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NCT00162097 · ClinicalTrials.gov registry record · Phase 1

Pharmacokinetics of Efavirenz in HIV-1 Infected Subjects With Hepatic Impairment

A Phase 1 study of HIV Infections and Hepatic Impairment, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 1
Development phase
21
Enrollment target
4
Study locations

NCT00162097 is a Phase 1 study of HIV Infections and Hepatic Impairment that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 21 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (95% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT00162097, a Phase 1 study of HIV Infections and Hepatic Impairment, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 1
Development phase
21 participants
Enrollment target
4
Study locations

Study Summary

The purpose of the study was to assess the steady-state pharmacokinetics (PK) of efavirenz (EFV) in human immunodeficiency virus type 1 (HIV-1) infected subjects on stable antiretroviral regimens containing EFV, and having selected degrees of hepatic impairment or normal hepatic function.

Interventions

  • DRUG efavirenz containing antiretroviral regimen

Study Locations (4)

Maryland

  • Johns Hopkins University School Of Medicine - Baltimore

Texas

  • Uthscsa - San Antonio

Virginia

  • Virginia Commonwealth University Health Systems - Richmond

Other

  • Local Institution - Milan

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2004-11
Est. Completion 2008-03
Phase Phase 1

Sponsor

Bristol-Myers Squibb

1,025 total trials

What the Registry Record Tells You About NCT00162097

The ClinicalTrials.gov registry entry for NCT00162097 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (95% lower). The listed sponsor is Bristol-Myers Squibb, which has 1,025 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which efavirenz containing antiretroviral regimen is the first listed.

NCT00162097 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Maryland, Texas, Virginia.

Frequently Asked Questions

What is clinical trial NCT00162097 about?

NCT00162097 is a clinical study titled "Pharmacokinetics of Efavirenz in HIV-1 Infected Subjects With Hepatic Impairment". The purpose of the study was to assess the steady-state pharmacokinetics (PK) of efavirenz (EFV) in human immunodeficiency virus type 1 (HIV-1) infected subjects on stable antiretroviral regimens containing EFV, and having selected degrees of hepatic impairment or normal hepatic function.

What is the current status of trial NCT00162097?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2004-11. Estimated completion is 2008-03.

What conditions does trial NCT00162097 study?

This clinical trial studies the following conditions: HIV Infections, Hepatic Impairment.

What interventions are being tested in trial NCT00162097?

The interventions under investigation include: efavirenz containing antiretroviral regimen (DRUG).

Who is sponsoring clinical trial NCT00162097?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00162097 being conducted?

This trial has 4 study locations across Maryland, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.