Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy
NCT04888988 · View on ClinicalTrials.gov ↗
Study Summary
This phase II trial studies whether using exercise is better than the usual approach for treating chemotherapy-induced peripheral neuropathy (CIPN). CIPN occurs when chemotherapy damages the nerves communicating between the brain, spinal cord, and the rest of the body. The usual approach for treating CIPN is treatment with drugs that help reduce symptoms of other types of neuropathy (for example, from diabetes). However, these drugs do not treat all symptoms of CIPN. Exercise may help to reduce CIPN symptoms.
Conditions Studied
Interventions
- PROCEDURE Magnetic Resonance Imaging
- OTHER Exercise Intervention
- OTHER Best Practice
- OTHER Exercise Counseling
- OTHER Neuropathy Assessment
Study Locations (20)
California
- Kaiser Permanente-Fresno — Fresno
- Contra Costa Regional Medical Center — Martinez
- Kaiser Permanente-Roseville — Roseville
- Kaiser Permanente Downtown Commons — Sacramento
- Kaiser Permanente-South Sacramento — Sacramento
- Kaiser Permanente-Santa Teresa-San Jose — San Jose
- Kaiser Permanente San Leandro — San Leandro
- Kaiser San Rafael-Gallinas — San Rafael
- Kaiser Permanente Medical Center - Santa Clara — Santa Clara
- Kaiser Permanente-South San Francisco — South San Francisco
- Kaiser Permanente-Vallejo — Vallejo
- Kaiser Permanente-Walnut Creek — Walnut Creek
Colorado
- Rocky Mountain Cancer Centers-Aurora — Aurora
- Boulder Community Foothills Hospital — Boulder
- Rocky Mountain Cancer Centers-Boulder — Boulder
- Rocky Mountain Cancer Centers - Centennial — Centennial
- The Women's Imaging Center — Denver
- Colorado Blood Cancer Institute — Denver
- Rocky Mountain Cancer Centers-Midtown — Denver
- Rocky Mountain Cancer Centers-Rose — Denver
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 133 participants |
| Start Date | 2022-02-25 |
| Est. Completion | 2026-02-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04888988
The ClinicalTrials.gov registry entry for NCT04888988 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 133 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Rochester NCORP Research Base, which has 8 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 5 interventions — of which Magnetic Resonance Imaging is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04888988 reports 20 study locations spanning 2 distinct geographic areas — top geographies include California, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04888988 about?
NCT04888988 is a clinical study titled "Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy". This phase II trial studies whether using exercise is better than the usual approach for treating chemotherapy-induced peripheral neuropathy (CIPN). CIPN occurs when chemotherapy damages the nerves communicating between the brain, spinal cord, and the rest of the body. The usual approach for treatin...
What is the current status of trial NCT04888988?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 133 participants. The study started on 2022-02-25. Estimated completion is 2026-02-01.
What conditions does trial NCT04888988 study?
This clinical trial studies the following conditions: Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm, Chemotherapy-Induced Peripheral Neuropathy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04888988?
The interventions under investigation include: Magnetic Resonance Imaging (PROCEDURE), Exercise Intervention (OTHER), Best Practice (OTHER), Exercise Counseling (OTHER), Neuropathy Assessment (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04888988?
This trial is sponsored by University of Rochester NCORP Research Base, which has 8 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04888988 being conducted?
This trial has 20 study locations across California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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