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NCT05138991 · ClinicalTrials.gov registry record · NA
Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors
A NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, sponsored by City of Hope Medical Center.
- Active
- Registry status
- NA
- Development phase
- 149
- Enrollment target
- 1
- Study location
NCT05138991: Active NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, sponsored by City of Hope Medical Center.
NCT05138991 is a NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm that is active but no longer recruiting, run by City of Hope Medical Center. The registered enrollment target is 149 participants, below the 1,140-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05138991, a NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, is active but no longer recruiting, sponsored by City of Hope Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 149 participants
- Enrollment target
- 1
- Study location
Study Summary
The clinical trial compares the reproducibility and accuracy of cardiac tonometry-based portable systems that may detect early cardiac dysfunction (SphygmoCor® Xcel and Oscar 2™ ambulatory blood pressure monitor) at home and in the clinic to currently available screening tests for heart failure including echocardiogram (echo) and cardiovascular magnetic resonance (CMR). The SphygmoCor® Xcel and Oscar 2™ systems may help detect cardiac dysfunction earlier than other available screening tests because it can be self-administered outside of the clinic. This study aims to test the accuracy and practicality of these devices in the clinic setting and at home.
Primary Outcome
Validate the accuracy of ejection fraction, as measured using a tonometry-based system (SphygmoCor® Xcel), in the clinic setting, and determine the reproducibility (Oscar 2™) at home.
Conditions Studied
Interventions
- OTHER Questionnaire Administration
- PROCEDURE Echocardiogram Recording
- PROCEDURE Stress Cardiac Magnetic Resonance Imaging
- DEVICE Wireless Synchronized Cardiac Function Monitoring Device
Study Locations (1)
California
- City of Hope Medical Center - Duarte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 149 participants |
| Start Date | 2022-06-22 |
| Est. Completion | 2026-07-16 |
| Phase | NA |
What the registry record for NCT05138991 still lists
NCT05138991 is an interventional study that assigns participants to a tested intervention. The registered 149 participants enrollment target is mid-sized for trials with a published cap, below the 1,140-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 4 interventions - of which Questionnaire Administration is the first listed.
NCT05138991 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05138991 about?
NCT05138991 is a clinical study titled "Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors". The clinical trial compares the reproducibility and accuracy of cardiac tonometry-based portable systems that may detect early cardiac dysfunction (SphygmoCor® Xcel and Oscar 2™ ambulatory blood pressure monitor) at home and in the clinic to currently available screening tests for heart failure incl...
What is the current status of trial NCT05138991?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 149 participants. The study started on 2022-06-22. Estimated completion is 2026-07-16.
What conditions does trial NCT05138991 study?
This clinical trial studies the following conditions: Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm.
What interventions are being tested in trial NCT05138991?
The interventions under investigation include: Questionnaire Administration (OTHER), Echocardiogram Recording (PROCEDURE), Stress Cardiac Magnetic Resonance Imaging (PROCEDURE), Wireless Synchronized Cardiac Function Monitoring Device (DEVICE).
Who is sponsoring clinical trial NCT05138991?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05138991 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Malignant Solid Neoplasm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05138991's enrollment target sits among peer trials
149 78th of 176 higher than 99 of 176 other Malignant Solid Neoplasm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Malignant Solid Neoplasm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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