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NCT04888988 · ClinicalTrials.gov registry record · NA
Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy
A NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, sponsored by University of Rochester NCORP Research Base.
- Active
- Registry status
- NA
- Development phase
- 133
- Enrollment target
- 20
- Study locations
NCT04888988: Active NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, sponsored by University of Rochester NCORP Research Base.
NCT04888988 is a NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm that is active but no longer recruiting, run by University of Rochester NCORP Research Base. The registered enrollment target is 133 participants, below the 1,140-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (88% lower). The trial reports 20 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04888988, a NA study of Malignant Solid Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm, is active but no longer recruiting, sponsored by University of Rochester NCORP Research Base.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 133 participants
- Enrollment target
- 20
- Study locations
Study Summary
This phase II trial studies whether using exercise is better than the usual approach for treating chemotherapy-induced peripheral neuropathy (CIPN). CIPN occurs when chemotherapy damages the nerves communicating between the brain, spinal cord, and the rest of the body. The usual approach for treating CIPN is treatment with drugs that help reduce symptoms of other types of neuropathy (for example, from diabetes). However, these drugs do not treat all symptoms of CIPN. Exercise may help to reduce CIPN symptoms.
Primary Outcome
Will estimate the effects of exercise versus usual care on CIPN using analysis of covariance (ANCOVA). Will be measured by the mean European Organization for Research and Treatment of Cancer-CIPN20. The model will include CIPN-20 at Week 6 as the outcome, treatment group (exercise vs. usual care) as the independent variable of interest and the pre-intervention CIPN-20 score as a covariate.
Conditions Studied
Interventions
- PROCEDURE Magnetic Resonance Imaging
- OTHER Exercise Intervention
- OTHER Best Practice
- OTHER Exercise Counseling
- OTHER Neuropathy Assessment
Study Locations (20)
California
- Kaiser Permanente-Fresno - Fresno
- Contra Costa Regional Medical Center - Martinez
- Kaiser Permanente-Roseville - Roseville
- Kaiser Permanente Downtown Commons - Sacramento
- Kaiser Permanente-South Sacramento - Sacramento
- Kaiser Permanente-Santa Teresa-San Jose - San Jose
- Kaiser Permanente San Leandro - San Leandro
- Kaiser San Rafael-Gallinas - San Rafael
- Kaiser Permanente Medical Center - Santa Clara - Santa Clara
- Kaiser Permanente-South San Francisco - South San Francisco
- Kaiser Permanente-Vallejo - Vallejo
- Kaiser Permanente-Walnut Creek - Walnut Creek
Colorado
- Rocky Mountain Cancer Centers-Aurora - Aurora
- Boulder Community Foothills Hospital - Boulder
- Rocky Mountain Cancer Centers-Boulder - Boulder
- Rocky Mountain Cancer Centers - Centennial - Centennial
- The Women's Imaging Center - Denver
- Colorado Blood Cancer Institute - Denver
- Rocky Mountain Cancer Centers-Midtown - Denver
- Rocky Mountain Cancer Centers-Rose - Denver
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 133 participants |
| Start Date | 2022-02-25 |
| Est. Completion | 2026-02-01 |
| Phase | NA |
What the registry record for NCT04888988 still lists
NCT04888988 is an interventional study that assigns participants to a tested intervention. The registered 133 participants enrollment target is mid-sized for trials with a published cap, below the 1,140-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (88% lower).
The record links to 3 conditions, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 5 interventions - of which Magnetic Resonance Imaging is the first listed.
NCT04888988 names 20 study sites across 2 states, led by California, Colorado.
Frequently Asked Questions
What is clinical trial NCT04888988 about?
NCT04888988 is a clinical study titled "Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy". This phase II trial studies whether using exercise is better than the usual approach for treating chemotherapy-induced peripheral neuropathy (CIPN). CIPN occurs when chemotherapy damages the nerves communicating between the brain, spinal cord, and the rest of the body. The usual approach for treatin...
What is the current status of trial NCT04888988?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 133 participants. The study started on 2022-02-25. Estimated completion is 2026-02-01.
What conditions does trial NCT04888988 study?
This clinical trial studies the following conditions: Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm, Chemotherapy-induced Peripheral Neuropathy.
What interventions are being tested in trial NCT04888988?
The interventions under investigation include: Magnetic Resonance Imaging (PROCEDURE), Exercise Intervention (OTHER), Best Practice (OTHER), Exercise Counseling (OTHER), Neuropathy Assessment (OTHER).
Who is sponsoring clinical trial NCT04888988?
This trial is sponsored by University of Rochester NCORP Research Base, which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04888988 being conducted?
This trial has 20 study locations across California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Malignant Solid Neoplasm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04888988's enrollment target sits among peer trials
133 82nd of 176 higher than 95 of 176 other Malignant Solid Neoplasm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Malignant Solid Neoplasm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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