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NCT00993148 · ClinicalTrials.gov registry record · Phase 2

Maraviroc Plus Darunavir/Ritonavir for Treatment-Naïve Patients Infected With R5-tropic HIV-1

A Phase 2 study of HIV Infections and HIV-1-infection, sponsored by Northwestern University.

Completed
Registry status
Phase 2
Development phase
25
Enrollment target
5
Study locations

NCT00993148 is a Phase 2 study of HIV Infections and HIV-1-infection that has completed, run by Northwestern University. The registered enrollment target is 25 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (94% lower). The trial reports 5 study locations across 4 states.

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The verdict

NCT00993148, a Phase 2 study of HIV Infections and HIV-1-infection, has completed, sponsored by Northwestern University.

COMPLETED
Registry status
Phase 2
Development phase
25 participants
Enrollment target
5
Study locations

Study Summary

The objective of this study is to evaluate the safety and efficacy of a novel combination antiretroviral therapy regimen consisting of maraviroc plus darunavir/ritonavir in treatment-naive patients infected with R5-tropic HIV-1. The hypothesis is that in treatment-naive subjects infected with R5-tropic HIV-1, combination antiretroviral therapy with maraviroc plus darunavir/ritonavir is well tolerated and efficacious.

Interventions

  • DRUG ritonavir
  • DRUG darunavir
  • DRUG maraviroc

Study Locations (5)

Illinois

  • Northwestern University - Chicago
  • CORECenter - Chicago

California

  • Quest Clinical Research - San Francisco

Florida

  • University of Miami - Miami

Nebraska

  • University of Nebraska - Omaha

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2010-05
Est. Completion 2013-04
Phase Phase 2

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT00993148

The ClinicalTrials.gov registry entry for NCT00993148 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (94% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 3 interventions - of which ritonavir is the first listed.

NCT00993148 reports 5 study locations spanning 4 distinct geographic areas - top geographies include Illinois, California, Florida.

Frequently Asked Questions

What is clinical trial NCT00993148 about?

NCT00993148 is a clinical study titled "Maraviroc Plus Darunavir/Ritonavir for Treatment-Naïve Patients Infected With R5-tropic HIV-1". The objective of this study is to evaluate the safety and efficacy of a novel combination antiretroviral therapy regimen consisting of maraviroc plus darunavir/ritonavir in treatment-naive patients infected with R5-tropic HIV-1. The hypothesis is that in treatment-naive subjects infected with R5-tro...

What is the current status of trial NCT00993148?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2010-05. Estimated completion is 2013-04.

What conditions does trial NCT00993148 study?

This clinical trial studies the following conditions: HIV Infections, HIV-1-infection.

What interventions are being tested in trial NCT00993148?

The interventions under investigation include: ritonavir (DRUG), darunavir (DRUG), maraviroc (DRUG).

Who is sponsoring clinical trial NCT00993148?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00993148 being conducted?

This trial has 5 study locations across California, Florida, Illinois, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.