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NCT05605574 · ClinicalTrials.gov registry record · NA
Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant
A NA study of Hematopoietic Stem Cell Transplantation, sponsored by National Cancer Institute (NCI).
- Recruiting
- Registry status
- NA
- Development phase
- 222
- Enrollment target
- 2
- Study locations
NCT05605574 is a NA study of Hematopoietic Stem Cell Transplantation that is actively recruiting participants, run by National Cancer Institute (NCI). The registered enrollment target is 222 participants, below the 9,781-participant average among 26 other Hematopoietic Stem Cell Transplantation trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT05605574, a NA study of Hematopoietic Stem Cell Transplantation, is actively recruiting participants, sponsored by National Cancer Institute (NCI).
- RECRUITING
- Registry status
- NA
- Development phase
- 222 participants
- Enrollment target
- 2
- Study locations
Study Summary
Background: For adolescent and young adults (AYAs) with certain life-threatening illnesses, hematopoietic stem cell transplant (HSCT) provides the best chance for cure and survival. HSCT is a life-saving therapy, but this treatment also comes with significant risks. Given these risks, it is imperative that patients and their families have the opportunity to share their values, priorities, and goals through advance care planning (ACP) to ensure that the care they receive through the transplant process remains patient-centered. Despite the benefits of ACP discussions, many barriers, including provider discomfort, may prevent these conversations with AYAs. Objective: To see if AYAs who undergo HSCT and their caregivers benefit from discussing ACP topics. Eligibility: People aged 18 to 39 years enrolled in an NIH study with a planned HSCT. One caregiver aged 18 years or older will also be invited to participate. Design: Participants will complete a 20-minute questionnaire. They will be asked about the priorities they have related to their care and their prior experiences with ACP. Participants will have 3 conversations with a study team member over 4 to 9 weeks. Each talk will last 45 to 60 minutes. First, participants will talk about their upcoming transplant and their expectations. They will also be asked about their fears and worries and will discuss what is most important to them in terms of support, comfort, their values, and their goals. Next, they will learn about Voicing My CHOiCES . This guide gives people a place to say what kind of care they want to receive during their treatment and includes a place to document how they would want to be cared for if they can no longer make decisions on their own. Participants will be guided as they fill in a few pages from this guide. The third conversation will review the first talks. Participants may ask questions and review any topic. They will complete follow-up questionnaires and be provided with a summary of
Conditions Studied
Interventions
- BEHAVIORAL Advance Care Planning conversations
Study Locations (2)
Maryland
- Johns Hopkins University - Baltimore
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 222 participants |
| Start Date | 2022-11-16 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05605574
The ClinicalTrials.gov registry entry for NCT05605574 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 222 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 9,781-participant average among 26 other Hematopoietic Stem Cell Transplantation trials with a reported enrollment target (98% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hematopoietic Stem Cell Transplantation appearing as the primary indexed condition, and to 1 intervention - of which Advance Care Planning conversations is the first listed.
NCT05605574 reports 2 study locations spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT05605574 about?
NCT05605574 is a clinical study titled "Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant". Background: For adolescent and young adults (AYAs) with certain life-threatening illnesses, hematopoietic stem cell transplant (HSCT) provides the best chance for cure and survival. HSCT is a life-saving therapy, but this treatment also comes with significant risks. Given these risks, it is imperat...
What is the current status of trial NCT05605574?
This trial is currently recruiting. It is a NA study. The enrollment target is 222 participants. The study started on 2022-11-16. Estimated completion is 2026-12-31.
What conditions does trial NCT05605574 study?
This clinical trial studies the following conditions: Hematopoietic Stem Cell Transplantation.
What interventions are being tested in trial NCT05605574?
The interventions under investigation include: Advance Care Planning conversations (BEHAVIORAL).
Who is sponsoring clinical trial NCT05605574?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05605574 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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