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2026 data Public-data reference. official source

Hematopoietic Stem Cell Transplantation

Open-data reference.

27 US clinical trials · 14 currently recruiting

Active & Recent Trials

RECRUITING 250,000 participants

The Collection and Storage of Umbilical Cord Blood for Transplantation

M.D. Anderson Cancer Center

NCT01728545

RECRUITING 2,000 participants

Long-Term Follow-up of People Undergoing Hematopoietic Stem Cell Transplantation

National Cancer Institute (NCI)

NCT03000244

RECRUITING Phase 1 260 participants

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

National Cancer Institute (NCI)

NCT05436418

RECRUITING NA 222 participants

Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant

National Cancer Institute (NCI)

NCT05605574

RECRUITING Phase 2 125 participants

Dietary Manipulation of the Microbiome-metabolomic Axis for Mitigating GVHD in Allo HCT Patients

University of Michigan Rogel Cancer Center

NCT02763033

RECRUITING NA 90 participants

Supportive Care Intervention for Outpatient Stem Cell Transplant Patients

Victor Wang

NCT06564233

RECRUITING NA 60 participants

Cultural Tailoring and Pilot Testing of an Inpatient Yoga Therapy Program for Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation in India, Tanzania, and the United States

M.D. Anderson Cancer Center

NCT05681026

RECRUITING Phase 2 54 participants

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

National Cancer Institute (NCI)

NCT05027945

RECRUITING NA 50 participants

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)

Nationwide Children's Hospital

NCT06082947

RECRUITING NA 35 participants

Employment Support After Hematopoietic Stem Cell Transplantation

MGH Institute of Health Professions

NCT06494423

RECRUITING 30 participants

Metagenomics Next-generation Sequencing Approach to Detect Microbial DNA/RNA Overtime in Individuals Undergoing Hematopoietic Stem Cell Transplant

National Institutes of Health Clinical Center (CC)

NCT06904053

RECRUITING Early Phase 1 20 participants

Prevention of Graft Rejection in Hematopoietic Stem Cell Transplant (HSCT) Recipients

Children's Hospital Medical Center, Cincinnati

NCT07244419

RECRUITING Phase 1 20 participants

Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors

Children's Hospital Medical Center, Cincinnati

NCT07375290

RECRUITING Phase 2 18 participants

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

Omeros Corporation

NCT05855083

ACTIVE NOT RECRUITING NA 230 participants

Multimodal Sexual Dysfunction Intervention In HCT

Massachusetts General Hospital

NCT03803696

ACTIVE NOT RECRUITING NA 20 participants

Standardization of CD3+ T Cell Dose for Patients Receiving Allogeneic Peripheral Blood Stem Cell Transplantation From Matched Related Donors

University of Alabama at Birmingham

NCT00959140

ACTIVE NOT RECRUITING NA 18 participants

Art and Physical Therapy in Pediatric HCT

Medical University of South Carolina

NCT05441670

COMPLETED 637 participants

Protocol For Collecting Long-Term Follow-Up Data On Recipients of Bone Marrow and Blood Stem Cell Transplant

St. Jude Children's Research Hospital

NCT00674882

COMPLETED Phase 2 195 participants

Problem-Solving Education for Caregivers and Patients During Stem Cell Transplant

National Institutes of Health Clinical Center (CC)

NCT00766883

COMPLETED 112 participants

Iron Overload in Patients Undergoing Donor Stem Cell Transplant

Masonic Cancer Center, University of Minnesota

NCT00888316

COMPLETED 100 participants

Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant

Vanderbilt University

NCT00179049

COMPLETED Phase 2 66 participants

High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation

UNC Lineberger Comprehensive Cancer Center

NCT03263442

COMPLETED NA 54 participants

Treating Cancer-Related Fatigue Through Systematic Light Exposure

Icahn School of Medicine at Mount Sinai

NCT01873794

COMPLETED 38 participants

Comparison of Gut Microbiota, Inflammation and Symptoms Following Allogeneic HSCT

University of Florida

NCT02398708

COMPLETED Phase 2 30 participants

Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia

National Heart, Lung, and Blood Institute (NHLBI)

NCT00029380

COMPLETED 29 participants

Evaluation of Malglycemia Via Continuous Glucose Monitoring in the Pediatric HSCT Population

University of Colorado, Denver

NCT03037671

COMPLETED Phase 1 19 participants

Dose Escalation Study Of Palifermin in Pediatric Research Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

St. Jude Children's Research Hospital

NCT00701688

Phase Distribution

PhaseTrial count
Early Phase 1 4
Phase 2 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hematopoietic Stem Cell Transplantation Trial Landscape

ClinicalTrials.gov lists 27 US studies indexed under Hematopoietic Stem Cell Transplantation, and 14 of those are currently open to recruitment — roughly 52% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Hematopoietic Stem Cell Transplantation shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 10 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Hematopoietic Stem Cell Transplantation is led by National Cancer Institute (NCI) with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 27 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hematopoietic Stem Cell Transplantation?

PlainTrial tracks 27 US clinical trials for Hematopoietic Stem Cell Transplantation, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hematopoietic Stem Cell Transplantation?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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