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ClinicalTrials.gov 1 recruiting now early-phase tilt small index

Acute Lung Injury: early-phase trial registry

1 of 11 indexed Acute Lung Injury trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 1 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Acute Lung Injury: 11 US clinical trials tracked, 1 recruiting.

Acute Lung Injury is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Altor BioScience, running 2 of these trials.

Enrollment posture brief

Registry condition acute-lung-injury

OPEN 1 | RECR 9% | LATE 0 | EARLY 7 | RANK #1577 | SPON 2

Nearest open-share peer: Advanced Cancers (9% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%Adenocarcinoma of the Pancre18.2%Acute Lung Injury (this)9%
Open-enrollment share among volume-matched conditions near Acute Lung Injury

Acute Lung Injury lists 1 open slots (9% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Acute Lung Injury on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Acute Lung Injury is recruiting below its size-band peers.

    1 of 11 indexed trials (9.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Acute Lung Injury research.

    Altor BioScience accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Acute Lung Injury trials plan to enrol fewer than 100 people.

    Median target enrolment is 56 among the 11 trials that report a genuine target (sentinel values excluded). 7 of those (63.6%) plan for fewer than 100 participants.

  4. Acute Lung Injury research is mostly interventional.

    10 interventional and 1 observational studies make up this index (90.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 24

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 2 56 participants

Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients

Implicit Bioscience

NCT06513949

COMPLETED Phase 1 600 participants

A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury

Eli Lilly and Company

NCT00036062

COMPLETED Phase 2 160 participants

Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure

Fred Hutchinson Cancer Center

NCT01335932

COMPLETED Phase 2 150 participants

Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome

Altor BioScience

NCT00879606

COMPLETED NA 128 participants

Lung Protective Ventilation in Pulmonary Thromboendarterectomy (PTE) Patients

University of California, San Diego

NCT00747045

COMPLETED NA 63 participants

Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury

Beth Israel Deaconess Medical Center

NCT00127491

COMPLETED Phase 2 43 participants

CALIPSO: Calfactant for Acute Lung Injury in Pediatric Stem Cell Transplant and Oncology Patients

Milton S. Hershey Medical Center

NCT00999713

COMPLETED Phase 1 20 participants

Iloprost Effects on Gas Exchange and Pulmonary Mechanics

University of Oklahoma

NCT01274481

COMPLETED Phase 1 18 participants

Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome

Altor BioScience

NCT01438853

COMPLETED NA 12 participants

Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury

Boston Children's Hospital

NCT00830284

COMPLETED 8 participants

The ASTERS Study: Assessing the Role of Sphingolipids in AcuTE Respiratory Distress Syndrome (ARDS)

Sturgill

NCT03654352

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 4

Named interventions

Most-linked intervention names on Acute Lung Injury records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
IV Ganciclovir Drug
1 trials
Sivelestat Drug
1 trials
ALT-836 Drug
1 trials
TNX-832 Biological
1 trials
Air placebo Other
1 trials
Calfactant Drug
1 trials
Recruitment maneuver Procedure
1 trials

US sites by state

Facility locations filed on Acute Lung Injury trials. A trial with sites in several states counts in each.

Massachusetts 5 trials
California 4 trials
Ohio 3 trials
North Carolina 3 trials
Illinois 3 trials
Washington 2 trials
Texas 2 trials
Pennsylvania 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Acute Lung Injury page

11 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 1 Acute Lung Injury trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Altor BioScience sponsors the most Acute Lung Injury trials on record, review their full trial history before evaluating a specific study. See Altor BioScience's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Lung Injury condition card totals 11 registered trials; most-linked intervention Placebo; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.