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NCT00000965 · ClinicalTrials.gov registry record · NA

The Effects of Zidovudine on the Blood of HIV-Infected Patients

A NA study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT00000965: Completed NA study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00000965 is a NA study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 20 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00000965, a NA study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

To define the pharmacokinetic parameters (blood levels) of total phosphorylated zidovudine (AZT) in peripheral blood mononuclear cells (PBMC) from HIV-infected patients. Despite an understanding of the serum (or plasma) pharmacokinetics (blood levels) of AZT, a therapeutic concentration range and optimal dosing interval have not yet been determined.

Conditions Studied

Interventions

  • DRUG Zidovudine

Study Locations (1)

Ohio

  • Univ of Cincinnati - Cincinnati

Trial Details

FieldValue
Enrollment Target 20 participants
Phase NA

What the finished NCT00000965 record still lists

NCT00000965 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (96% lower).

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which Zidovudine is the first listed.

NCT00000965 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT00000965 about?

NCT00000965 is a clinical study titled "The Effects of Zidovudine on the Blood of HIV-Infected Patients". To define the pharmacokinetic parameters (blood levels) of total phosphorylated zidovudine (AZT) in peripheral blood mononuclear cells (PBMC) from HIV-infected patients. Despite an understanding of the serum (or plasma) pharmacokinetics (blood levels) of AZT, a therapeutic concentration range and o...

What is the current status of trial NCT00000965?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants.

What conditions does trial NCT00000965 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT00000965?

The interventions under investigation include: Zidovudine (DRUG).

Who is sponsoring clinical trial NCT00000965?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00000965 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00000965's enrollment target sits among peer trials

20 487th of 542 higher than 42 of 542 other HIV Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00000965, the US trial registry maintained by the National Library of Medicine. NCT00000965 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.