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2026 data Public-data reference. official source

Alopecia Areata

Open-data reference.

27 US clinical trials · 15 currently recruiting

Active & Recent Trials

RECRUITING 20,000 participants

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Sanguine Biosciences

NCT05635266

RECRUITING 5,000 participants

CorEvitas Alopecia Areata (AA) Safety and Effectiveness Registry

CorEvitas

NCT05745389

RECRUITING 1,500 participants

CorEvitas International Adolescent Alopecia Areata (AA) Drug Safety and Effectiveness Registry

CorEvitas

NCT06562270

RECRUITING Phase 3 1,500 participants

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

AbbVie

NCT06012240

RECRUITING 850 participants

Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib

Pfizer

NCT06531109

RECRUITING Phase 3 550 participants

A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata

Pfizer

NCT06873945

RECRUITING Phase 3 355 participants

Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata

Sun Pharmaceutical Industries

NCT07133308

RECRUITING Phase 2 136 participants

A Study of LAD603 in Adults With Alopecia Areata

Almirall, S.A.

NCT07311564

RECRUITING Phase 1 80 participants

A Study of DR-01 in Subjects With Alopecia Areata and Vitiligo

Dren Bio

NCT06602232

RECRUITING Phase 2 76 participants

Dupilumab in the Treatment of Pediatric Alopecia Areata

Icahn School of Medicine at Mount Sinai

NCT05866562

RECRUITING Phase 2 70 participants

Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05398809

RECRUITING Phase 2 68 participants

Regeneron AA Multicenter (Dupilumab)

Emma Guttman

NCT05551793

RECRUITING Phase 2 56 participants

Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome

Icahn School of Medicine at Mount Sinai

NCT07242638

RECRUITING Phase 2 40 participants

Evaluation of Microbiota Transplant Therapy in Patients With Alopecia Areata

University of Minnesota

NCT06747611

RECRUITING Early Phase 1 12 participants

Intralesional Cyclosporine for Alopecia Areata

University of California, Davis

NCT07029204

ACTIVE NOT RECRUITING 15,000 participants

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Target PharmaSolutions

NCT03661866

ACTIVE NOT RECRUITING 3,100 participants

Alopecia Areata Registry

M.D. Anderson Cancer Center

NCT00069589

ACTIVE NOT RECRUITING Phase 3 1,052 participants

Long-Term PF-06651600 for the Treatment of Alopecia Areata

Pfizer

NCT04006457

ACTIVE NOT RECRUITING Phase 2 1,000 participants

Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata

Sun Pharmaceutical Industries

NCT03898479

ACTIVE NOT RECRUITING Phase 2 166 participants

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Adult Participants With Severe Alopecia Areata

Sanofi

NCT06444451

ACTIVE NOT RECRUITING Phase 2 94 participants

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Severe to Very Severe Alopecia Areata in Adult Patients (Rezolve AA)

Nektar Therapeutics

NCT06340360

ACTIVE NOT RECRUITING Phase 2 75 participants

A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

Q32 Bio

NCT06018428

COMPLETED Phase 4 20 participants

Aldara for the Treatment of Extensive Alopecia Areata

Hordinsky, Maria K., MD

NCT00177021

COMPLETED Phase 2 12 participants

Pilot Study to Evaluate the Efficacy of Ruxolitinib in Alopecia Areata

Columbia University

NCT01950780

COMPLETED Phase 2 12 participants

Study To Evaluate The Efficacy Of Tofacitinib In Moderate To Severe Alopecia Areata, Totalis And Universalis

Columbia University

NCT02299297

COMPLETED 10 participants

A Study of Vitamin D in Subjects With Alopecia Areata

Avera McKennan Hospital & University Health Center

NCT01328678

COMPLETED Phase 2 1 participants

Open Label Study of ATI-50002 Topical Solution Administered to Adult Subjects With Eyebrow Loss Due to Alopecia Areata

Aclaris Therapeutics

NCT03551821

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 13
Phase 3 4
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Alopecia Areata Trial Landscape

ClinicalTrials.gov lists 27 US studies indexed under Alopecia Areata, and 15 of those are currently open to recruitment — roughly 56% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Alopecia Areata shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Alopecia Areata is led by Pfizer with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 27 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Alopecia Areata?

PlainTrial tracks 27 US clinical trials for Alopecia Areata, of which 15 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Alopecia Areata?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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