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NCT07375290 · ClinicalTrials.gov registry record · Phase 1
Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors
A Phase 1 study of Hematopoietic Stem Cell Transplantation, sponsored by Children's Hospital Medical Center, Cincinnati.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT07375290: Recruiting Phase 1 study of Hematopoietic Stem Cell Transplantation, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT07375290 is a Phase 1 study of Hematopoietic Stem Cell Transplantation that is actively recruiting participants, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 20 participants, below the 9,789-participant average among 26 other Hematopoietic Stem Cell Transplantation trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07375290, a Phase 1 study of Hematopoietic Stem Cell Transplantation, is actively recruiting participants, sponsored by Children's Hospital Medical Center, Cincinnati.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this pilot study is to investigate the safety and preliminarily assess efficacy of early intervention with zoledronate in high risk pediatric hematopoietic stem cell transplantation (HSCT) patients to prevent the development of bone disease and fractures and reduce potential pain and suffering.
Primary Outcome
Calcium levels following infusion of zoledronate
Conditions Studied
Interventions
- DRUG Zoledronate
Study Locations (1)
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-02 |
| Est. Completion | 2028-11 |
| Phase | Phase 1 |
What NCT07375290 shows while recruiting
NCT07375290 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 9,789-participant average among 26 other Hematopoietic Stem Cell Transplantation trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Hematopoietic Stem Cell Transplantation appearing as the primary indexed condition, and to 1 intervention - of which Zoledronate is the first listed.
NCT07375290 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT07375290 about?
NCT07375290 is a clinical study titled "Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors". The purpose of this pilot study is to investigate the safety and preliminarily assess efficacy of early intervention with zoledronate in high risk pediatric hematopoietic stem cell transplantation (HSCT) patients to prevent the development of bone disease and fractures and reduce potential pain and ...
What is the current status of trial NCT07375290?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2026-02. Estimated completion is 2028-11.
What conditions does trial NCT07375290 study?
This clinical trial studies the following conditions: Hematopoietic Stem Cell Transplantation.
What interventions are being tested in trial NCT07375290?
The interventions under investigation include: Zoledronate (DRUG).
Who is sponsoring clinical trial NCT07375290?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07375290 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07375290's enrollment target sits among peer trials
20 22nd of 26 higher than 3 of 26 other Hematopoietic Stem Cell Transplantation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hematopoietic Stem Cell Transplantation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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