Two-part Study to Compare a Tablet and Capsule Formulation of GSK2838232 With and Without Food, and to Assess the Safety and Drug Levels of Repeated Once-daily Doses of GSK2838232 Without Ritonavir

GlaxoSmithKline

NCT03234036

COMPLETED NA 25 participants

Four-Drug Combination Therapy With Zidovudine, Lamivudine, 1592U89 (Abacavir), and 141W94 (Amprenavir) in HIV-Infected Patients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00006617

COMPLETED NA 25 participants

Contingency Management for Cannabis Use for Persons With HIV

The University of Texas Health Science Center at San Antonio

NCT04866004

COMPLETED NA 25 participants

Suppression of Cytomegalovirus Retinitis Utilizing High Dose Intravenous Acyclovir and Oral Zidovudine in Patients With AIDS

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000693

COMPLETED Phase 4 25 participants

Pilot Study Evaluating Interruption of Enfuvirtide (Fuzeon, T20) in Patients With Enfuvirtide Resistance

University of California, San Francisco

NCT00187551

COMPLETED Phase 1 25 participants

Effect of HIV Protease Inhibitor Drugs on Glucose and Insulin Metabolism

Bristol-Myers Squibb

NCT00135434

COMPLETED Phase 2 25 participants

Safety and Effectiveness of Giving an Anti-HIV Drug Combination of Adefovir Dipivoxil Plus Didanosine Plus Efavirenz Plus Lamivudine Once Daily to HIV-Infected Patients

Gilead Sciences

NCT00002234

COMPLETED Phase 1 25 participants

A Phase I Multicenter Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000956

COMPLETED Phase 2 25 participants

Immune Response to a Therapeutic HIV Vaccine Followed by Treatment Interruption in Patients With Acute or Recent HIV Infection

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00183261

COMPLETED Phase 2 25 participants

Maraviroc Plus Darunavir/Ritonavir for Treatment-Naïve Patients Infected With R5-tropic HIV-1

Northwestern University

NCT00993148

COMPLETED Phase 1 24 participants

The Safety and Effectiveness of Nevirapine Plus Nelfinavir in HIV-1 Infected Patients Who Have Taken Stavudine

Boehringer Ingelheim

NCT00002381

COMPLETED Phase 2 24 participants

A Study of Delavirdine Mesylate in Combination With Other Anti-HIV Drugs in HIV-Infected Children and Babies

Pharmacia and Upjohn

NCT00002210

COMPLETED Phase 1 24 participants

Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult Participants

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03934541

COMPLETED Phase 1 24 participants

A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000788

COMPLETED NA 24 participants

A Study of Stem Cells and Filgrastim

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001071

COMPLETED Phase 1 24 participants

Development of a New HIV Vaccine

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00051922

COMPLETED Phase 1 24 participants

A Study to Assess Relative Bioavailability and Food Effect of New Formulations of GSK2248761

ViiV Healthcare

NCT01031472

COMPLETED NA 24 participants

A Study of Granulocyte Colony-Stimulating Factor Plus Recombinant Erythropoietin Plus Zidovudine in Patients With AIDS or AIDS-Related Complex

Amgen

NCT00002281

COMPLETED Phase 1 24 participants

A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and Didanosine

Hoffmann-La Roche

NCT00002096

COMPLETED Phase 1 24 participants

A Study to Evaluate the Safety and Tolerance of Combination Anti-HIV Drug Therapy (Indinavir, Lamivudine, and Zidovudine) in HIV-Positive Pregnant Women and Their Infants

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000944

COMPLETED Phase 2 22 participants

Treatment of Hepatitis C in Hemophilic Patients With HIV

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00055341

COMPLETED Phase 1 22 participants

DDI HV (ATV - Merck)

Bristol-Myers Squibb

NCT00518297

COMPLETED Phase 1 21 participants

Blood Levels of Tenofovir Gel in HIV Uninfected Pregnant Women Planning Cesarean Delivery

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00540605

COMPLETED 21 participants

Central Nervous System Disease in HIV-infected Children on HAART

National Cancer Institute (NCI)

NCT00110331

COMPLETED Phase 1 21 participants

Pharmacokinetics of Efavirenz in HIV-1 Infected Subjects With Hepatic Impairment

Bristol-Myers Squibb

NCT00162097

COMPLETED Phase 1 21 participants

Study of the Absorption, Metabolism, and Route of Elimination of a Novel Class of Anti-HIV 1 Drugs (BMS-955176) in Humans.

ViiV Healthcare

NCT02206711

COMPLETED Phase 4 21 participants

Treatment of Acute Hepatitis C Virus in HIV Co-Infection

University of California, San Francisco

NCT00845676

COMPLETED Phase 1 20 participants

Zidovudine and Lamivudine Given Once Versus Twice Daily

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00014014

COMPLETED NA 20 participants

Effect of Diet-induced Weight Loss on HIV-associated Metabolic Syndrome

Washington University School of Medicine

NCT00857298

COMPLETED 20 participants

A Pilot Study of Non-Hodgkin's Lymphoma: Chemotherapy and Blood Levels of Organochlorines

National Cancer Institute (NCI)

NCT00001571

COMPLETED Phase 1 20 participants

Study of the HIV gp120/NefTat/AS02A Vaccine to Treat Individuals With Chronic HIV-1 Infection on Highly Active Antiretroviral Therapy (HAART)

Marcus Altfeld, M.D., Ph.D.

NCT00117429

COMPLETED NA 20 participants

The Effects of Zidovudine on the Blood of HIV-Infected Patients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000965

COMPLETED Phase 1 20 participants

Antihyperlipidemic Effects of Oyster Mushrooms

National Center for Complementary and Integrative Health (NCCIH)

NCT00069524

COMPLETED Phase 3 20 participants

Changes in Lipids and Safety of Raltegravir in HIV+ Patients With Hyperlipidemia While on Current Standard Therapy

The Miriam Hospital

NCT00887653

COMPLETED Phase 1 20 participants

The Safety and Effectiveness of Zidovudine Plus Adefovir in HIV-Infected Patients

Gilead Sciences

NCT00002326

COMPLETED Phase 1 20 participants

Interluekin-7 to Treat HIV-Infected People Receiving Antiretroviral Treatment

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00105417

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Phase Distribution

PhaseTrial count
Phase 1 157
Phase 2 109
Phase 3 69
Phase 4 23

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for HIV Infections right now

56 recruiting of 615 indexed (9% open).

Phase mix: 92 late (III/IV) vs 266 early (I/II) (early-phase heavy).

Top sponsor: National Institute of Allergy and Infectious Diseases (NIAID) (195 trials), 9 others listed. 50 shown below, recruiting first. #7 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for HIV Infections?

PlainTrial tracks 615 US clinical trials for HIV Infections, of which 56 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for HIV Infections?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.