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ClinicalTrials.gov 35 recruiting now official registry

Hematopoietic and Lymphoid Cell Neoplasm clinical trials

35 of 105 indexed Hematopoietic and Lymphoid Cell Neoplasm trials are currently recruiting.

105 US clinical trials · 35 currently recruiting

Hematopoietic and Lymphoid Cell Neoplasm is the subject of 105 registered US clinical trials on ClinicalTrials.gov, 35 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 44 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 44 of these trials.

The research picture

Hematopoietic and Lymphoid Cell Neoplasm has 105 registered US clinical trials, 35 of them open to new participants right now, about 33% of the total.

35
recruiting participants now
33%
of trials open to enrollment
8
in Phase 3–4 (later-stage)
44
top sponsor: M.D. Anderson Cancer Center
Phase 116Phase 228Phase 35Phase 43

Active & Recent Trials

105 total, page 2 of 3

ACTIVE NOT RECRUITING Phase 3 150 participants

Fentanyl Buccal Tablet or Morphine for Exertional Dyspnea in Cancer Patients

M.D. Anderson Cancer Center

NCT04188418

ACTIVE NOT RECRUITING NA 149 participants

Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors

City of Hope Medical Center

NCT05138991

ACTIVE NOT RECRUITING NA 133 participants

Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy

University of Rochester NCORP Research Base

NCT04888988

ACTIVE NOT RECRUITING 110 participants

Parental Attitudes and Beliefs Regarding Risks Associated With Opioid Use in Children With Cancer

M.D. Anderson Cancer Center

NCT05055011

ACTIVE NOT RECRUITING NA 107 participants

Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 Pandemic

M.D. Anderson Cancer Center

NCT05102656

ACTIVE NOT RECRUITING Phase 2 88 participants

PEA for the Relief of Chemotherapy-Induced Peripheral Neuropathy

Academic and Community Cancer Research United

NCT05246670

ACTIVE NOT RECRUITING Phase 4 84 participants

Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain

M.D. Anderson Cancer Center

NCT04296305

ACTIVE NOT RECRUITING 83 participants

Vincristine Pharmacokinetics in Infants

Children's Oncology Group

NCT05359237

ACTIVE NOT RECRUITING Phase 1 72 participants

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

M.D. Anderson Cancer Center

NCT02530034

ACTIVE NOT RECRUITING Phase 2 70 participants

Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)

National Cancer Institute (NCI)

NCT04439175

ACTIVE NOT RECRUITING Phase 2 68 participants

Cognitive Behavioral Therapy and Multimodal Therapy in Treating Sleep Disturbance in Patients With Cancer

M.D. Anderson Cancer Center

NCT01628029

ACTIVE NOT RECRUITING Phase 2 53 participants

Testing Binimetinib as a Potential Targeted Treatment in Cancers With NRAS Genetic Changes (MATCH-Subprotocol Z1A)

National Cancer Institute (NCI)

NCT04439344

ACTIVE NOT RECRUITING Phase 2 51 participants

Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease

Fred Hutchinson Cancer Center

NCT04198922

ACTIVE NOT RECRUITING Phase 2 50 participants

Testing Trametinib as a Potential Targeted Treatment in Cancers With NF1 Genetic Changes (MATCH-Subprotocol S1)

National Cancer Institute (NCI)

NCT04439318

ACTIVE NOT RECRUITING Phase 2 49 participants

Donor Cytomegalovirus-Specific Cytotoxic T-Lymphocytes in Treating Patients With a Persistent Cytomegalovirus Infection

M.D. Anderson Cancer Center

NCT02210078

ACTIVE NOT RECRUITING Phase 4 48 participants

Gardasil 9 Vaccine in Preventing HPV Infection in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

M.D. Anderson Cancer Center

NCT03023631

ACTIVE NOT RECRUITING 41 participants

Preliminary Testing of the MD Anderson Symptom Inventory (Adolescent Version)

M.D. Anderson Cancer Center

NCT02515383

ACTIVE NOT RECRUITING Phase 2 40 participants

Testing Afatinib as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol B)

National Cancer Institute (NCI)

NCT04439136

ACTIVE NOT RECRUITING NA 40 participants

A Multidisciplinary Approach to Improve the Health of Older Adults With Blood Cancers After Stem Cell Transplantation

City of Hope Medical Center

NCT04914338

ACTIVE NOT RECRUITING Phase 2 40 participants

Testing Palbociclib (PD-0332991) as a Potential Targeted Treatment in Cancers With CCND1, 2, 3 Amplification (MATCH-Subprotocol Z1B)

National Cancer Institute (NCI)

NCT04439201

ACTIVE NOT RECRUITING Phase 1 40 participants

Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer

National Cancer Institute (NCI)

NCT02862275

ACTIVE NOT RECRUITING Phase 2 38 participants

Testing Ado-Trastuzumab Emtansine as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol Q)

National Cancer Institute (NCI)

NCT04439110

ACTIVE NOT RECRUITING NA 36 participants

Telementoring Intervention (ECHO) for the Transformation of Professional Engagement, Practice Efficiency, and Community Building Through Team Meetings in Diagnostic Imaging Clinicians

M.D. Anderson Cancer Center

NCT04196972

ACTIVE NOT RECRUITING Phase 1 36 participants

CBM588 in Improving Clinical Outcomes in Patients Who Have Undergone Donor Hematopoietic Stem Cell Transplant

