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NCT07375290 · ClinicalTrials.gov registry record · Phase 1

Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors

A Phase 1 study of Hematopoietic Stem Cell Transplantation, sponsored by Children's Hospital Medical Center, Cincinnati.

Recruiting
Registry status
Phase 1
Development phase
20
Enrollment target
1
Study location

NCT07375290 is a Phase 1 study of Hematopoietic Stem Cell Transplantation that is actively recruiting participants, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 20 participants, below the 9,789-participant average among 26 other Hematopoietic Stem Cell Transplantation trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07375290, a Phase 1 study of Hematopoietic Stem Cell Transplantation, is actively recruiting participants, sponsored by Children's Hospital Medical Center, Cincinnati.

RECRUITING
Registry status
Phase 1
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

The purpose of this pilot study is to investigate the safety and preliminarily assess efficacy of early intervention with zoledronate in high risk pediatric hematopoietic stem cell transplantation (HSCT) patients to prevent the development of bone disease and fractures and reduce potential pain and suffering.

Interventions

  • DRUG Zoledronate

Study Locations (1)

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-02
Est. Completion 2028-11
Phase Phase 1

What the Registry Record Tells You About NCT07375290

The ClinicalTrials.gov registry entry for NCT07375290 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 9,789-participant average among 26 other Hematopoietic Stem Cell Transplantation trials with a reported enrollment target (100% lower). The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hematopoietic Stem Cell Transplantation appearing as the primary indexed condition, and to 1 intervention - of which Zoledronate is the first listed.

NCT07375290 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT07375290 about?

NCT07375290 is a clinical study titled "Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors". The purpose of this pilot study is to investigate the safety and preliminarily assess efficacy of early intervention with zoledronate in high risk pediatric hematopoietic stem cell transplantation (HSCT) patients to prevent the development of bone disease and fractures and reduce potential pain and ...

What is the current status of trial NCT07375290?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2026-02. Estimated completion is 2028-11.

What conditions does trial NCT07375290 study?

This clinical trial studies the following conditions: Hematopoietic Stem Cell Transplantation.

What interventions are being tested in trial NCT07375290?

The interventions under investigation include: Zoledronate (DRUG).

Who is sponsoring clinical trial NCT07375290?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07375290 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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