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NCT00001571 · ClinicalTrials.gov registry record
A Pilot Study of Non-Hodgkin's Lymphoma: Chemotherapy and Blood Levels of Organochlorines
A clinical trial of HIV Infections and Lymphoma, Non-Hodgkin, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- 20
- Enrollment target
- 1
- Study location
NCT00001571: Completed study of HIV Infections and Lymphoma, Non-Hodgkin, sponsored by National Cancer Institute (NCI).
NCT00001571 is a study of HIV Infections and Lymphoma, Non-Hodgkin that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 20 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001571, a study of HIV Infections and Lymphoma, Non-Hodgkin, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Non-Hodgkin's lymphoma (NHL) is the third most rapidly increasing cancer in the United States. HIV-related NHL is responsible for some of the increase since the early 1980s. However, it cannot explain the steady increase in the incidence rates in earlier years, nor the entire increase shown recently. A possible role of environmental exposures is receiving attention. One possibility is that exposure to organochlorines (OCs) may be related to the occurrence of NHL. NCI is currently designing a large population-based case-control study to investigate this hypothesis further by analyzing OC levels in blood collected at the time of interview from cases of NHL and their matched controls. At the time of these interviews, cases in the main case-control study would most likely have already received chemotherapy. If chemotherapy changes the blood levels of OCs, this may lead to misclassification of exposure among cases and eventually to biased risk estimates. The purpose of this pilot study is to estimate the bias due to measuring the serum levels of OCs in cases during or after chemotherapy. Twenty newly diagnosed patients will be recruited for the study. From each patient, four consecutive blood samples, one prior to, two during, and one after chemotherapy, will be collected. Forty pairs of pre-existing cryopreserved serum samples (pre- and post-treatment) taken from the NHL patients who participated in an earlier NCI clinical study will also be included in this study. Samples will be assayed for OC levels. The results will be used to plan and to interpret another large case-control study (the main study).
Conditions Studied
Study Locations (1)
Maryland
- National Cancer Institute (NCI) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 1997-02 |
| Est. Completion | 2000-12 |
What the finished NCT00001571 record still lists
NCT00001571 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (96% lower).
The record links to 3 conditions, with HIV Infections appearing as the primary indexed condition, and to 0 interventions.
NCT00001571 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001571 about?
NCT00001571 is a clinical study titled "A Pilot Study of Non-Hodgkin's Lymphoma: Chemotherapy and Blood Levels of Organochlorines". Non-Hodgkin's lymphoma (NHL) is the third most rapidly increasing cancer in the United States. HIV-related NHL is responsible for some of the increase since the early 1980s. However, it cannot explain the steady increase in the incidence rates in earlier years, nor the entire increase shown recently...
What is the current status of trial NCT00001571?
This trial is currently completed. The enrollment target is 20 participants. The study started on 1997-02. Estimated completion is 2000-12.
What conditions does trial NCT00001571 study?
This clinical trial studies the following conditions: HIV Infections, Lymphoma, Non-Hodgkin, Lymphoma, AIDS-Related.
Who is sponsoring clinical trial NCT00001571?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001571 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00001571's enrollment target sits among peer trials
20 487th of 542 higher than 42 of 542 other HIV Infections trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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