City of Hope Medical Center

NCT03922035

ACTIVE NOT RECRUITING Phase 2 35 participants

Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I)

National Cancer Institute (NCI)

NCT04439227

ACTIVE NOT RECRUITING Phase 2 35 participants

Testing VS-6063 (Defactinib) as a Potential Targeted Treatment in Cancers With NF2 Genetic Changes (MATCH-Subprotocol U)

National Cancer Institute (NCI)

NCT04439331

ACTIVE NOT RECRUITING Phase 2 35 participants

Testing GSK2636771 as a Potential Targeted Treatment in Cancers With PTEN Loss of Expression (MATCH-Subprotocol P)

National Cancer Institute (NCI)

NCT04439188

ACTIVE NOT RECRUITING Phase 2 35 participants

Testing Trametinib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol R)

National Cancer Institute (NCI)

NCT04439279

ACTIVE NOT RECRUITING Phase 2 35 participants

Testing AZD5363 as a Potential Targeted Treatment in Cancers With AKT Genetic Changes (MATCH-Subprotocol Y)

National Cancer Institute (NCI)

NCT04439123

ACTIVE NOT RECRUITING Phase 2 35 participants

Testing Trametinib and Dabrafenib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol H)

National Cancer Institute (NCI)

NCT04439292

ACTIVE NOT RECRUITING Phase 2 31 participants

Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

Fred Hutchinson Cancer Center

NCT03399773

ACTIVE NOT RECRUITING NA 30 participants

Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study

Ohio State University Comprehensive Cancer Center

NCT05972577

ACTIVE NOT RECRUITING Phase 1 26 participants

Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers

Jonsson Comprehensive Cancer Center

NCT04459273

ACTIVE NOT RECRUITING Phase 2 24 participants

Testing GSK2636771 as a Potential Targeted Treatment in Cancers With PTEN Genetic Changes (MATCH-Subprotocol N)

National Cancer Institute (NCI)

NCT04439149

ACTIVE NOT RECRUITING NA 20 participants

A Mobile Application, Oncpatient, to Assist Patients Undergoing Radiation Therapy

City of Hope Medical Center

NCT05173961

ACTIVE NOT RECRUITING NA 20 participants

The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer

City of Hope Medical Center

NCT05023993

ACTIVE NOT RECRUITING Phase 2 19 participants

Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E)

National Cancer Institute (NCI)

NCT06303167

ACTIVE NOT RECRUITING Phase 1 11 participants

Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

National Cancer Institute (NCI)

NCT02993146

ACTIVE NOT RECRUITING Phase 4 10 participants

Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome

M.D. Anderson Cancer Center

NCT04745910

ACTIVE NOT RECRUITING Phase 2 7 participants

Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

City of Hope Medical Center

NCT04060277

ACTIVE NOT RECRUITING Phase 2 5 participants

Testing Crizotinib as a Potential Targeted Treatment in Cancers With ALK Genetic Changes (MATCH-Subprotocol F)

National Cancer Institute (NCI)

NCT04439266

ACTIVE NOT RECRUITING Phase 2 4 participants

Testing Crizotinib as a Potential Targeted Treatment in Cancers With ROS1 Genetic Changes (MATCH-Subprotocol G)

National Cancer Institute (NCI)

NCT04439253

ACTIVE NOT RECRUITING Phase 2 4 participants

Testing Trametinib as a Potential Targeted Treatment in Cancers With GNAQ or GNA11 Genetic Changes (MATCH-Subprotocol S2)

National Cancer Institute (NCI)

NCT04439357

ACTIVE NOT RECRUITING 1 participants

Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes

M.D. Anderson Cancer Center

NCT04743466

COMPLETED NA 50,207 participants

Enhanced, EHR-facilitated Cancer Symptom Control Pragmatic Clinical Trial

Mayo Clinic

NCT03892967

COMPLETED 232 participants

Impact of Aminoglycosides in Hypotensive Septic Oncology Patients

M.D. Anderson Cancer Center

NCT05045963

COMPLETED 229 participants

Perioperative Care in the Cancer Patient -1, ARCA-1 Study

M.D. Anderson Cancer Center

NCT04491409

COMPLETED 223 participants

Distress Associated with Coronavirus Disease 2019 and Telehealth on Supportive Care Patients with Advanced Cancer

M.D. Anderson Cancer Center

NCT05058339

COMPLETED NA 76 participants

Geriatric Assessment Screening Tool for the Identification of At-Risk Older Adults Who Are Undergoing Cancer Treatment

Thomas Jefferson University

NCT04788758

COMPLETED Phase 1 41 participants

Azacitidine and Oxaliplatin In Treating Patients With Advanced Cancers Relapsed or Refractory to Any Platinum Therapy

National Cancer Institute (NCI)

NCT01039155

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Phase Distribution

PhaseTrial count
Phase 1 16
Phase 2 28
Phase 3 5
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hematopoietic and Lymphoid Cell Neoplasm Trial Landscape

105 indexed Hematopoietic and Lymphoid Cell Neoplasm studies · 35 recruiting (33%).

Phase mix: 8 late (III/IV) vs 44 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (44 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hematopoietic and Lymphoid Cell Neoplasm?

PlainTrial tracks 105 US clinical trials for Hematopoietic and Lymphoid Cell Neoplasm, of which 35 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hematopoietic and Lymphoid Cell Neoplasm?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.