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NCT00183261 · ClinicalTrials.gov registry record · Phase 2

Immune Response to a Therapeutic HIV Vaccine Followed by Treatment Interruption in Patients With Acute or Recent HIV Infection

A Phase 2 study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 2
Development phase
25
Enrollment target
20
Study locations

NCT00183261 is a Phase 2 study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 25 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (94% lower). The trial reports 20 study locations across 9 states.

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The verdict

NCT00183261, a Phase 2 study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 2
Development phase
25 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to determine whether the HIV vaccine MRKAd5 HIV-1 gag/pol/nef followed by treatment interruption can increase immune system function in adults with acute or recent HIV infection who have started taking anti-HIV drugs.

Conditions Studied

Interventions

  • BIOLOGICAL MRKAd5 HIV-1 gag/pol/nef
  • BIOLOGICAL MRKAd5 HIV-1 gag/pol/nef placebo

Study Locations (20)

New South Wales

  • 407 Doctors CRS - Surry Hills
  • Holdsworth House Medical Practice CRS - Darlinghurst
  • St. Vincent's Hospital CRS - Darlinghurst
  • Taylor Square Private Clinic CRS - Darlinghurst
  • AIDS Research Initiative, Darlinghurst CRS - Darlinghurst

North Carolina

  • Unc Aids Crs - Chapel Hill
  • UNC, Chapel Hill AIEDRP - Chapel Hill
  • Duke Univ. Med. Ctr. Adult CRS - Durham
  • Dumc Aiedrp - Durham

California

  • Ucsd Aiedrp - San Diego
  • Ucsf Aiedrp - San Francisco
  • LA Biomedical Research Institute at Harbor-UCLA AIEDRP - Torrance

New York

  • Beth Israel Med. Ctr., ACTU - New York
  • Aaron Diamond AIDS Research Ctr. AIEDRP - New York

Other

  • 407 Doctors (Australia) AIEDRP - Sydney
  • AIDS Research Initiative (Australia) AIEDRP - Sydney

Colorado

  • Univ. of Colorado Health Sciences Ctr. AIEDRP - Denver

Massachusetts

  • Fenway Community Health Ctr. CRS - Boston

Missouri

  • Washington U CRS - St Louis

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2006-03
Est. Completion 2010-10
Phase Phase 2

What the Registry Record Tells You About NCT00183261

The ClinicalTrials.gov registry entry for NCT00183261 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (94% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 2 interventions - of which MRKAd5 HIV-1 gag/pol/nef is the first listed.

NCT00183261 reports 20 study locations spanning 9 distinct geographic areas - top geographies include New South Wales, North Carolina, California.

Frequently Asked Questions

What is clinical trial NCT00183261 about?

NCT00183261 is a clinical study titled "Immune Response to a Therapeutic HIV Vaccine Followed by Treatment Interruption in Patients With Acute or Recent HIV Infection". The purpose of this study is to determine whether the HIV vaccine MRKAd5 HIV-1 gag/pol/nef followed by treatment interruption can increase immune system function in adults with acute or recent HIV infection who have started taking anti-HIV drugs.

What is the current status of trial NCT00183261?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2006-03. Estimated completion is 2010-10.

What conditions does trial NCT00183261 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT00183261?

The interventions under investigation include: MRKAd5 HIV-1 gag/pol/nef (BIOLOGICAL), MRKAd5 HIV-1 gag/pol/nef placebo (BIOLOGICAL).

Who is sponsoring clinical trial NCT00183261?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00183261 being conducted?

This trial has 20 study locations across California, Colorado, Massachusetts, Missouri, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.